2C9V
Atomic resolution structure of Cu-Zn Human Superoxide dismutase
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d2c9va_ | All beta proteins | Immunoglobulin-like beta-sandwich | Cu,Zn superoxide dismutase-like | Cu,Zn superoxide dismutase-like | Cu,Zn superoxide dismutase, SOD | HUMAN (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
B [auth F] | d2c9vf_ | All beta proteins | Immunoglobulin-like beta-sandwich | Cu,Zn superoxide dismutase-like | Cu,Zn superoxide dismutase-like | Cu,Zn superoxide dismutase, SOD | HUMAN (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2 Family | Cu, Zn superoxide dismutase-like | 8055252 | 4007548 | SCOP2 (2022-06-29) |
A | SCOP2 Superfamily | Cu, Zn superoxide dismutase-like | 8055253 | 3002059 | SCOP2 (2022-06-29) |
B [auth F] | SCOP2B Superfamily | Cu, Zn superoxide dismutase-like | 8055253 | 3002059 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | Sod_Cu | e2c9vA1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Cu,Zn superoxide dismutase-like | F: Sod_Cu | ECOD (1.6) |
B [auth F] | Sod_Cu | e2c9vF1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Cu,Zn superoxide dismutase-like | F: Sod_Cu | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 2.60.40.200 | Mainly Beta | Sandwich | Immunoglobulin-like | Superoxide dismutase, copper/zinc binding domain | CATH (4.3.0) |
B [auth F] | 2.60.40.200 | Mainly Beta | Sandwich | Immunoglobulin-like | Superoxide dismutase, copper/zinc binding domain | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
A, B [auth F] | PF00080 | Copper/zinc superoxide dismutase (SODC) (Sod_Cu) | Copper/zinc superoxide dismutase (SODC) | superoxide dismutases (SODs) catalyse the conversion of superoxide radicals to hydrogen peroxide and molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the human SO ... | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
A, B [auth F] | IPR024134 | Superoxide dismutase (Cu/Zn) / superoxide dismutase copper chaperone | Family |
A, B [auth F] | IPR036423 | Superoxide dismutase-like, copper/zinc binding domain superfamily | Homologous Superfamily |
A, B [auth F] | IPR018152 | Superoxide dismutase, copper/zinc, binding site | Binding Site |
A, B [auth F] | IPR001424 | Superoxide dismutase, copper/zinc binding domain | Domain |
Pharos: Disease Associations Pharos Homepage Annotation
Chains | Drug Target | Associated Disease |
---|---|---|
A, B [auth F] | P00441 | :