2IZ3 | pdb_00002iz3

Solution structure of human beta-microseminoprotein

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Pharos: Disease Associations

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PSP94	e2iz3A1	A: few secondary structure elements	X: Fibronectin type I module-like (From Homology)	H: Fibronectin type I module-like	T: VWC domain-related	F: PSP94	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.10.70.10	Mainly Beta	Ribbon	Complement Module	domain 1	CATH (4.3.0)
A	2.20.25.590	Mainly Beta	Single Sheet	N-terminal domain of TfIIb		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF05825	Beta-microseminoprotein (PSP-94) (PSP94)	Beta-microseminoprotein (PSP-94)	This family consists of the mammalian specific protein beta-microseminoprotein. Prostatic secretory protein of 94 amino acids (PSP94), also called beta-microseminoprotein, is a small, nonglycosylated protein, rich in cysteine residues. It was first i ...	This family consists of the mammalian specific protein beta-microseminoprotein. Prostatic secretory protein of 94 amino acids (PSP94), also called beta-microseminoprotein, is a small, nonglycosylated protein, rich in cysteine residues. It was first isolated as a major protein from human seminal plasma [1]. The exact function of this protein is unknown.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	BETA-MICROSEMINOPROTEIN	-	-	cellular anatomical structure extracellular region extracellular space membrane-bounded organelle intracellular organelle intracellular anatomical structure organelle nucleus intracellular membrane-bounded organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR008735	Beta-microseminoprotein	Family

Pharos: Disease Associations Pharos Homepage Annotation

Chains	Drug Target	Associated Disease
A	Pharos: P08118	prostate cancer prostate cancer, hereditary, 13 atopic eczema familial prostate carcinoma pancreatic intraductal papillary-mucinous carcinoma prion disease prostate carcinoma breast cancer lung carcinoma pancreatic intraductal papillary-mucinous neoplasm Prostatic Neoplasms cystic fibrosis nasopharyngeal carcinoma pancreatic intraductal papillary-mucinous neoplasm with low grade dysplasia psoriasis

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.