1BMF
BOVINE MITOCHONDRIAL F1-ATPASE
External Resource: Annotation
- Domain Annotation: SCOP/SCOPe Classification
- Domain Annotation: SCOP2 Classification
- Domain Annotation: ECOD Classification
- Domain Annotation: CATH
- Protein Family Annotation
- Gene Ontology: Gene Product Annotation
- InterPro: Protein Family Classification
- Membrane Protein Annotation: mpstruc
- Structure Motif: Primary M-CSA Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
D | SCOP2B Superfamily | RecA-like P-loop NTPases | 8018253 | 3002019 | SCOP2B (2022-06-29) |
D | SCOP2B Superfamily | ATP synthase alpha/beta C-terminal domain-like | 8056904 | 3000684 | SCOP2B (2022-06-29) |
D | SCOP2B Superfamily | ATP synthase alpha/beta N-terminal domain-like | 8018258 | 3001034 | SCOP2B (2022-06-29) |
E | SCOP2B Superfamily | ATP synthase alpha/beta N-terminal domain-like | 8018258 | 3001034 | SCOP2B (2022-06-29) |
E | SCOP2B Superfamily | RecA-like P-loop NTPases | 8018253 | 3002019 | SCOP2B (2022-06-29) |
E | SCOP2B Superfamily | ATP synthase alpha/beta C-terminal domain-like | 8056904 | 3000684 | SCOP2B (2022-06-29) |
F | SCOP2B Superfamily | ATP synthase alpha/beta N-terminal domain-like | 8018258 | 3001034 | SCOP2B (2022-06-29) |
F | SCOP2B Superfamily | ATP synthase alpha/beta C-terminal domain-like | 8056904 | 3000684 | SCOP2B (2022-06-29) |
F | SCOP2B Superfamily | RecA-like P-loop NTPases | 8018253 | 3002019 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | RecA-like P-loop NTPases | 8018243 | 3002019 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | ATP synthase alpha/beta C-terminal domain-like | 8056868 | 3000684 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | ATP synthase alpha/beta N-terminal domain-like | 8018248 | 3001034 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | ATP synthase alpha/beta N-terminal domain-like | 8018248 | 3001034 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | RecA-like P-loop NTPases | 8018243 | 3002019 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | ATP synthase alpha/beta C-terminal domain-like | 8056868 | 3000684 | SCOP2B (2022-06-29) |
C | SCOP2B Superfamily | ATP synthase alpha/beta N-terminal domain-like | 8018248 | 3001034 | SCOP2B (2022-06-29) |
C | SCOP2B Superfamily | RecA-like P-loop NTPases | 8018243 | 3002019 | SCOP2B (2022-06-29) |
C | SCOP2B Superfamily | ATP synthase alpha/beta C-terminal domain-like | 8056868 | 3000684 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
D | ATP-synt_ab_N | e1bmfD1 | A: beta barrels | X: cradle loop barrel | H: RIFT-related | T: Alanine racemase-C | F: ATP-synt_ab_N | ECOD (1.6) |
D | ATP-synt_ab_C | e1bmfD3 | A: alpha superhelices | X: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology) | H: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology) | T: C-terminal domain of alpha and beta subunits of F1 ATP synthase | F: ATP-synt_ab_C | ECOD (1.6) |
D | ATP-synt_ab | e1bmfD2 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: ATP-synt_ab | ECOD (1.6) |
E | ATP-synt_ab_N | e1bmfE1 | A: beta barrels | X: cradle loop barrel | H: RIFT-related | T: Alanine racemase-C | F: ATP-synt_ab_N | ECOD (1.6) |
E | ATP-synt_ab_C | e1bmfE3 | A: alpha superhelices | X: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology) | H: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology) | T: C-terminal domain of alpha and beta subunits of F1 ATP synthase | F: ATP-synt_ab_C | ECOD (1.6) |
E | ATP-synt_ab | e1bmfE2 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: ATP-synt_ab | ECOD (1.6) |
F | ATP-synt_ab_N | e1bmfF1 | A: beta barrels | X: cradle loop barrel | H: RIFT-related | T: Alanine racemase-C | F: ATP-synt_ab_N | ECOD (1.6) |
F | ATP-synt_ab_C | e1bmfF3 | A: alpha superhelices | X: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology) | H: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology) | T: C-terminal domain of alpha and beta subunits of F1 ATP synthase | F: ATP-synt_ab_C | ECOD (1.6) |
F | ATP-synt_ab | e1bmfF2 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: ATP-synt_ab | ECOD (1.6) |
A | ATP-synt_ab_N | e1bmfA1 | A: beta barrels | X: cradle loop barrel | H: RIFT-related | T: Alanine racemase-C | F: ATP-synt_ab_N | ECOD (1.6) |
A | ATP-synt_ab_C | e1bmfA2 | A: alpha superhelices | X: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology) | H: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology) | T: C-terminal domain of alpha and beta subunits of F1 ATP synthase | F: ATP-synt_ab_C | ECOD (1.6) |
A | ATP-synt_ab | e1bmfA3 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: ATP-synt_ab | ECOD (1.6) |
B | ATP-synt_ab_N | e1bmfB1 | A: beta barrels | X: cradle loop barrel | H: RIFT-related | T: Alanine racemase-C | F: ATP-synt_ab_N | ECOD (1.6) |
B | ATP-synt_ab_C | e1bmfB2 | A: alpha superhelices | X: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology) | H: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology) | T: C-terminal domain of alpha and beta subunits of F1 ATP synthase | F: ATP-synt_ab_C | ECOD (1.6) |
B | ATP-synt_ab | e1bmfB3 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: ATP-synt_ab | ECOD (1.6) |
C | ATP-synt_ab_N | e1bmfC1 | A: beta barrels | X: cradle loop barrel | H: RIFT-related | T: Alanine racemase-C | F: ATP-synt_ab_N | ECOD (1.6) |
C | ATP-synt_ab_C | e1bmfC2 | A: alpha superhelices | X: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology) | H: C-terminal domain of alpha and beta subunits of F1 ATP synthase (From Topology) | T: C-terminal domain of alpha and beta subunits of F1 ATP synthase | F: ATP-synt_ab_C | ECOD (1.6) |
C | ATP-synt_ab | e1bmfC3 | A: a/b three-layered sandwiches | X: P-loop domains-like | H: P-loop domains-related | T: P-loop containing nucleoside triphosphate hydrolases | F: ATP-synt_ab | ECOD (1.6) |
G | ATP-synt | e1bmfG1 | A: a/b three-layered sandwiches | X: ATP synthase (F1-ATPase), gamma subunit (From Topology) | H: ATP synthase (F1-ATPase), gamma subunit (From Topology) | T: ATP synthase (F1-ATPase), gamma subunit | F: ATP-synt | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00006 | ATP synthase alpha/beta family, nucleotide-binding domain (ATP-synt_ab) | ATP synthase alpha/beta family, nucleotide-binding domain | This entry includes the ATP synthase alpha and beta subunits, the ATP synthase associated with flagella and the termination factor Rho. | Domain | |
PF22919 | C-terminal domain of V and A type ATP synthase (ATP-synt_VA_C) | C-terminal domain of V and A type ATP synthase | This entry represents a small alpha helical domain found at the C-terminus of a variety of ATP synthases. | Domain | |
PF02874 | ATP synthase alpha/beta family, beta-barrel domain (ATP-synt_ab_N) | ATP synthase alpha/beta family, beta-barrel domain | This family includes the ATP synthase alpha and beta subunits the ATP synthase associated with flagella. | Domain | |
PF00006 | ATP synthase alpha/beta family, nucleotide-binding domain (ATP-synt_ab) | ATP synthase alpha/beta family, nucleotide-binding domain | This entry includes the ATP synthase alpha and beta subunits, the ATP synthase associated with flagella and the termination factor Rho. | Domain | |
PF00306 | ATP synthase alpha/beta chain, C terminal domain (ATP-synt_ab_C) | ATP synthase alpha/beta chain, C terminal domain | - | Domain | |
PF02874 | ATP synthase alpha/beta family, beta-barrel domain (ATP-synt_ab_N) | ATP synthase alpha/beta family, beta-barrel domain | This family includes the ATP synthase alpha and beta subunits the ATP synthase associated with flagella. | Domain | |
PF00231 | ATP synthase (ATP-synt) | ATP synthase | - | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Membrane Protein Annotation: mpstruc mpstruc Database Homepage
Chains | Resource Link | Group | Subgroup | Protein |
---|---|---|---|---|
mpstruc | TRANSMEMBRANE PROTEINS: ALPHA-HELICAL | F-type ATPase | ATP synthase (F1c10) |
Structure Motif Annotation: Mechanism and Catalytic Site Atlas M-CSA Database Homepage
Chains | Enzyme Name | Description | Catalytic Residues |
---|---|---|---|
H+-transporting two-sector ATPase (F-type, mitochondrial) M-CSA #178 | Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1, containing the extramembraneous catalytic core, and F0, containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. Subunits alpha and beta form the catalytic core in F1. F-type-ATPase utilises the proton motive force generated by photosynthesis and oxidative phosphorylation to synthesise ATP. It also catalyses the hydrolysis of ATP. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Rotation of the central stalk against the surrounding alpha3beta3 subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. | Defined by 4 residues: ARG:C-373LYS:D-166 [auth D-162]GLU:D-192 [auth D-188]ARG:D-193 [auth D-189] | EC: 7.1.2.2 (UniProt) |