7PR7 | pdb_00007pr7

Crystal structure of human heparanase in complex with covalent inhibitor VL166

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Sequence of
159  ​K​​F​​K​​N​​S​​T​​Y​​S​​R​​S​169  ​S​​V​​D​​V​​L​​Y​​T​​F​​A​​N​179  ​C​​S​​G​​L​​D​​L​​I​​F​​G​​L​189  ​N​​A​​L​​L​​R​​T​​A​​D​​L​​Q​199  ​W​​N​​S​​S​​N​​A​​Q​​L​​L​​L​209  ​D​​Y​​C​​S​​S​​K​​G​​Y​​N​​I​219  ​S​​W​​E​​L​​G​​N​​E​​P​​N​​S​229  ​F​​L​​K​​K​​A​​D​​I​​F​​I​​N​239  ​G​​S​​Q​​L​​G​​E​​D​​F​​I​​Q​249  ​L​​H​​K​​L​​L​​R​​K​​S​​T​​F​259  ​K​​N​​A​​K​​L​​Y​​G​​P​​D​​V​269  ​G​​Q​​P​​R​​R​​K​​T​​A​​K​​M​279  ​L​​K​​S​​F​​L​​K​​A​​G​​G​​E​289  ​V​​I​​D​​S​​V​​T​​W​​H​​H​​Y​299  ​Y​​L​​N​​G​​R​​T​​A​​T​​R​​E​309  ​D​​F​​L​​N​​P​​D​​V​​L​​D​​I​319  ​F​​I​​S​​S​​V​​Q​​K​​V​​F​​Q​329  ​V​​V​​E​​S​​T​​R​​P​​G​​K​​K​339  ​V​​W​​L​​G​​E​​T​​S​​S​​A​​Y​349  ​G​​G​​G​​A​​P​​L​​L​​S​​D​​T​359  ​F​​A​​A​​G​​F​​M​​W​​L​​D​​K​369  ​L​​G​​L​​S​​A​​R​​M​​G​​I​​E​379  ​V​​V​​M​​R​​Q​​V​​F​​F​​G​​A​389  ​G​​N​​Y​​H​​L​​V​​D​​E​​N​​F​399  ​D​​P​​L​​P​​D​​Y​​W​​L​​S​​L​409  ​L​​F​​K​​K​​L​​V​​G​​T​​K​​V​419  ​L​​M​​A​​S​​V​​Q​​G​​S​​K​​R​429  ​R​​K​​L​​R​​V​​Y​​L​​H​​C​​T​439  ​N​​T​​D​​N​​P​​R​​Y​​K​​E​​G​449  ​D​​L​​T​​L​​Y​​A​​I​​N​​L​​H​459  ​N​​V​​T​​K​​Y​​L​​R​​L​​P​​Y​469  ​P​​F​​S​​N​​K​​Q​​V​​D​​K​​Y​479  ​L​​L​​R​​P​​L​​G​​P​​H​​G​​L​489  ​L​​S​​K​​S​​V​​Q​​L​​N​​G​​L​499  ​T​​L​​K​​M​​V​​D​​D​​Q​​T​​L​509  ​P​​P​​L​​M​​E​​K​​P​​L​​R​​P​519  ​G​​S​​S​​L​​G​​L​​P​​A​​F​​S​529  ​Y​​S​​F​​F​​V​​I​​R​​N​​A​​K​539  ​V​​A​​A​​C​​I​
Type
Asm Id
Dynamic Bonds

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