Human inositol 1,4,5-trisphosphate 3-kinase A (IP3K) catalytic domain in complex with D-3-deoxy-myo-inositol 1,4,6-trisphosphate/ATP/Mn

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RCSB PDB Mol* Viewer 2.11.1 [12/17/2024, 1:59:56 PM]
Sequence of
183  ​G​​S​​H​​M​​S​​W​​V​​Q​​L​​A​     ​G​​H​​T​​G​​S​​F​​K​​A​​A​​G​203  ​T​​S​​G​​L​​I​​L​​K​​R​​C​​S​213  ​E​​P​​E​​R​​Y​​C​​L​​A​​R​​L​223  ​M​​A​​D​​A​​L​​R​​G​​C​​V​​P​233  ​A​​F​​H​​G​​V​​V​​E​​R​​D​​G​243  ​E​​S​​Y​​L​​Q​​L​​Q​​D​​L​​L​253  ​D​​G​​F​​D​​G​​P​​C​​V​​L​​D​263  ​C​​K​​M​​G​​V​​R​​T​​Y​​L​​E​273  ​E​​E​​L​​T​​K​​A​​R​​E​​R​​P​283  ​K​​L​​R​​K​​D​​M​​Y​​K​​K​​M​293  ​L​​A​​V​​D​​P​​E​​A​​P​​T​​E​303  ​E​​E​​H​​A​​Q​​R​​A​​V​​T​​K​313  ​P​​R​​Y​​M​​Q​​W​​R​​E​​G​​I​323  ​S​​S​​S​​T​​T​​L​​G​​F​​R​​I​333  ​E​​G​​I​​K​​K​​A​​D​​G​​S​​C​343  ​S​​T​​D​​F​​K​​T​​T​​R​​S​​R​353  ​E​​Q​​V​​L​​R​​V​​F​​E​​E​​F​363  ​V​​Q​​G​​D​​E​​E​​V​​L​​R​​R​373  ​Y​​L​​N​​R​​L​​Q​​Q​​I​​R​​D​383  ​T​​L​​E​​V​​S​​E​​F​​F​​R​​R​393  ​H​​E​​V​​I​​G​​S​​S​​L​​L​​F​403  ​V​​H​​D​​H​​C​​H​​R​​A​​G​​V​413  ​W​​L​​I​​D​​F​​G​​K​​T​​T​​P​423  ​L​​P​​D​​G​​Q​​I​​L​​D​​H​​R​433  ​R​​P​​W​​E​​E​​G​​N​​R​​E​​D​443  ​G​​Y​​L​​L​​G​​L​​D​​N​​L​​I​453  ​G​​I​​L​​A​​S​​L​​A​​E​​R​
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Dynamic Bonds

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