Structural mechanisms of extracellular ion exchange and induced binding-site occlusion in the sodium-calcium exchanger NCX_Mj soaked with 100 mM Na+ and 10mM Sr2+

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RCSB PDB Mol* Viewer 2.10.6 [10/28/2024, 3:56:31 PM]
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1    ​M​​V​​I​​L​​G​​V​​G​​Y​​F​​L​11   ​L​​G​​L​​I​​L​​L​​Y​​Y​​G​​S​21   ​D​​W​​F​​V​​L​​G​​S​​E​​R​​I​31   ​A​​R​​H​​F​​N​​V​​S​​N​​F​​V​41   ​I​​G​​A​​T​​V​​M​​A​​I​​G​​T​51   ​S​​L​​P​​E​​I​​L​​T​​S​​A​​Y​61   ​A​​S​​Y​​M​​H​​A​​P​​G​​I​​S​71   ​I​​G​​N​​A​​I​​G​​S​​C​​I​​C​81   ​N​​I​​G​​L​​V​​L​​G​​L​​S​​A​91   ​I​​I​​S​​P​​I​​I​​V​​D​​K​​N​101  ​L​​Q​​K​​N​​I​​L​​V​​Y​​L​​L​111  ​F​​V​​I​​F​​A​​A​​V​​I​​G​​I​121  ​D​​G​​F​​S​​W​​I​​D​​G​​V​​V​131  ​L​​L​​I​​L​​F​​I​​I​​Y​​L​​R​141  ​W​​T​​V​​K​​N​​G​​S​​A​​E​​I​151  ​E​​E​​N​​N​​D​​K​​N​​N​​P​​S​161  ​V​​V​​F​​S​​L​​V​​L​​L​​I​​I​171  ​G​​L​​I​​G​​V​​L​​V​​G​​A​​E​181  ​L​​F​​V​​D​​G​​A​​K​​K​​I​​A​191  ​L​​A​​L​​D​​I​​S​​D​​K​​V​​I​201  ​G​​F​​T​​L​​V​​A​​F​​G​​T​​S​211  ​L​​P​​E​​L​​M​​V​​S​​L​​A​​A​221  ​A​​K​​R​​N​​L​​G​​G​​M​​V​​L​231  ​G​​N​​V​​I​​G​​S​​N​​I​​A​​D​241  ​I​​G​​G​​A​​L​​A​​V​​G​​S​​L​251  ​F​​M​​H​​L​​P​​A​​E​​N​​V​​Q​261  ​M​​A​​V​​L​​V​​I​​M​​S​​L​​L​271  ​L​​Y​​L​​F​​A​​K​​Y​​S​​K​​I​281  ​G​​R​​W​​Q​​G​​I​​L​​F​​L​​A​291  ​L​​Y​​I​​I​​A​​I​​A​​S​​L​​R​301  ​M​​G​
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