3AUP | pdb_00003aup

Crystal structure of Basic 7S globulin from soybean

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3aupa_	All beta proteins	Acid proteases	Acid proteases	automated matches	automated matches	(Glycine max ) [TaxId: 3847 ],	SCOPe (2.08)
B	d3aupb_	All beta proteins	Acid proteases	Acid proteases	automated matches	automated matches	(Glycine max ) [TaxId: 3847 ],	SCOPe (2.08)
C	d3aupc_	All beta proteins	Acid proteases	Acid proteases	automated matches	automated matches	(Glycine max ) [TaxId: 3847 ],	SCOPe (2.08)
D	d3aupd_	All beta proteins	Acid proteases	Acid proteases	automated matches	automated matches	(Glycine max ) [TaxId: 3847 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Acid proteases	8087232	3001059	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Acid proteases	8087232	3001059	SCOP2B (2022-06-29)
C	SCOP2 Family	Pepsin-like	8087231	4002301	SCOP2 (2022-06-29)
C	SCOP2 Superfamily	Acid proteases	8087232	3001059	SCOP2 (2022-06-29)
D	SCOP2B Superfamily	Acid proteases	8087232	3001059	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	TAXi_C	e3aupA1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: acid protease	F: TAXi_C	ECOD (1.6)
A	TAXi_N	e3aupA2	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: acid protease	F: TAXi_N	ECOD (1.6)
B	TAXi_C	e3aupB2	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: acid protease	F: TAXi_C	ECOD (1.6)
B	TAXi_N	e3aupB1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: acid protease	F: TAXi_N	ECOD (1.6)
C	TAXi_C	e3aupC1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: acid protease	F: TAXi_C	ECOD (1.6)
C	TAXi_N	e3aupC2	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: acid protease	F: TAXi_N	ECOD (1.6)
D	TAXi_C	e3aupD2	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: acid protease	F: TAXi_C	ECOD (1.6)
D	TAXi_N	e3aupD1	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: acid protease	F: TAXi_N	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.40.70.10	Mainly Beta	Beta Barrel	Cathepsin D, subunit A	domain 1	CATH (4.3.0)
B	2.40.70.10	Mainly Beta	Beta Barrel	Cathepsin D, subunit A	domain 1	CATH (4.3.0)
C	2.40.70.10	Mainly Beta	Beta Barrel	Cathepsin D, subunit A	domain 1	CATH (4.3.0)
D	2.40.70.10	Mainly Beta	Beta Barrel	Cathepsin D, subunit A	domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF14541	Xylanase inhibitor C-terminal (TAXi_C)	Xylanase inhibitor C-terminal	This domain is found C-terminal in some aspartic proteinases and in xylanase inhibitors. The activity of these proteins is vital for plant-survival as xylanase produced by phytopathogens destroys plant cells. In TAXI-type inhibitors, this domain is i ...	This domain is found C-terminal in some aspartic proteinases and in xylanase inhibitors. The activity of these proteins is vital for plant-survival as xylanase produced by phytopathogens destroys plant cells. In TAXI-type inhibitors, this domain is important for the differences in xylanase specificity [1-3].	Domain
A, B, C, D	PF14543	Xylanase inhibitor N-terminal (TAXi_N)	Xylanase inhibitor N-terminal	This domain is found N-terminal in some aspartic proteinases and in xylanase inhibitors. The activity of these proteins is vital for plant-survival as xylanase produced by phytopathogens destroys plant cells [1-3].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Basic 7S globulin	aspartic-type peptidase activity peptidase activity catalytic activity, acting on a protein hydrolase activity aspartic-type endopeptidase activity catalytic activity endopeptidase activity nutrient reservoir activity identical protein binding protein binding binding	proteolysis metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR032861	Xylanase inhibitor, N-terminal	Domain
A, B, C, D	IPR001461	Aspartic peptidase A1	Family
A, B, C, D	IPR033121	Peptidase family A1 domain	Domain
A, B, C, D	IPR021109	Aspartic peptidase domain superfamily	Homologous Superfamily
A, B, C, D	IPR032799	Xylanase inhibitor, C-terminal	Domain
A, B, C, D	IPR033868	Xylanase inhibitor I-like	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.