2GX1 | pdb_00002gx1

Solution structure and alanine scan of a spider toxin that affects the activation of mammalian sodium channels

External Resource: Annotation

Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: OPM

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF08093	Magi 5 toxic peptide family (Toxin_23)	Magi 5 toxic peptide family	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Neurotoxin magi-5	monoatomic cation transmembrane transporter activity channel regulator activity monoatomic ion channel activity sodium channel activity molecular function inhibitor activity passive transmembrane transporter activity transporter inhibitor activity inorganic molecular entity transmembrane transporter activity molecular function regulator activity inorganic cation transmembrane transporter activity sodium channel regulator activity transporter activity channel inhibitor activity ion channel regulator activity monoatomic cation transmembrane transporter activity channel regulator activity monoatomic ion channel activity sodium channel activity molecular function inhibitor activity passive transmembrane transporter activity transporter inhibitor activity inorganic molecular entity transmembrane transporter activity molecular function regulator activity inorganic cation transmembrane transporter activity sodium channel regulator activity transporter activity channel inhibitor activity ion channel regulator activity ion channel inhibitor activity sodium ion transmembrane transporter activity monoatomic cation channel activity sodium channel inhibitor activity channel activity monoatomic ion transmembrane transporter activity transporter regulator activity metal ion transmembrane transporter activity transmembrane transporter activity toxin activity	-	cellular anatomical structure extracellular region

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR012628	Magi 5 toxic peptide	Family

Membrane Protein Annotation: OPM OPM Database Homepage

Chains	External Link	Type	Class	Superfamily	Family
A	OPM	Monotopic/peripheral	All beta monotopic/peripheral	Omega conotoxin-like knottin	Spider ion channel inhibitory toxins

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.