Cryo-EM structure of SARS-CoV-2 S trimer in the early fusion intermediate conformation (E-FIC) (focused refinement of intact S2)
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RCSB PDB Mol* Viewer 2.11.3-dev-js-update.1 [4/3/2025, 1:43:51 AM]
Sequence of
MFVFLVLLPL VSSQCVNLTT RTQLPPAYTN SFTRGVYYPD KVFRSSVLHS TQDLFLPFFS NVTWFHAIHV SGTNGTKRFD NPVLPFNDGV YFASTEKSNI IRGWIFGTTL DSKTQSLLIV NNATNVVIKV CEFQFCNDPF LGVYYHKNNK SWMESEFRVY SSANNCTFEY VSQPFLMDLE GKQGNFKNLR EFVFKNIDGY FKIYSKHTPI NLVRDLPQGF SALEPLVDLP IGINITRFQT LLALHRSYLT PGDSSSGWTA GAAAYYVGYL QPRTFLLKYN ENGTITDAVD CALDPLSETK CTLKSFTVEK GIYQTSNFRV QPTESIVRFP NITNLCPFGE VFNATRFASV YAWNRKRISN CVADYSVLYN SASFSTFKCY GVSPTKLNDL CFTNVYADSF VIRGDEVRQI APGQTGKIAD YNYKLPDDFT GCVIAWNSNN LDSKVGGNYN YLYRLFRKSN LKPFERDIST EIYQAGSTPC NGVEGFNCYF PLQSYGFQPT NGVGYQPYRV VVLSFELLHA PATVCGPKKS TNLVKNKCVN FNFNGLTGTG VLTESNKKFL PFQQFGRDIA DTTDAVRDPQ TLEILDITPC SFGGVSVITP GTNTSNQVAV LYQGVNCTEV PVAIHADQLT PTWRVYSTGS NVFQTRAGCL IGAEHVNNSY ECDIPIGAGI CASYQTQTNS PRRARSVASQ SIIAYTMSLG AENSVAYSNN711 SIAIPTNFTI721 SVTTEILPVS731 MTKTSVDCTM741 YICGDSTECS751 NLLLQYGSFC761 TQLNRALTGI771 AVEQDKNTQE781 VFAQVKQIYK791 TPPIKDFGGF801 NFSQILPDPS811 KPSKRSFIED821 LLFNKVTLAD831 AGFIKQYGDC841 LGDIAARDLI851 CAQKFNGLTV861 LPPLLTDEMI871 AQYTSALLAG881 TITSGWTFGA891 GAALQIPFAM901 QMAYRFNGIG911 VTQNVLYENQ921 KLIANQFNSA931 IGKIQDSLSS941 TASALGKLQD951 VVNQNAQALN961 TLVKQLSSNF971 GAISSVLNDI981 LSRLDKVEAE991 VQIDRLITGR1001 LQSLQTYVTQ1011 QLIRAAEIRA1021 SANLAATKMS1031 ECVLGQSKRV1041 DFCGKGYHLM1051 SFPQSAPHGV1061 VFLHVTYVPA1071 QEKNFTTAPA1081 ICHDGKAHFP1091 REGVFVSNGT1101 HWFVTQRNFY1111 EPQIITTDNT1121 FVSGNCDVVI1131 GIVNNTVYDP1141 LQPELDSFKE ELDKYFKNHT SPDVDLGDIS GINASVVNIQ KEIDRLNEVA KNLNESLIDL QELGKYEQGS GYIPEAPRDG QAYVRKDGEW VFLSTFLSGL EVLFQGPGGW SHPQFEKGGG SGGGSGGSAW SHPQFEKGGS HHHHHHHH
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