4KPN

Plant nucleoside hydrolase - PpNRh1 enzyme

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Nucleoside hydrolase	8080176	4000751	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Nucleoside hydrolase	8080177	3001240	SCOP2 (2022-06-29)
D	SCOP2B Superfamily	Nucleoside hydrolase	8080177	3001240	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Nucleoside hydrolase	8080177	3001240	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	Nucleoside hydrolase	8080177	3001240	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Nucleoside hydrolase	8080177	3001240	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Nucleoside hydrolase	8080177	3001240	SCOP2B (2022-06-29)
F	SCOP2B Superfamily	Nucleoside hydrolase	8080177	3001240	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Nucleoside hydrolase	8080177	3001240	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	IU_nuc_hydro	e4kpnA1	A: a/b three-layered sandwiches	X: Nucleoside hydrolase (From Topology)	H: Nucleoside hydrolase (From Topology)	T: Nucleoside hydrolase	F: IU_nuc_hydro	ECOD (1.6)
D	IU_nuc_hydro	e4kpnD1	A: a/b three-layered sandwiches	X: Nucleoside hydrolase (From Topology)	H: Nucleoside hydrolase (From Topology)	T: Nucleoside hydrolase	F: IU_nuc_hydro	ECOD (1.6)
E	IU_nuc_hydro	e4kpnE1	A: a/b three-layered sandwiches	X: Nucleoside hydrolase (From Topology)	H: Nucleoside hydrolase (From Topology)	T: Nucleoside hydrolase	F: IU_nuc_hydro	ECOD (1.6)
H	IU_nuc_hydro	e4kpnH1	A: a/b three-layered sandwiches	X: Nucleoside hydrolase (From Topology)	H: Nucleoside hydrolase (From Topology)	T: Nucleoside hydrolase	F: IU_nuc_hydro	ECOD (1.6)
B	IU_nuc_hydro	e4kpnB1	A: a/b three-layered sandwiches	X: Nucleoside hydrolase (From Topology)	H: Nucleoside hydrolase (From Topology)	T: Nucleoside hydrolase	F: IU_nuc_hydro	ECOD (1.6)
C	IU_nuc_hydro	e4kpnC1	A: a/b three-layered sandwiches	X: Nucleoside hydrolase (From Topology)	H: Nucleoside hydrolase (From Topology)	T: Nucleoside hydrolase	F: IU_nuc_hydro	ECOD (1.6)
F	IU_nuc_hydro	e4kpnF1	A: a/b three-layered sandwiches	X: Nucleoside hydrolase (From Topology)	H: Nucleoside hydrolase (From Topology)	T: Nucleoside hydrolase	F: IU_nuc_hydro	ECOD (1.6)
G	IU_nuc_hydro	e4kpnG1	A: a/b three-layered sandwiches	X: Nucleoside hydrolase (From Topology)	H: Nucleoside hydrolase (From Topology)	T: Nucleoside hydrolase	F: IU_nuc_hydro	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.90.245.10	Alpha Beta	Alpha-Beta Complex	Inosine-uridine Nucleoside N-ribohydrolase	Chain A	CATH (4.3.0)
D	3.90.245.10	Alpha Beta	Alpha-Beta Complex	Inosine-uridine Nucleoside N-ribohydrolase	Chain A	CATH (4.3.0)
E	3.90.245.10	Alpha Beta	Alpha-Beta Complex	Inosine-uridine Nucleoside N-ribohydrolase	Chain A	CATH (4.3.0)
H	3.90.245.10	Alpha Beta	Alpha-Beta Complex	Inosine-uridine Nucleoside N-ribohydrolase	Chain A	CATH (4.3.0)
B	3.90.245.10	Alpha Beta	Alpha-Beta Complex	Inosine-uridine Nucleoside N-ribohydrolase	Chain A	CATH (4.3.0)
C	3.90.245.10	Alpha Beta	Alpha-Beta Complex	Inosine-uridine Nucleoside N-ribohydrolase	Chain A	CATH (4.3.0)
F	3.90.245.10	Alpha Beta	Alpha-Beta Complex	Inosine-uridine Nucleoside N-ribohydrolase	Chain A	CATH (4.3.0)
G	3.90.245.10	Alpha Beta	Alpha-Beta Complex	Inosine-uridine Nucleoside N-ribohydrolase	Chain A	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E A, B, C, D, E, F, G, H	PF01156	Inosine-uridine preferring nucleoside hydrolase (IU_nuc_hydro)	Inosine-uridine preferring nucleoside hydrolase	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E A, B, C, D, E, F, G, H	Nucleoside N-ribohydrolase 1	protein heterodimerization activity protein binding binding protein dimerization activity hydrolase activity, acting on glycosyl bonds purine nucleosidase activity hydrolase activity hydrolase activity, hydrolyzing N-glycosyl compounds catalytic activity inosine nucleosidase activity UDP-glycosyltransferase activity glycosyltransferase activity transferase activity glucosyltransferase activity protein heterodimerization activity protein binding binding protein dimerization activity hydrolase activity, acting on glycosyl bonds purine nucleosidase activity hydrolase activity hydrolase activity, hydrolyzing N-glycosyl compounds catalytic activity inosine nucleosidase activity UDP-glycosyltransferase activity glycosyltransferase activity transferase activity glucosyltransferase activity hexosyltransferase activity UDP-glucosyltransferase activity cation binding ion binding metal ion binding small molecule binding	carbohydrate derivative catabolic process glycosyl compound metabolic process catabolic process purine nucleoside catabolic process carbohydrate derivative metabolic process primary metabolic process glycosyl compound catabolic process purine-containing compound catabolic process nucleoside metabolic process nucleobase-containing compound catabolic process purine-containing compound metabolic process nucleobase-containing compound metabolic process nucleobase-containing small molecule catabolic process nucleobase-containing small molecule metabolic process nucleoside catabolic process carbohydrate derivative catabolic process glycosyl compound metabolic process catabolic process purine nucleoside catabolic process carbohydrate derivative metabolic process primary metabolic process glycosyl compound catabolic process purine-containing compound catabolic process nucleoside metabolic process nucleobase-containing compound catabolic process purine-containing compound metabolic process nucleobase-containing compound metabolic process nucleobase-containing small molecule catabolic process nucleobase-containing small molecule metabolic process nucleoside catabolic process small molecule metabolic process metabolic process cellular process small molecule catabolic process purine nucleoside metabolic process inosine catabolic process purine ribonucleoside metabolic process inosine metabolic process ribonucleoside catabolic process purine ribonucleoside catabolic process ribonucleoside metabolic process developmental process multicellular organismal process plant organ development plant organ senescence multicellular organism development anatomical structure development leaf development leaf senescence shoot system development phyllome development system development	cellular anatomical structure intracellular anatomical structure cytoplasm cytosol

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E A, B, C, D, E, F, G, H	IPR036452	Ribonucleoside hydrolase-like	Homologous Superfamily
A, B, C, D, E A, B, C, D, E, F, G, H	IPR023186	Inosine/uridine-preferring nucleoside hydrolase	Family
A, B, C, D, E A, B, C, D, E, F, G, H	IPR001910	Inosine/uridine-preferring nucleoside hydrolase domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.