3O8A | pdb_00003o8a

Crystal structure of Plasmodium falciparum dihydroorotate dehydrogenase bound with novel Inhibitor Genz667348

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Sequence of
     ​M​​G​​S​​S​​H​​H​​H​​H​​H​​H​     ​S​​S​​G​​L​​V​​P​​R​​G​​S​​H​     ​M​​A​​S​​M​​T​​G​​G​​Q​​Q​​G​     ​R​​D​​P​​F​​E​​S​​Y​​N​​P​​E​165  ​F​​F​​L​​Y​​D​​I​​F​​L​​K​​F​175  ​C​​L​​K​​Y​​I​​D​​G​​E​​I​​C​185  ​H​​D​​L​​F​​L​​L​​L​​G​​K​​Y​195  ​N​​I​​L​​P​​Y​​D​​T​​S​​N​​D​205  ​S​​I​​Y​​A​​C​​T​​N​​I​​K​​H​215  ​L​​D​​F​​I​​N​​P​​F​​G​​V​​A​225  ​A​​G​​F​​D​​K​​N​​G​​V​​C​​I​235  ​D​​S​​I​​L​​K​​L​​G​​F​​S​​F​245  ​I​​E​​I​​G​​T​​I​​T​​P​​R​​G​255  ​Q​​T​​G​​N​​A​​K​​P​​R​​I​​F​265  ​R​​D​​V​​E​​S​​R​​S​​I​​I​​N​275  ​S​​C​​G​​F​​N​​N​​M​​G​​C​​D​285  ​K​​V​​T​​E​​N​​L​​I​​L​​F​​R​295  ​K​​R​​Q​​E​​E​​D​​K​​L​​L​​S​305  ​K​​H​​I​​V​​G​​V​​S​​I​​G​​K​315  ​N​​K​​D​​T​​V​​N​​I​​V​​D​​D​325  ​L​​K​​Y​​C​​I​​N​​K​​I​​G​​R​335  ​Y​​A​​D​​Y​​I​​A​​I​​N​​V​​S​345  ​S​​P​​N​​T​​P​​G​​L​​R​​D​​N​355  ​Q​​E​​A​​G​​K​​L​​K​​N​​I​​I​365  ​L​​S​​V​​K​​E​​E​​I​​D​​N​​L​375  ​E​​K​​N​​N​​I​​M​​N​​D​​E​​F​415  ​L​​W​​F​​N​​T​​T​​K​​K​​K​​P​425  ​L​​V​​F​​V​​K​​L​​A​​P​​D​​L​435  ​N​​Q​​E​​Q​​K​​K​​E​​I​​A​​D​445  ​V​​L​​L​​E​​T​​N​​I​​D​​G​​M​455  ​I​​I​​S​​N​​T​​T​​T​​Q​​I​​N​465  ​D​​I​​K​​S​​F​​E​​N​​K​​K​​G​475  ​G​​V​​S​​G​​A​​K​​L​​K​​D​​I​485  ​S​​T​​K​​F​​I​​C​​E​​M​​Y​​N​495  ​Y​​T​​N​​K​​Q​​I​​P​​I​​I​​A​505  ​S​​G​​G​​I​​F​​S​​G​​L​​D​​A​515  ​L​​E​​K​​I​​E​​A​​G​​A​​S​​V​525  ​C​​Q​​L​​Y​​S​​C​​L​​V​​F​​N​535  ​G​​M​​K​​S​​A​​V​​Q​​I​​K​​R​545  ​E​​L​​N​​H​​L​​L​​Y​​Q​​R​​G​555  ​Y​​Y​​N​​L​​K​​E​​A​​I​​G​​R​565  ​K​​H​​S​​K​​S​
Type
Asm Id
Dynamic Bonds

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