Annotations: 5G4F

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
F [auth P]	SCOP2B Superfamily	Cdc48 domain 2-like	8034906	3000725	SCOP2B (2022-06-29)
F [auth P]	SCOP2B Superfamily	ADC-like	8042536	3001132	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	Cdc48 domain 2-like	8034906	3000725	SCOP2B (2022-06-29)
A	SCOP2B Superfamily	ADC-like	8042536	3001132	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Cdc48 domain 2-like	8034906	3000725	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	ADC-like	8042536	3001132	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	ADC-like	8042536	3001132	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Cdc48 domain 2-like	8034906	3000725	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Cdc48 domain 2-like	8034906	3000725	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	ADC-like	8042536	3001132	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	ADC-like	8042536	3001132	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Cdc48 domain 2-like	8034906	3000725	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
F [auth P]	CDC48_N	e5g4fP3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: double psi	F: CDC48_N	ECOD (1.6)
F [auth P]	CDC48	e5g4fP5	A: alpha arrays	X: Histone-like	H: Histone-related	T: AAA+ ATPase lid domain	F: CDC48	ECOD (1.6)
F [auth P]	Vps4_C_C_1	e5g4fP6	A: alpha arrays	X: Histone-like	H: Histone-related	T: AAA+ ATPase lid domain	F: Vps4_C_C_1	ECOD (1.6)
F [auth P]	CDC48_2	e5g4fP4	A: a+b two layers	X: Cdc48 domain 2-like (From Topology)	H: Cdc48 domain 2-like (From Topology)	T: Cdc48 domain 2-like	F: CDC48_2	ECOD (1.6)
F [auth P]	Sigma54_activat	e5g4fP1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: Sigma54_activat	ECOD (1.6)
A	CDC48_N	e5g4fA3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: double psi	F: CDC48_N	ECOD (1.6)
A	CDC48	e5g4fA5	A: alpha arrays	X: Histone-like	H: Histone-related	T: AAA+ ATPase lid domain	F: CDC48	ECOD (1.6)
A	Vps4_C_C_1	e5g4fA6	A: alpha arrays	X: Histone-like	H: Histone-related	T: AAA+ ATPase lid domain	F: Vps4_C_C_1	ECOD (1.6)
A	CDC48_2	e5g4fA4	A: a+b two layers	X: Cdc48 domain 2-like (From Topology)	H: Cdc48 domain 2-like (From Topology)	T: Cdc48 domain 2-like	F: CDC48_2	ECOD (1.6)
A	Sigma54_activat	e5g4fA1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: Sigma54_activat	ECOD (1.6)
B	CDC48_N	e5g4fB3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: double psi	F: CDC48_N	ECOD (1.6)
B	CDC48	e5g4fB5	A: alpha arrays	X: Histone-like	H: Histone-related	T: AAA+ ATPase lid domain	F: CDC48	ECOD (1.6)
B	Vps4_C_C_1	e5g4fB6	A: alpha arrays	X: Histone-like	H: Histone-related	T: AAA+ ATPase lid domain	F: Vps4_C_C_1	ECOD (1.6)
B	CDC48_2	e5g4fB4	A: a+b two layers	X: Cdc48 domain 2-like (From Topology)	H: Cdc48 domain 2-like (From Topology)	T: Cdc48 domain 2-like	F: CDC48_2	ECOD (1.6)
B	Sigma54_activat	e5g4fB1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: Sigma54_activat	ECOD (1.6)
C	CDC48_N	e5g4fC3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: double psi	F: CDC48_N	ECOD (1.6)
C	CDC48	e5g4fC5	A: alpha arrays	X: Histone-like	H: Histone-related	T: AAA+ ATPase lid domain	F: CDC48	ECOD (1.6)
C	Vps4_C_C_1	e5g4fC6	A: alpha arrays	X: Histone-like	H: Histone-related	T: AAA+ ATPase lid domain	F: Vps4_C_C_1	ECOD (1.6)
C	CDC48_2	e5g4fC4	A: a+b two layers	X: Cdc48 domain 2-like (From Topology)	H: Cdc48 domain 2-like (From Topology)	T: Cdc48 domain 2-like	F: CDC48_2	ECOD (1.6)
C	Sigma54_activat	e5g4fC1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: Sigma54_activat	ECOD (1.6)
D	CDC48_N	e5g4fD3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: double psi	F: CDC48_N	ECOD (1.6)
D	CDC48	e5g4fD5	A: alpha arrays	X: Histone-like	H: Histone-related	T: AAA+ ATPase lid domain	F: CDC48	ECOD (1.6)
D	Vps4_C_C_1	e5g4fD6	A: alpha arrays	X: Histone-like	H: Histone-related	T: AAA+ ATPase lid domain	F: Vps4_C_C_1	ECOD (1.6)
D	CDC48_2	e5g4fD4	A: a+b two layers	X: Cdc48 domain 2-like (From Topology)	H: Cdc48 domain 2-like (From Topology)	T: Cdc48 domain 2-like	F: CDC48_2	ECOD (1.6)
D	Sigma54_activat	e5g4fD1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: Sigma54_activat	ECOD (1.6)
E	CDC48_N	e5g4fE3	A: beta barrels	X: cradle loop barrel	H: RIFT-related	T: double psi	F: CDC48_N	ECOD (1.6)
E	CDC48	e5g4fE5	A: alpha arrays	X: Histone-like	H: Histone-related	T: AAA+ ATPase lid domain	F: CDC48	ECOD (1.6)
E	Vps4_C_C_1	e5g4fE6	A: alpha arrays	X: Histone-like	H: Histone-related	T: AAA+ ATPase lid domain	F: Vps4_C_C_1	ECOD (1.6)
E	CDC48_2	e5g4fE4	A: a+b two layers	X: Cdc48 domain 2-like (From Topology)	H: Cdc48 domain 2-like (From Topology)	T: Cdc48 domain 2-like	F: CDC48_2	ECOD (1.6)
E	Sigma54_activat	e5g4fE1	A: a/b three-layered sandwiches	X: P-loop domains-like	H: P-loop domains-related	T: P-loop containing nucleoside triphosphate hydrolases	F: Sigma54_activat	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D, E, A, B, C, D, E, F [auth P]	PF02933	Cell division protein 48 (CDC48), domain 2 (CDC48_2)	Cell division protein 48 (CDC48), domain 2	This domain has a double psi-beta barrel fold and includes VCP-like ATPase and N-ethylmaleimide sensitive fusion protein N-terminal domains. Both the VAT and NSF N-terminal functional domains consist of two structural domains of which this is at t ...	This domain has a double psi-beta barrel fold and includes VCP-like ATPase and N-ethylmaleimide sensitive fusion protein N-terminal domains. Both the VAT and NSF N-terminal functional domains consist of two structural domains of which this is at the C-terminus. The VAT-N domain found in AAA ATPases Pfam:PF00004 is a substrate 185-residue recognition domain [1].	Domain
A, B, C, D, E, A, B, C, D, E, F [auth P]	PF17862	AAA+ lid domain (AAA_lid_3)	AAA+ lid domain	This entry represents the alpha helical AAA+ lid domain that is found to the C-terminus of AAA domains.	Domain
A, B, C, D, E, A, B, C, D, E, F [auth P]	PF00004	ATPase family associated with various cellular activities (AAA) (AAA)	ATPase family associated with various cellular activities (AAA)	AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes [2].	Domain
A, B, C, D, E, A, B, C, D, E, F [auth P]	PF02359	Cell division protein 48 (CDC48), N-terminal domain (CDC48_N)	Cell division protein 48 (CDC48), N-terminal domain	This domain has a double psi-beta barrel fold and includes VCP-like ATPase and N-ethylmaleimide sensitive fusion protein N-terminal domains. Both the VAT and NSF N-terminal functional domains consist of two structural domains of which this is at t ...	This domain has a double psi-beta barrel fold and includes VCP-like ATPase and N-ethylmaleimide sensitive fusion protein N-terminal domains. Both the VAT and NSF N-terminal functional domains consist of two structural domains of which this is at the N-terminus. The VAT-N domain found in AAA ATPases Pfam:PF00004 is a substrate 185-residue recognition domain [1].	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D, E, A, B, C, D, E, F [auth P]	VCP-LIKE ATPASE	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding pyrophosphatase activity ATP hydrolysis activity ribonucleoside triphosphate phosphatase activity hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides hydrolase activity hydrolase activity, acting on acid anhydrides catalytic activity ATP-dependent activity	-	membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure organelle intracellular membrane-bounded organelle cytoplasm

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D, E, A, B, C, D, E, F [auth P]	IPR029067	CDC48 domain 2-like superfamily	Homologous Superfamily
A, B, C, D, E, A, B, C, D, E, F [auth P]	IPR041569	AAA ATPase, AAA+ lid domain	Domain
A, B, C, D, E, A, B, C, D, E, F [auth P]	IPR004201	CDC48, domain 2	Domain
A, B, C, D, E, A, B, C, D, E, F [auth P]	IPR050168	AAA ATPase domain-containing protein	Family
A, B, C, D, E, A, B, C, D, E, F [auth P]	IPR009010	Aspartate decarboxylase-like domain superfamily	Homologous Superfamily
A, B, C, D, E, A, B, C, D, E, F [auth P]	IPR005938	AAA ATPase, CDC48 family	Family
A, B, C, D, E, A, B, C, D, E, F [auth P]	IPR003960	ATPase, AAA-type, conserved site	Conserved Site
A, B, C, D, E, A, B, C, D, E, F [auth P]	IPR003338	CDC48, N-terminal subdomain	Domain
A, B, C, D, E, A, B, C, D, E, F [auth P]	IPR003593	AAA+ ATPase domain	Domain
A, B, C, D, E, A, B, C, D, E, F [auth P]	IPR003959	ATPase, AAA-type, core	Domain
A, B, C, D, E, A, B, C, D, E, F [auth P]	IPR027417	P-loop containing nucleoside triphosphate hydrolase	Homologous Superfamily