2MEX | pdb_00002mex

Structure of the tetrameric building block of the Salmonella Typhimurium PrgI Type three secretion system needle

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Type III secretion system needle-like	8074333	3000649	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Type III secretion system needle-like	8074333	3000649	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Type III secretion system needle-like	8074333	3000649	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Type III secretion system needle-like	8074333	3000649	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	T3SS_needle_F	e2mexA1	A: alpha bundles	X: Long alpha-hairpin	H: MxiH-like (From Topology)	T: MxiH-like	F: T3SS_needle_F	ECOD (1.6)
B	T3SS_needle_F	e2mexB1	A: alpha bundles	X: Long alpha-hairpin	H: MxiH-like (From Topology)	T: MxiH-like	F: T3SS_needle_F	ECOD (1.6)
C	T3SS_needle_F	e2mexC1	A: alpha bundles	X: Long alpha-hairpin	H: MxiH-like (From Topology)	T: MxiH-like	F: T3SS_needle_F	ECOD (1.6)
D	T3SS_needle_F	e2mexD1	A: alpha bundles	X: Long alpha-hairpin	H: MxiH-like (From Topology)	T: MxiH-like	F: T3SS_needle_F	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF09392	Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF (T3SS_needle_F)	Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Protein PrgI	identical protein binding protein binding binding	protein localization establishment of protein localization cellular localization nitrogen compound transport transport secretion protein secretion by the type III secretion system establishment of protein localization to extracellular region export from cell protein secretion establishment of localization protein localization to extracellular region transmembrane transport localization secretion by cell protein localization establishment of protein localization cellular localization nitrogen compound transport transport secretion protein secretion by the type III secretion system establishment of protein localization to extracellular region export from cell protein secretion establishment of localization protein localization to extracellular region transmembrane transport localization secretion by cell protein transmembrane transport protein transport cellular macromolecule localization macromolecule localization cellular process	cell surface cellular anatomical structure extracellular region protein-containing complex type III protein secretion system complex

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR037203	Type III secretion, needle-protein-like superfamily	Homologous Superfamily
A, B, C, D	IPR021123	Type III secretion, needle-protein-like	Family
A, B, C, D	IPR011841	Type III secretion system, needle protein	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.