8U37 | pdb_00008u37

Crystal structure of the catalytic domain of human PKC alpha (D463N, V568I, S657E) in complex with NVP-CJL037 at 2.48-A resolution

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     ​G​​P​​S​​E​​D​​R​​K​​Q​​P​​S​     ​N​​N​​L​​D​​R​​V​​K​​L​​T​​D​339  ​F​​N​​F​​L​​M​​V​​L​​G​​K​​G​349  ​S​​F​​G​​K​​V​​M​​L​​A​​D​​R​359  ​K​​G​​T​​E​​E​​L​​Y​​A​​I​​K​369  ​I​​L​​K​​K​​D​​V​​V​​I​​Q​​D​379  ​D​​D​​V​​E​​C​​T​​M​​V​​E​​K​389  ​R​​V​​L​​A​​L​​L​​D​​K​​P​​P​399  ​F​​L​​T​​Q​​L​​H​​S​​C​​F​​Q​409  ​T​​V​​D​​R​​L​​Y​​F​​V​​M​​E​419  ​Y​​V​​N​​G​​G​​D​​L​​M​​Y​​H​429  ​I​​Q​​Q​​V​​G​​K​​F​​K​​E​​P​439  ​Q​​A​​V​​F​​Y​​A​​A​​E​​I​​S​449  ​I​​G​​L​​F​​F​​L​​H​​K​​R​​G​459  ​I​​I​​Y​​R​​N​​L​​K​​L​​D​​N​469  ​V​​M​​L​​D​​S​​E​​G​​H​​I​​K​479  ​I​​A​​D​​F​​G​​M​​C​​K​​E​​H​489  ​M​​M​​D​​G​​V​​T​​T​​R​​TPO​​F​499  ​C​​G​​T​​P​​D​​Y​​I​​A​​P​​E​509  ​I​​I​​A​​Y​​Q​​P​​Y​​G​​K​​S​519  ​V​​D​​W​​W​​A​​Y​​G​​V​​L​​L​529  ​Y​​E​​M​​L​​A​​G​​Q​​P​​P​​F​539  ​D​​G​​E​​D​​E​​D​​E​​L​​F​​Q​549  ​S​​I​​M​​E​​H​​N​​V​​S​​Y​​P​559  ​K​​S​​L​​S​​K​​E​​A​​V​​S​​I​569  ​C​​K​​G​​L​​M​​T​​K​​H​​P​​A​579  ​K​​R​​L​​G​​C​​G​​P​​E​​G​​E​589  ​R​​D​​V​​R​​E​​H​​A​​F​​F​​R​599  ​R​​I​​D​​W​​E​​K​​L​​E​​N​​R​609  ​E​​I​​Q​​P​​P​​F​​K​​P​​K​​V​     ​C​​G​​K​​G​​A​​E​​N​​F​​D​​K​     ​F​​F​​T​​R​​G​​Q​​P​​V​​L​​TPO​639  ​P​​P​​D​​Q​​L​​V​​I​​A​​N​​I​649  ​D​​Q​​S​​D​​F​​E​​G​​F​​E​​Y​659  ​V​​N​​P​​Q​​F​​V​​H​​P​​I​​L​     ​Q​​S​​A​​V​
Type
Asm Id
Dynamic Bonds

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