Annotations: 2KTX

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d2ktxa_	Small proteins	Knottins (small inhibitors, toxins, lectins)	Scorpion toxin-like	Short-chain scorpion toxins	Kaliotoxin (KTX)	(Androctonus mauritanicus mauritanicus ) [TaxId: 6860 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Short-chain scorpion toxins	8025841	4003142	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Scorpion toxin-like	8038220	3000309	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Toxin_2	e2ktxA1	A: few secondary structure elements	X: omega toxin-like	H: omega toxin-related	T: Scorpion toxin-like	F: Toxin_2	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00451	Scorpion short toxin, BmKK2 (Toxin_2)	Scorpion short toxin, BmKK2	Members of this family, which are found in various scorpion toxins, confer potassium channel blocking activity [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	KALIOTOXIN	channel regulator activity ion channel inhibitor activity monoatomic ion channel activity ion channel regulator activity molecular function inhibitor activity passive transmembrane transporter activity transporter inhibitor activity channel activity molecular function regulator activity monoatomic ion transmembrane transporter activity transporter activity transporter regulator activity channel inhibitor activity transmembrane transporter activity channel regulator activity ion channel inhibitor activity monoatomic ion channel activity ion channel regulator activity molecular function inhibitor activity passive transmembrane transporter activity transporter inhibitor activity channel activity molecular function regulator activity monoatomic ion transmembrane transporter activity transporter activity transporter regulator activity channel inhibitor activity transmembrane transporter activity monoatomic cation transmembrane transporter activity potassium ion transmembrane transporter activity potassium channel activity potassium channel regulator activity monoatomic cation channel activity inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity metal ion transmembrane transporter activity toxin activity	-	cellular anatomical structure extracellular region

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR036574	Knottin, scorpion toxin-like superfamily	Homologous Superfamily
A	IPR001947	Scorpion short chain toxin, potassium channel inhibitor	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.