4W2R | pdb_00004w2r

Structure of Hs/AcPRC2 in complex with 5,8-dichloro-2-[(4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-7-[(R)-methoxy(oxetan-3-yl)methyl]-3,4-dihydroisoquinolin-1(2H)-one

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RCSB PDB Mol* Viewer 2.11.2 [1/27/2025, 4:56:27 PM]
Sequence of
     ​M​​G​​Q​​T​​G​​K​​K​​S​​E​​K​11   ​G​​P​​I​​C​​W​​R​​K​​R​​V​​K​21   ​S​​E​​Y​​M​​R​​L​​R​​Q​​L​​K​31   ​R​​F​​R​​R​​A​​D​​E​​V​​K​​S​41   ​M​​F​​N​​S​​N​​R​​Q​​K​​I​​Q​51   ​E​​R​​T​​E​​I​​L​​N​​Q​​E​​W​61   ​K​​Q​​R​​R​​I​​Q​​P​​V​​H​​I​71   ​M​​T​​S​​V​​S​​S​​L​​R​​G​​T​81   ​R​​E​​C​​S​​V​​T​​S​​D​​L​​D​91   ​F​​P​​K​​Q​​V​​I​​P​​L​​K​​T​101  ​L​​N​​A​​V​​A​​S​​V​​P​​I​​M​111  ​Y​​S​​W​​S​​P​​L​​Q​​Q​​N​​F​121  ​M​​V​​E​​D​​E​​T​​V​​L​​H​​N​     ​I​​P​​Y​​M​​G​​D​​E​​V​​L​​D​     ​Q​​D​​G​​T​​F​​I​​E​​E​​L​​I​     ​K​​N​​Y​​D​​G​​K​​V​​H​​G​​D​     ​R​​E​​C​​G​​F​​I​​N​​D​​E​​I​171  ​F​​V​​E​​L​​V​​N​​A​​L​​G​​Q​181  ​L​​D​​R​​R​​D​​E​​K​​Q​​K​​N​     ​Q​​E​​S​​N​​Q​​I​​D​​K​​E​​S​     ​H​​P​​P​​R​​K​​F​​P​​S​​D​​K​211  ​I​​F​​E​​A​​I​​S​​S​​M​​F​​P​221  ​D​​K​​G​​T​​A​​E​​E​​L​​K​​E​231  ​K​​Y​​K​​E​​L​​T​​E​​Q​​Q​​L​     ​P​​G​​A​​L​​P​​P​​E​​C​​T​​P​251  ​N​​I​​D​​G​​P​​N​​A​​K​​S​​V​261  ​Q​​R​​E​​Q​​S​​L​​H​​S​​F​​H​271  ​T​​L​​F​​C​​R​​R​​C​​F​​K​​Y​281  ​D​​C​​F​​L​​H​​P​​F​​H​​A​​T​291  ​P​​N​​T​​Y​​K​​R​​K​​N​​T​​E​     ​M​​A​​I​​D​​N​​K​​P​​C​​G​​P​     ​H​​C​​Y​​Q​​H​​L​​E​​G​​A​​K​     ​E​​F​​A​​A​​A​​L​​T​​A​​E​​N​     ​V​​E​​W​​S​​G​​A​​E​​A​​S​​M​341  ​F​​R​​V​​L​​I​​G​​T​​Y​​Y​​D​351  ​N​​F​​C​​A​​I​​A​​R​​L​​I​​G​361  ​T​​K​​T​​C​​R​​Q​​V​​Y​​E​​F​371  ​R​​V​​K​​E​​S​​S​​I​​I​​A​​P​     ​A​​P​​A​​E​​D​​V​​D​​T​​L​​G​     ​G​​G​​G​​S​​G​​G​​G​​G​​S​​G​     ​G​​G​​G​​S​​A​​A​​A​​D​​G​​S​     ​S​​N​​H​​V​​Y​​N​​Y​​Q​​P​​C​421  ​D​​H​​P​​R​​Q​​P​​C​​D​​N​​S​431  ​C​​P​​C​​V​​I​​A​​Q​​N​​F​​C​441  ​E​​K​​F​​C​​Q​​C​​S​​S​​E​​C​451  ​Q​​N​​R​​F​​P​​G​​C​​R​​C​​K​461  ​A​​Q​​C​​N​​T​​K​​Q​​C​​P​​C​471  ​Y​​L​​A​​V​​R​​E​​C​​D​​P​​D​481  ​L​​C​​L​​T​​C​​G​​A​​A​​D​​H​491  ​W​​D​​S​​K​​N​​V​​S​​C​​K​​N​501  ​C​​S​​I​​Q​​R​​G​​S​​K​​K​​H​511  ​L​​L​​L​​A​​P​​S​​D​​V​​A​​G​521  ​W​​G​​I​​F​​I​​K​​D​​P​​V​​Q​531  ​K​​N​​E​​F​​I​​S​​E​​Y​​C​​G​541  ​E​​I​​I​​S​​Q​​D​​E​​A​​D​​R​551  ​R​​G​​K​​V​​Y​​D​​K​​Y​​M​​C​561  ​S​​F​​L​​F​​N​​L​​N​​N​​D​​F​571  ​V​​V​​D​​A​​T​​R​​K​​G​​N​​K​581  ​I​​R​​F​​A​​N​​H​​S​​V​​N​​P​591  ​N​​C​​Y​​A​​K​​V​​M​​M​​V​​N​601  ​G​​D​​H​​R​​I​​G​​I​​F​​A​​K​611  ​R​​A​​I​​Q​​T​​G​​E​​E​​L​​F​621  ​F​​D​​Y​​R​​Y​​S​​Q​​A​​D​​A​     ​L​​K​​Y​​V​​G​​I​​E​​R​​E​​M​     ​E​​I​​P​
Type
Asm Id
Dynamic Bonds

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