3PDJ | pdb_00003pdj

Crystal Structure of Human 11-beta-Hydroxysteroid Dehydrogenase 1 (11b-HSD1) in Complex with 4,4-Disubstituted Cyclohexylbenzamide Inhibitor

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20   ​Q​​Q​​P​​L​​N​​E​​E​​F​​R​​P​30   ​E​​M​​L​​Q​​G​​K​​K​​V​​I​​V​40   ​T​​G​​A​​S​​K​​G​​I​​G​​R​​E​50   ​M​​A​​Y​​H​​L​​A​​K​​M​​G​​A​60   ​H​​V​​V​​V​​T​​A​​R​​S​​K​​E​70   ​T​​L​​Q​​K​​V​​V​​S​​H​​C​​L​80   ​E​​L​​G​​A​​A​​S​​A​​H​​Y​​I​90   ​A​​G​​T​​M​​E​​D​​M​​T​​F​​A​100  ​E​​Q​​F​​V​​A​​Q​​A​​G​​K​​L​110  ​M​​G​​G​​L​​D​​M​​L​​I​​L​​N​120  ​H​​I​​T​​N​​T​​S​​L​​N​​L​​F​130  ​H​​D​​D​​I​​H​​H​​V​​R​​K​​S​140  ​M​​E​​V​​N​​F​​L​​S​​Y​​V​​V​150  ​L​​T​​V​​A​​A​​L​​P​​M​​L​​K​160  ​Q​​S​​N​​G​​S​​I​​V​​V​​V​​S​170  ​S​​L​​A​​G​​K​​V​​A​​Y​​P​​M​180  ​V​​A​​A​​Y​​S​​A​​S​​K​​F​​A​190  ​L​​D​​G​​F​​F​​S​​S​​I​​R​​K​200  ​E​​Y​​S​​V​​S​​R​​V​​N​​V​​S​210  ​I​​T​​L​​C​​V​​L​​G​​L​​I​​D​220  ​T​​E​​T​​A​​M​​K​​A​​V​​S​​G​230  ​I​​V​​H​​M​​Q​​A​​A​​P​​K​​E​240  ​E​​C​​A​​L​​E​​I​​I​​K​​G​​G​250  ​A​​L​​R​​Q​​E​​E​​V​​Y​​Y​​D​260  ​S​​S​​L​​W​​T​​T​​L​​L​​I​​R​270  ​N​​P​​S​​R​​K​​I​​L​​E​​F​​L​280  ​Y​​S​​T​​S​​Y​​N​​M​​D​​R​​F​290  ​I​​N​​K​
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