Crystal structures of AKR1C3 ternary complex with NADP+ and the chromene derivative 2l

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Sequence of
     ​G​​S​​M​​D​​S​​K​​H​​Q​​C​​V​9    ​K​​L​​N​​D​​G​​H​​F​​M​​P​​V​19   ​L​​G​​F​​G​​T​​Y​​A​​P​​P​​E​29   ​V​​P​​R​​S​​K​​A​​L​​E​​V​​T​39   ​K​​L​​A​​I​​E​​A​​G​​F​​R​​H​49   ​I​​D​​S​​A​​H​​L​​Y​​N​​N​​E​59   ​E​​Q​​V​​G​​L​​A​​I​​R​​S​​K​69   ​I​​A​​D​​G​​S​​V​​K​​R​​E​​D​79   ​I​​F​​Y​​T​​S​​K​​L​​W​​S​​T​89   ​F​​H​​R​​P​​E​​L​​V​​R​​P​​A​99   ​L​​E​​N​​S​​L​​K​​K​​A​​Q​​L​109  ​D​​Y​​V​​D​​L​​Y​​L​​I​​H​​S​119  ​P​​M​​S​​L​​K​​P​​G​​E​​E​​L​129  ​S​​P​​T​​D​​E​​N​​G​​K​​V​​I​139  ​F​​D​​I​​V​​D​​L​​C​​T​​T​​W​149  ​E​​A​​M​​E​​K​​C​​K​​D​​A​​G​159  ​L​​A​​K​​S​​I​​G​​V​​S​​N​​F​169  ​N​​R​​R​​Q​​L​​E​​M​​I​​L​​N​179  ​K​​P​​G​​L​​K​​Y​​K​​P​​V​​C​189  ​N​​Q​​V​​E​​C​​H​​P​​Y​​F​​N​199  ​R​​S​​K​​L​​L​​D​​F​​C​​K​​S​209  ​K​​D​​I​​V​​L​​V​​A​​Y​​S​​A​219  ​L​​G​​S​​Q​​R​​D​​K​​R​​W​​V​229  ​D​​P​​N​​S​​P​​V​​L​​L​​E​​D​239  ​P​​V​​L​​C​​A​​L​​A​​K​​K​​H​249  ​K​​R​​T​​P​​A​​L​​I​​A​​L​​R​259  ​Y​​Q​​L​​Q​​R​​G​​V​​V​​V​​L​269  ​A​​K​​S​​Y​​N​​E​​Q​​R​​I​​R​279  ​Q​​N​​V​​Q​​V​​F​​E​​F​​Q​​L​289  ​T​​A​​E​​D​​M​​K​​A​​I​​D​​G​299  ​L​​D​​R​​N​​L​​H​​Y​​F​​N​​S​309  ​D​​S​​F​​A​​S​​H​​P​​N​​Y​​P​319  ​Y​​S​​D​​E​​Y​
Type
Asm Id
Dynamic Bonds

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