1APX
CRYSTAL STRUCTURE OF RECOMBINANT ASCORBATE PEROXIDASE
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | d1apxb_ | All alpha proteins | Heme-dependent peroxidases | Heme-dependent peroxidases | CCP-like | Ascorbate peroxidase | pea (Pisum sativum ) [TaxId: 3888 ], | SCOPe (2.08) |
C | d1apxc_ | All alpha proteins | Heme-dependent peroxidases | Heme-dependent peroxidases | CCP-like | Ascorbate peroxidase | pea (Pisum sativum ) [TaxId: 3888 ], | SCOPe (2.08) |
D | d1apxd_ | All alpha proteins | Heme-dependent peroxidases | Heme-dependent peroxidases | CCP-like | Ascorbate peroxidase | pea (Pisum sativum ) [TaxId: 3888 ], | SCOPe (2.08) |
A | d1apxa_ | All alpha proteins | Heme-dependent peroxidases | Heme-dependent peroxidases | CCP-like | Ascorbate peroxidase | pea (Pisum sativum ) [TaxId: 3888 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
B | SCOP2B Superfamily | Heme-dependent peroxidases | 8038257 | 3000844 | SCOP2B (2022-06-29) |
C | SCOP2B Superfamily | Heme-dependent peroxidases | 8038257 | 3000844 | SCOP2B (2022-06-29) |
D | SCOP2B Superfamily | Heme-dependent peroxidases | 8038257 | 3000844 | SCOP2B (2022-06-29) |
A | SCOP2 Family | CCP-like | 8025878 | 4001128 | SCOP2 (2022-06-29) |
A | SCOP2 Superfamily | Heme-dependent peroxidases | 8038257 | 3000844 | SCOP2 (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | peroxidase | e1apxB1 | A: alpha complex topology | X: Heme-dependent peroxidases (From Topology) | H: Heme-dependent peroxidases (From Topology) | T: Heme-dependent peroxidases | F: peroxidase | ECOD (1.6) |
C | peroxidase | e1apxC1 | A: alpha complex topology | X: Heme-dependent peroxidases (From Topology) | H: Heme-dependent peroxidases (From Topology) | T: Heme-dependent peroxidases | F: peroxidase | ECOD (1.6) |
D | peroxidase | e1apxD1 | A: alpha complex topology | X: Heme-dependent peroxidases (From Topology) | H: Heme-dependent peroxidases (From Topology) | T: Heme-dependent peroxidases | F: peroxidase | ECOD (1.6) |
A | peroxidase | e1apxA1 | A: alpha complex topology | X: Heme-dependent peroxidases (From Topology) | H: Heme-dependent peroxidases (From Topology) | T: Heme-dependent peroxidases | F: peroxidase | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
B | 1.10.520.10 | Mainly Alpha | Orthogonal Bundle | Peroxidase | domain 1 | CATH (4.3.0) |
B | 1.10.420.10 | Mainly Alpha | Orthogonal Bundle | Peroxidase | domain 2 | CATH (4.3.0) |
C | 1.10.520.10 | Mainly Alpha | Orthogonal Bundle | Peroxidase | domain 1 | CATH (4.3.0) |
C | 1.10.420.10 | Mainly Alpha | Orthogonal Bundle | Peroxidase | domain 2 | CATH (4.3.0) |
D | 1.10.520.10 | Mainly Alpha | Orthogonal Bundle | Peroxidase | domain 1 | CATH (4.3.0) |
D | 1.10.420.10 | Mainly Alpha | Orthogonal Bundle | Peroxidase | domain 2 | CATH (4.3.0) |
A | 1.10.520.10 | Mainly Alpha | Orthogonal Bundle | Peroxidase | domain 1 | CATH (4.3.0) |
A | 1.10.420.10 | Mainly Alpha | Orthogonal Bundle | Peroxidase | domain 2 | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR002016 | Haem peroxidase | Domain | |
IPR019794 | Peroxidase, active site | Active Site | |
IPR010255 | Haem peroxidase superfamily | Homologous Superfamily | |
IPR002207 | Class I peroxidase | Family | |
IPR044831 | Heme-binding peroxidase Ccp1-like | Family | |
IPR019793 | Peroxidases heam-ligand binding site | Binding Site |
Structure Motif Annotation: Mechanism and Catalytic Site Atlas M-CSA Database Homepage
Chains | Enzyme Name | Description | Catalytic Residues |
---|---|---|---|
L-ascorbate peroxidase M-CSA #399 | L-ascorbate peroxidase (AP) is a heme peroxidase. This group of enzyme catalyse the reduction of hydrogen peroxide (H2O2) to water and the concurrent oxidisation of a range of substrates, in this case ascorbic acid. | Defined by 5 residues: ARG:A-37 [auth A-38]HIS:A-41 [auth A-42]HIS:A-162 [auth A-163]TRP:A-178 [auth A-179]ASP:A-207 [auth A-208] | EC: 1.11.1.11 (PDB Primary Data) |