2YAJ
CRYSTAL STRUCTURE OF GLYCYL RADICAL ENZYME with bound substrate
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | pdi_dom_like | e2yajB2 | A: few secondary structure elements | X: HIPIP (high potential iron protein) (From Topology) | H: HIPIP (high potential iron protein) (From Topology) | T: HIPIP (high potential iron protein) | F: pdi_dom_like | ECOD (1.6) |
B | EUF08672 | e2yajB1 | A: few secondary structure elements | X: HIPIP (high potential iron protein) (From Topology) | H: HIPIP (high potential iron protein) (From Topology) | T: HIPIP (high potential iron protein) | F: EUF08672 | ECOD (1.6) |
D | pdi_dom_like | e2yajD2 | A: few secondary structure elements | X: HIPIP (high potential iron protein) (From Topology) | H: HIPIP (high potential iron protein) (From Topology) | T: HIPIP (high potential iron protein) | F: pdi_dom_like | ECOD (1.6) |
D | EUF08672 | e2yajD1 | A: few secondary structure elements | X: HIPIP (high potential iron protein) (From Topology) | H: HIPIP (high potential iron protein) (From Topology) | T: HIPIP (high potential iron protein) | F: EUF08672 | ECOD (1.6) |
A | PFL-like | e2yajA1 | A: a/b barrels | X: Ten stranded beta/alpha barrel (From Topology) | H: Ten stranded beta/alpha barrel (From Topology) | T: Ten stranded beta/alpha barrel | F: PFL-like | ECOD (1.6) |
A | PFL-like | e2yajA2 | A: extended segments | X: Glycyl radical domain (From Topology) | H: Glycyl radical domain (From Topology) | T: Glycyl radical domain | F: PFL-like | ECOD (1.6) |
C | PFL-like | e2yajC1 | A: a/b barrels | X: Ten stranded beta/alpha barrel (From Topology) | H: Ten stranded beta/alpha barrel (From Topology) | T: Ten stranded beta/alpha barrel | F: PFL-like | ECOD (1.6) |
C | PFL-like | e2yajC2 | A: extended segments | X: Glycyl radical domain (From Topology) | H: Glycyl radical domain (From Topology) | T: Glycyl radical domain | F: PFL-like | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
B | 2.20.70.100 | Mainly Beta | Single Sheet | Ubiquitin Ligase Nedd4 | Chain: W | CATH (4.3.0) |
D | 2.20.70.100 | Mainly Beta | Single Sheet | Ubiquitin Ligase Nedd4 | Chain: W | CATH (4.3.0) |
A | 3.20.70.20 | Alpha Beta | Alpha-Beta Barrel | Anaerobic Ribonucleotide-triphosphate Reductase Large Chain | CATH (4.3.0) | |
C | 3.20.70.20 | Alpha Beta | Alpha-Beta Barrel | Anaerobic Ribonucleotide-triphosphate Reductase Large Chain | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF18671 | 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal (4HPAD_g_N) | 4-Hydroxyphenylacetate decarboxylase subunit gamma N-terminal | 4-Hydroxyphenylacetate decarboxylase (4-HPAD) is a heterotetramer consisting of catalytic beta-subunit harboring the putative glycyl/thiyl dyad and a distinct small gamma-subunit with two [4Fe-4S] clusters (EC:4.1.1.83). The gamma-subunit is proposed ... | Domain | |
PF18524 | High potential iron-sulfur protein like (HPIP_like) | High potential iron-sulfur protein like | This is a C-terminal domain found in 4-hydroxyphenylacetate decarboxylase small subunit (EC:4.1.1.83), which catalyzes the last reaction in the fermentative production of p-cresol from tyrosine. The C-terminal domain [4F-4S] cluster bears structural ... | Domain | |
PF01228 | Glycine radical (Gly_radical) | Glycine radical | - | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
Chains | Polymer | Molecular Function | Biological Process | Cellular Component |
---|---|---|---|---|
4-HYDROXYPHENYLACETATE DECARBOXYLASE SMALL SUBUNIT | - | - | ||
4-HYDROXYPHENYLACETATE DECARBOXYLASE LARGE SUBUNIT | - |
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR041125 | 4-hydroxyphenylacetate decarboxylase small gamma subunit, N-terminal | Domain | |
IPR053727 | HPA decarboxylase small subunit superfamily | Homologous Superfamily | |
IPR040923 | 4-hydroxyphenylacetate decarboxylase small gamma subunit, C-terminal | Domain | |
IPR051215 | Glycyl Radical Enzyme | Family | |
IPR004184 | Pyruvate formate lyase domain | Domain | |
IPR001150 | Glycine radical domain | Domain |