3FO8 | pdb_00003fo8

Crystal structure of the bacteriophage T4 tail sheath protein, protease resistant fragment gp18PR

External Resource: Annotation

Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A [auth D]	18	e3fo8D2	A: beta sandwiches	X: jelly-roll	H: Domain I of tail sheath protein Gp18 (From Topology)	T: Domain I of tail sheath protein Gp18	F: 18	ECOD (1.6)
A [auth D]	Phage_sheath_1N_1	e3fo8D1	A: a+b complex topology	X: Domain II in tail sheath protein Gp18 (From Topology)	H: Domain II in tail sheath protein Gp18 (From Topology)	T: Domain II in tail sheath protein Gp18	F: Phage_sheath_1N_1	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A [auth D]	2.40.10.380	Mainly Beta	Beta Barrel	Thrombin, subunit H		CATH (4.3.0)
A [auth D]	6.10.250.2160	Special	Helix non-globular	Single alpha-helices involved in coiled-coils or other helix-helix interfaces		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A [auth D]	PF17481	Phage tail sheath protein beta-sandwich domain (Phage_sheath_domII)	Phage tail sheath protein beta-sandwich domain	This entry represents a two-layer beta sandwich domain found in a variety of phage tail sheath proteins, referred to as domain II in [4,5]. Domain I and II form the protease-resistant fragment [5].	Domain
A [auth D]	PF22639	Tail sheath protein Gp18-like domain I (Gp18_dom_I)	Tail sheath protein Gp18-like domain I	This entry represents domain I from bacteriophage tail sheath proteins such as Gp18, a protein that surrounds the central non-contractile tail tube of the tail sheath from bacteriophages, which contracts during infection [1,2]. These proteins consist ...	This entry represents domain I from bacteriophage tail sheath proteins such as Gp18, a protein that surrounds the central non-contractile tail tube of the tail sheath from bacteriophages, which contracts during infection [1,2]. These proteins consist of three domains, domains I, II (Pfam:PF17481) and III (Pfam:PF17482). Domains I and II form the protease-resistant fragment [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth D]	Tail sheath protein Gp18	-	symbiont genome ejection through host cell envelope biological process involved in interspecies interaction between organisms symbiont entry into host cell viral process symbiont entry into host viral life cycle symbiont genome ejection through host cell envelope, contractile tail mechanism biological process involved in interaction with host biological process involved in symbiotic interaction	virus tail virion component virus tail, sheath

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A [auth D]	IPR054565	Tail sheath protein Gp18-like, domain I	Domain
A [auth D]	IPR020287	Tail sheath protein, C-terminal domain	Domain
A [auth D]	IPR054564	Tail sheath protein Gp18-like, domain III N-terminal region	Domain
A [auth D]	IPR035089	Tail sheath protein, subtilisin-like domain	Domain
A [auth D]	IPR035326	Phage tail sheath protein-like, beta-sandwich domain	Domain
A [auth D]	IPR052042	Bacteriophage Tail Sheath Structural Protein	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.