Crystal structure of an immunoreactive 32 kDa antigen PG49 (PG_0181) from Porphyromonas gingivalis W83 at 1.45 A resolution (PSI Community Target, Nakayama)
This family consists of several Porphyromonas gingivalis major fimbrial subunit protein (FimA) sequences. Fimbriae of Porphyromonas gingivalis, a periodontopathogen, play an important role in its adhesion to and invasion of host cells. The fimA genes ...
This family consists of several Porphyromonas gingivalis major fimbrial subunit protein (FimA) sequences. Fimbriae of Porphyromonas gingivalis, a periodontopathogen, play an important role in its adhesion to and invasion of host cells. The fimA genes encoding fimbrillin (FimA), a subunit protein of fimbriae, have been classified into five types, types I to V, based on nucleotide sequences. It has been found that type II FimA can bind to epithelial cells most efficiently through specific host receptors [1]. Human dental plaque is a multispecies microbial biofilm that is associated with two common oral diseases, dental caries and periodontal disease. There is an inter-species contact-dependent communication system between P. gingivalis and S. cristatus that involces the Arc-A enzyme [2].
This domain is found at the C-terminal end of Minor fimbrium tip subunit MfA4 from Porphyromonas gingivalis and similar sequences mainly found in bacteroidales. MfA4 is involved in biofilm formation, adhesion onto host cells and onto other bacteria t ...
This domain is found at the C-terminal end of Minor fimbrium tip subunit MfA4 from Porphyromonas gingivalis and similar sequences mainly found in bacteroidales. MfA4 is involved in biofilm formation, adhesion onto host cells and onto other bacteria that are part of the oral microbiome. This domain adopts a transthyretin-like fold that contains seven core beta-strands arranged in two beta-sheets [1].
