3BRJ | pdb_00003brj

Crystal structure of mannitol operon repressor (MtlR) from Vibrio parahaemolyticus RIMD 2210633

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d3brja1	All alpha proteins	MtlR-like	MtlR-like	MtlR-like	Mannitol operon repressor MtlR	(Vibrio parahaemolyticus RIMD 2210633 ) [TaxId: 223926 ],	SCOPe (2.08)
B	d3brjb_	All alpha proteins	MtlR-like	MtlR-like	MtlR-like	Mannitol operon repressor MtlR	(Vibrio parahaemolyticus RIMD 2210633 ) [TaxId: 223926 ],	SCOPe (2.08)
C	d3brjc_	All alpha proteins	MtlR-like	MtlR-like	MtlR-like	Mannitol operon repressor MtlR	(Vibrio parahaemolyticus RIMD 2210633 ) [TaxId: 223926 ],	SCOPe (2.08)
D	d3brjd_	All alpha proteins	MtlR-like	MtlR-like	MtlR-like	Mannitol operon repressor MtlR	(Vibrio parahaemolyticus RIMD 2210633 ) [TaxId: 223926 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	MtlR-like	8027074	4001519	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	MtlR-like	8039453	3001755	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	MtlR-like	8039453	3001755	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	MtlR-like	8039453	3001755	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	MtlR-like	8039453	3001755	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	MtlR	e3brjA1	A: alpha bundles	X: MtlR-like (From Topology)	H: MtlR-like (From Topology)	T: MtlR-like	F: MtlR	ECOD (1.6)
B	MtlR	e3brjB1	A: alpha bundles	X: MtlR-like (From Topology)	H: MtlR-like (From Topology)	T: MtlR-like	F: MtlR	ECOD (1.6)
C	MtlR	e3brjC1	A: alpha bundles	X: MtlR-like (From Topology)	H: MtlR-like (From Topology)	T: MtlR-like	F: MtlR	ECOD (1.6)
D	MtlR	e3brjD1	A: alpha bundles	X: MtlR-like (From Topology)	H: MtlR-like (From Topology)	T: MtlR-like	F: MtlR	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.20.120.330	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)	Nucleotidyltransferases domain 2	CATH (4.3.0)
B	1.20.120.330	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)	Nucleotidyltransferases domain 2	CATH (4.3.0)
C	1.20.120.330	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)	Nucleotidyltransferases domain 2	CATH (4.3.0)
D	1.20.120.330	Mainly Alpha	Up-down Bundle	Four Helix Bundle (Hemerythrin (Met), subunit A)	Nucleotidyltransferases domain 2	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF05068	Mannitol repressor (MtlR)	Mannitol repressor	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Mannitol operon repressor	-	regulation of cellular process negative regulation of biological process RNA metabolic process regulation of primary metabolic process negative regulation of RNA biosynthetic process RNA biosynthetic process nucleobase-containing compound metabolic process DNA-templated transcription nucleic acid biosynthetic process regulation of RNA metabolic process negative regulation of cellular process negative regulation of nucleobase-containing compound metabolic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process regulation of cellular process negative regulation of biological process RNA metabolic process regulation of primary metabolic process negative regulation of RNA biosynthetic process RNA biosynthetic process nucleobase-containing compound metabolic process DNA-templated transcription nucleic acid biosynthetic process regulation of RNA metabolic process negative regulation of cellular process negative regulation of nucleobase-containing compound metabolic process regulation of nucleobase-containing compound metabolic process regulation of RNA biosynthetic process negative regulation of macromolecule metabolic process regulation of biosynthetic process negative regulation of DNA-templated transcription regulation of biological process negative regulation of metabolic process biological regulation primary metabolic process regulation of macromolecule metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process nucleic acid metabolic process regulation of gene expression biosynthetic process negative regulation of biosynthetic process negative regulation of macromolecule biosynthetic process metabolic process cellular process regulation of macromolecule biosynthetic process macromolecule metabolic process regulation of DNA-templated transcription regulation of metabolic process negative regulation of RNA metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR007761	Mannitol repressor MtlR-like	Family
A, B, C, D	IPR038026	MtlR-like superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.