Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
Bpdi_dom_likee2yajB2 A: few secondary structure elementsX: HIPIP (high potential iron protein) (From Topology)H: HIPIP (high potential iron protein) (From Topology)T: HIPIP (high potential iron protein)F: pdi_dom_likeECOD (1.6)
BEUF08672e2yajB1 A: few secondary structure elementsX: HIPIP (high potential iron protein) (From Topology)H: HIPIP (high potential iron protein) (From Topology)T: HIPIP (high potential iron protein)F: EUF08672ECOD (1.6)
Dpdi_dom_likee2yajD2 A: few secondary structure elementsX: HIPIP (high potential iron protein) (From Topology)H: HIPIP (high potential iron protein) (From Topology)T: HIPIP (high potential iron protein)F: pdi_dom_likeECOD (1.6)
DEUF08672e2yajD1 A: few secondary structure elementsX: HIPIP (high potential iron protein) (From Topology)H: HIPIP (high potential iron protein) (From Topology)T: HIPIP (high potential iron protein)F: EUF08672ECOD (1.6)
APFL-likee2yajA1 A: a/b barrelsX: Ten stranded beta/alpha barrel (From Topology)H: Ten stranded beta/alpha barrel (From Topology)T: Ten stranded beta/alpha barrelF: PFL-likeECOD (1.6)
APFL-likee2yajA2 A: extended segmentsX: Glycyl radical domain (From Topology)H: Glycyl radical domain (From Topology)T: Glycyl radical domainF: PFL-likeECOD (1.6)
CPFL-likee2yajC1 A: a/b barrelsX: Ten stranded beta/alpha barrel (From Topology)H: Ten stranded beta/alpha barrel (From Topology)T: Ten stranded beta/alpha barrelF: PFL-likeECOD (1.6)
CPFL-likee2yajC2 A: extended segmentsX: Glycyl radical domain (From Topology)H: Glycyl radical domain (From Topology)T: Glycyl radical domainF: PFL-likeECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
B, D
PF186714-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal (4HPAD_g_N)4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal4-Hydroxyphenylacetate decarboxylase (4-HPAD) is a heterotetramer consisting of catalytic beta-subunit harboring the putative glycyl/thiyl dyad and a distinct small gamma-subunit with two [4Fe-4S] clusters (EC:4.1.1.83). The gamma-subunit is proposed ...4-Hydroxyphenylacetate decarboxylase (4-HPAD) is a heterotetramer consisting of catalytic beta-subunit harboring the putative glycyl/thiyl dyad and a distinct small gamma-subunit with two [4Fe-4S] clusters (EC:4.1.1.83). The gamma-subunit is proposed to be involved in the regulation of the oligomeric state and catalytic activity of the enzyme and it comprises two domains with some amino acid sequence identity that are structurally related by a pseudo-2-fold symmetry indicating a gene duplication origin. This entry represents the N-terminal domain which binds one [4Fe-4S] cluster through His3, Cys6, Cys19, and Cys36 [1].
Domain
B, D
PF18524High potential iron-sulfur protein like (HPIP_like)High potential iron-sulfur protein likeThis is a C-terminal domain found in 4-hydroxyphenylacetate decarboxylase small subunit (EC:4.1.1.83), which catalyzes the last reaction in the fermentative production of p-cresol from tyrosine. The C-terminal domain [4F-4S] cluster bears structural ...This is a C-terminal domain found in 4-hydroxyphenylacetate decarboxylase small subunit (EC:4.1.1.83), which catalyzes the last reaction in the fermentative production of p-cresol from tyrosine. The C-terminal domain [4F-4S] cluster bears structural similarity to high-potential iron-sulfur proteins (HiPIPs). HiPIPs have an N-terminal extension of 20-40 residues, so the structural similarity is limited to their Fe/S cluster-binding scaffold. Furthermore, despite of the weak amino acid sequence identity, the cluster binding motifs are remarkably similar to H/CX2CX12-13CX16-17C for the gamma-subunit and CX2CX13-19CX14-19C for HiPIPs [1].
Domain
A, C
PF01228Glycine radical (Gly_radical)Glycine radical- Domain