2LX4 | pdb_00002lx4

NMR solution structure of peptide a2N(1-17) from Mus musculus V-ATPase

External Resource: Annotation

Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	V-type proton ATPase 116 kDa subunit a isoform 2	monoatomic cation transmembrane transporter activity proton transmembrane transporter activity primary active transmembrane transporter activity ATPase-coupled transmembrane transporter activity proton-transporting ATPase activity, rotational mechanism ATPase-coupled monoatomic cation transmembrane transporter activity ATP-dependent activity active monoatomic ion transmembrane transporter activity ATPase-coupled ion transmembrane transporter activity active transmembrane transporter activity ATPase activity, coupled to transmembrane movement of ions, rotational mechanism inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity monoatomic ion transmembrane transporter activity transporter activity monoatomic cation transmembrane transporter activity proton transmembrane transporter activity primary active transmembrane transporter activity ATPase-coupled transmembrane transporter activity proton-transporting ATPase activity, rotational mechanism ATPase-coupled monoatomic cation transmembrane transporter activity ATP-dependent activity active monoatomic ion transmembrane transporter activity ATPase-coupled ion transmembrane transporter activity active transmembrane transporter activity ATPase activity, coupled to transmembrane movement of ions, rotational mechanism inorganic molecular entity transmembrane transporter activity inorganic cation transmembrane transporter activity monoatomic ion transmembrane transporter activity transporter activity transmembrane transporter activity	intracellular iron ion homeostasis inorganic ion homeostasis cellular homeostasis chemical homeostasis homeostatic process intracellular monoatomic cation homeostasis monoatomic ion homeostasis intracellular chemical homeostasis monoatomic cation homeostasis intracellular monoatomic ion homeostasis cellular response to stimulus cellular response to chemical stimulus response to stimulus cellular response to oxygen levels intracellular iron ion homeostasis inorganic ion homeostasis cellular homeostasis chemical homeostasis homeostatic process intracellular monoatomic cation homeostasis monoatomic ion homeostasis intracellular chemical homeostasis monoatomic cation homeostasis intracellular monoatomic ion homeostasis cellular response to stimulus cellular response to chemical stimulus response to stimulus cellular response to oxygen levels response to chemical response to oxygen levels response to abiotic stimulus cellular process cellular response to increased oxygen levels response to increased oxygen levels	cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction ATPase dependent transmembrane transport complex protein-containing complex ATPase complex catalytic complex membrane membrane protein complex proton-transporting V-type ATPase complex transporter complex proton-transporting two-sector ATPase complex, proton-transporting domain cellular anatomical structure anchoring junction cell junction focal adhesion cell-substrate junction ATPase dependent transmembrane transport complex protein-containing complex ATPase complex catalytic complex membrane membrane protein complex proton-transporting V-type ATPase complex transporter complex proton-transporting two-sector ATPase complex, proton-transporting domain cation-transporting ATPase complex proton-transporting two-sector ATPase complex transmembrane transporter complex proton-transporting V-type ATPase, V0 domain membrane-bounded organelle intracellular anatomical structure vacuolar proton-transporting V-type ATPase, V0 domain intracellular organelle bounding membrane of organelle vacuolar membrane vacuole intracellular membrane-bounded organelle vacuolar proton-transporting V-type ATPase complex organelle cytoplasm organelle membrane perinuclear region of cytoplasm endosome membrane endosome intracellular vesicle endomembrane system cytoplasmic vesicle membrane vesicle membrane cytoplasmic vesicle vesicle cell periphery plasma membrane acrosomal vesicle secretory granule secretory vesicle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR026028	ATPase, V0 complex, subunit 116kDa, eukaryotic	Family
A	IPR002490	V-type ATPase, V0 complex, 116kDa subunit family	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.