1Q2J | pdb_00001q2j

Structural basis for tetrodotoxin-resistant sodium channel binding by mu-conotoxin SmIIIA

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Protein Modification Annotation

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1q2ja_	Peptides	Conotoxins	Conotoxins	mu-conotoxin	Mu-conotoxin smIIIa	Fly-specked cone (Conus stercusmuscarum ) [TaxId: 89452 ],	SCOPe (2.08)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Mu-conotoxin SmIIIA	monoatomic cation transmembrane transporter activity channel regulator activity monoatomic ion channel activity sodium channel activity molecular function inhibitor activity passive transmembrane transporter activity transporter inhibitor activity inorganic molecular entity transmembrane transporter activity molecular function regulator activity inorganic cation transmembrane transporter activity sodium channel regulator activity transporter activity channel inhibitor activity ion channel regulator activity monoatomic cation transmembrane transporter activity channel regulator activity monoatomic ion channel activity sodium channel activity molecular function inhibitor activity passive transmembrane transporter activity transporter inhibitor activity inorganic molecular entity transmembrane transporter activity molecular function regulator activity inorganic cation transmembrane transporter activity sodium channel regulator activity transporter activity channel inhibitor activity ion channel regulator activity ion channel inhibitor activity sodium ion transmembrane transporter activity monoatomic cation channel activity sodium channel inhibitor activity channel activity monoatomic ion transmembrane transporter activity transporter regulator activity metal ion transmembrane transporter activity transmembrane transporter activity toxin activity	-	cellular anatomical structure extracellular region

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR008036	Conotoxin, mu-type	Family

Protein Modification Annotation

Modified Residue(s)
Chain	Residue(s)	Description
A	PCA	Parent Component: GLN RESID: AA0031 PSI-MOD : 2-pyrrolidone-5-carboxylic acid (Gln) MOD:00040 , 2-pyrrolidone-5-carboxylic acid (Glu) MOD:00420

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.