1TD9

Crystal Structure of a Phosphotransacetylase from Bacillus subtilis

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
B	d1td9b1	Alpha and beta proteins (a/b)	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Phosphotransacetylase	Phosphotransacetylase Pta	(Bacillus subtilis ) [TaxId: 1423 ],	SCOPe (2.08)
B	d1td9b2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Bacillus subtilis ) [TaxId: 1423 ],	SCOPe (2.08)
C	d1td9c_	Alpha and beta proteins (a/b)	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Phosphotransacetylase	Phosphotransacetylase Pta	(Bacillus subtilis ) [TaxId: 1423 ],	SCOPe (2.08)
E	d1td9e_	Alpha and beta proteins (a/b)	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Phosphotransacetylase	Phosphotransacetylase Pta	(Bacillus subtilis ) [TaxId: 1423 ],	SCOPe (2.08)
A	d1td9a_	Alpha and beta proteins (a/b)	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Phosphotransacetylase	Phosphotransacetylase Pta	(Bacillus subtilis ) [TaxId: 1423 ],	SCOPe (2.08)
D	d1td9d1	Alpha and beta proteins (a/b)	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Phosphotransacetylase	Phosphotransacetylase Pta	(Bacillus subtilis ) [TaxId: 1423 ],	SCOPe (2.08)
D	d1td9d2	Artifacts	Tags	Tags	Tags	N-terminal Tags	(Bacillus subtilis ) [TaxId: 1423 ],	SCOPe (2.08)
F	d1td9f_	Alpha and beta proteins (a/b)	Isocitrate/Isopropylmalate dehydrogenase-like	Isocitrate/Isopropylmalate dehydrogenase-like	Phosphotransacetylase	Phosphotransacetylase Pta	(Bacillus subtilis ) [TaxId: 1423 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
B	SCOP2B Superfamily	Isocitrate/Isopropylmalate dehydrogenase-like	8043815	3001375	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Isocitrate/Isopropylmalate dehydrogenase-like	8043815	3001375	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Isocitrate/Isopropylmalate dehydrogenase-like	8043815	3001375	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Isocitrate/Isopropylmalate dehydrogenase-like	8043815	3001375	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Isocitrate/Isopropylmalate dehydrogenase-like	8043815	3001375	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Isocitrate/Isopropylmalate dehydrogenase-like	8043815	3001375	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	PTA_PTB	e1td9B2	A: a/b three-layered sandwiches	X: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	H: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	T: Isocitrate/Isopropylmalate dehydrogenase-like	F: PTA_PTB	ECOD (1.6)
C	PTA_PTB	e1td9C1	A: a/b three-layered sandwiches	X: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	H: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	T: Isocitrate/Isopropylmalate dehydrogenase-like	F: PTA_PTB	ECOD (1.6)
E	PTA_PTB	e1td9E2	A: a/b three-layered sandwiches	X: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	H: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	T: Isocitrate/Isopropylmalate dehydrogenase-like	F: PTA_PTB	ECOD (1.6)
A	PTA_PTB	e1td9A1	A: a/b three-layered sandwiches	X: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	H: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	T: Isocitrate/Isopropylmalate dehydrogenase-like	F: PTA_PTB	ECOD (1.6)
D	PTA_PTB	e1td9D1	A: a/b three-layered sandwiches	X: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	H: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	T: Isocitrate/Isopropylmalate dehydrogenase-like	F: PTA_PTB	ECOD (1.6)
F	PTA_PTB	e1td9F1	A: a/b three-layered sandwiches	X: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	H: Isocitrate/Isopropylmalate dehydrogenase-like (From Topology)	T: Isocitrate/Isopropylmalate dehydrogenase-like	F: PTA_PTB	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	3.40.50.10950	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold		CATH (4.3.0)
B	3.40.50.10750	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Isocitrate/Isopropylmalate dehydrogenase-like	CATH (4.3.0)
C	3.40.50.10950	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold		CATH (4.3.0)
C	3.40.50.10750	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Isocitrate/Isopropylmalate dehydrogenase-like	CATH (4.3.0)
E	3.40.50.10950	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold		CATH (4.3.0)
E	3.40.50.10750	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Isocitrate/Isopropylmalate dehydrogenase-like	CATH (4.3.0)
A	3.40.50.10950	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold		CATH (4.3.0)
A	3.40.50.10750	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Isocitrate/Isopropylmalate dehydrogenase-like	CATH (4.3.0)
D	3.40.50.10950	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold		CATH (4.3.0)
D	3.40.50.10750	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Isocitrate/Isopropylmalate dehydrogenase-like	CATH (4.3.0)
F	3.40.50.10950	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold		CATH (4.3.0)
F	3.40.50.10750	Alpha Beta	3-Layer(aba) Sandwich	Rossmann fold	Isocitrate/Isopropylmalate dehydrogenase-like	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F	PF01515	Phosphate acetyl/butaryl transferase (PTA_PTB)	Phosphate acetyl/butaryl transferase	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F	Phosphate acetyltransferase	acetyltransferase activity acyltransferase activity acyltransferase activity, transferring groups other than amino-acyl groups transferase activity phosphate acetyltransferase activity catalytic activity	thioester biosynthetic process acetyl-CoA metabolic process nucleobase-containing compound metabolic process acyl-CoA metabolic process nucleobase-containing small molecule metabolic process purine-containing compound biosynthetic process acyl-CoA biosynthetic process phosphate-containing compound metabolic process sulfur compound metabolic process small molecule metabolic process amide metabolic process thioester metabolic process phosphorus metabolic process nucleoside phosphate metabolic process thioester biosynthetic process acetyl-CoA metabolic process nucleobase-containing compound metabolic process acyl-CoA metabolic process nucleobase-containing small molecule metabolic process purine-containing compound biosynthetic process acyl-CoA biosynthetic process phosphate-containing compound metabolic process sulfur compound metabolic process small molecule metabolic process amide metabolic process thioester metabolic process phosphorus metabolic process nucleoside phosphate metabolic process primary metabolic process amide biosynthetic process nucleobase-containing compound biosynthetic process purine-containing compound metabolic process acetyl-CoA biosynthetic process sulfur compound biosynthetic process biosynthetic process organophosphate metabolic process organophosphate biosynthetic process nucleoside phosphate biosynthetic process metabolic process cellular process	cellular anatomical structure intracellular anatomical structure cytoplasm

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F	IPR050500	Phosphate Acetyltransferase/Butyryltransferase	Family
A, B, C, D, E A, B, C, D, E, F	IPR012147	Phosphate acetyl/butyryltransferase	Family
A, B, C, D, E A, B, C, D, E, F	IPR042112	Phosphate acetyltransferase, domain 2	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F	IPR004614	Phosphate acetyltransferase	Domain
A, B, C, D, E A, B, C, D, E, F	IPR002505	Phosphate acetyl/butaryl transferase	Domain
A, B, C, D, E A, B, C, D, E, F	IPR042113	Phosphate acetyltransferase, domain 1	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.