Annotations: 2XTS

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Mo-co_dimer	e2xtsA1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: Mo-co_dimer	ECOD (1.6)
A	Oxidored_molyb	e2xtsA2	A: a+b two layers	X: beta-Grasp	H: Ubiquitin-related	T: Sulfite oxidase, middle catalytic domain	F: Oxidored_molyb	ECOD (1.6)
C	Mo-co_dimer	e2xtsC1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: Mo-co_dimer	ECOD (1.6)
C	Oxidored_molyb	e2xtsC2	A: a+b two layers	X: beta-Grasp	H: Ubiquitin-related	T: Sulfite oxidase, middle catalytic domain	F: Oxidored_molyb	ECOD (1.6)
D	Cytochrome_CBB3	e2xtsD1	A: alpha arrays	X: Cytochrome c-like	H: Cytochrome c (From Topology)	T: Cytochrome c	F: Cytochrome_CBB3	ECOD (1.6)
B	Cytochrome_CBB3	e2xtsB1	A: alpha arrays	X: Cytochrome c-like	H: Cytochrome c (From Topology)	T: Cytochrome c	F: Cytochrome_CBB3	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.90.420.10	Alpha Beta	Alpha-Beta Complex	Sulfite Oxidase	Chain A, domain 2	CATH (4.3.0)
A	2.60.40.650	Mainly Beta	Sandwich	Immunoglobulin-like		CATH (4.3.0)
C	3.90.420.10	Alpha Beta	Alpha-Beta Complex	Sulfite Oxidase	Chain A, domain 2	CATH (4.3.0)
C	2.60.40.650	Mainly Beta	Sandwich	Immunoglobulin-like		CATH (4.3.0)
D	1.10.760.10	Mainly Alpha	Orthogonal Bundle	Cytochrome Bc1 Complex	Chain D, domain 2	CATH (4.3.0)
B	1.10.760.10	Mainly Alpha	Orthogonal Bundle	Cytochrome Bc1 Complex	Chain D, domain 2	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, C	PF00174	Oxidoreductase molybdopterin binding domain (Oxidored_molyb)	Oxidoreductase molybdopterin binding domain	This domain is found in a variety of oxidoreductases. This domain binds to a molybdopterin cofactor. Xanthine dehydrogenases, that also bind molybdopterin, have essentially no similarity.	Domain
A, C	PF03404	Mo-co oxidoreductase dimerisation domain (Mo-co_dimer)	Mo-co oxidoreductase dimerisation domain	This domain is found in molybdopterin cofactor (Mo-co) oxidoreductases. It is involved in dimer formation, and has an Ig-fold structure [1].	Domain
B, D	PF13442	Cytochrome C oxidase, cbb3-type, subunit III (Cytochrome_CBB3)	Cytochrome C oxidase, cbb3-type, subunit III	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, C	SULFITE DEHYDROGENASE	cation binding transition metal ion binding molybdenum ion binding ion binding binding metal ion binding small molecule binding oxidoreductase activity, acting on a sulfur group of donors oxidoreductase activity sulfite oxidase activity oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor catalytic activity organic cyclic compound binding molybdopterin cofactor binding cation binding transition metal ion binding molybdenum ion binding ion binding binding metal ion binding small molecule binding oxidoreductase activity, acting on a sulfur group of donors oxidoreductase activity sulfite oxidase activity oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor catalytic activity organic cyclic compound binding molybdopterin cofactor binding tetrapyrrole binding heme binding	sulfur compound metabolic process metabolic process cellular process	-
B, D	CYTOCHROME	binding organic cyclic compound binding tetrapyrrole binding heme binding electron transfer activity cation binding ion binding metal ion binding small molecule binding	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, C	IPR030835	Sulfite dehydrogenase SoxC	Family
A, C	IPR000572	Oxidoreductase, molybdopterin-binding domain	Domain
A, C	IPR014756	Immunoglobulin E-set	Homologous Superfamily
A, C	IPR006311	Twin-arginine translocation pathway, signal sequence	Conserved Site
A, C	IPR005066	Moybdenum cofactor oxidoreductase, dimerisation	Domain
A, C	IPR008335	Eukaryotic molybdopterin oxidoreductase	Family
A, C	IPR036374	Oxidoreductase, molybdopterin-binding domain superfamily	Homologous Superfamily
B, D	IPR036909	Cytochrome c-like domain superfamily	Homologous Superfamily
B, D	IPR009056	Cytochrome c-like domain	Domain
B, D	IPR002327	Cytochrome c, class IA/ IB	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.