Annotations: 5J6F

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	CM_2	e5j6fB2	A: alpha bundles	X: Chorismate mutase II (From Topology)	H: Chorismate mutase II (From Topology)	T: Chorismate mutase II	F: CM_2	ECOD (1.6)
B	DAHP_synth_1	e5j6fB1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: DAHP_synth_1	ECOD (1.6)
A	CM_2	e5j6fA2	A: alpha bundles	X: Chorismate mutase II (From Topology)	H: Chorismate mutase II (From Topology)	T: Chorismate mutase II	F: CM_2	ECOD (1.6)
A	DAHP_synth_1	e5j6fA1	A: a/b barrels	X: TIM beta/alpha-barrel	H: TIM barrels (From Topology)	T: TIM barrels	F: DAHP_synth_1	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	1.20.59.10	Mainly Alpha	Up-down Bundle	Chorismate Mutase Domain, subunit A	Chorismate mutase	CATH (4.3.0)
B	3.20.20.70	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Aldolase class I	CATH (4.3.0)
A	1.20.59.10	Mainly Alpha	Up-down Bundle	Chorismate Mutase Domain, subunit A	Chorismate mutase	CATH (4.3.0)
A	3.20.20.70	Alpha Beta	Alpha-Beta Barrel	TIM Barrel	Aldolase class I	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF01817	Chorismate mutase type II (CM_2)	Chorismate mutase type II	Chorismate mutase EC:5.4.99.5 catalyses the conversion of chorismate to prephenate in the pathway of tyrosine and phenylalanine biosynthesis. This enzyme is negatively regulated by tyrosine, tryptophan and phenylalanine [2,3].	Domain
A, B	PF00793	DAHP synthetase I family (DAHP_synth_1)	DAHP synthetase I family	Members of this family catalyse the first step in aromatic amino acid biosynthesis from chorismate. E-coli has three related synthetases, which are inhibited by different aromatic amino acids. This family also includes KDSA which has very similar cat ...	Members of this family catalyse the first step in aromatic amino acid biosynthesis from chorismate. E-coli has three related synthetases, which are inhibited by different aromatic amino acids. This family also includes KDSA which has very similar catalytic activity but is involved in the first step of liposaccharide biosynthesis. The enzyme is also part of the shikimate pathway, EC:2.5.1.54.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	3-deoxy-D-arabino-heptulosonate 7-phosphate synthase, chorismate mutase-isozyme 3	isomerase activity chorismate mutase activity catalytic activity intramolecular transferase activity lyase activity carbon-carbon lyase activity aldehyde-lyase activity transferase activity 3-deoxy-7-phosphoheptulonate synthase activity transferase activity, transferring alkyl or aryl (other than methyl) groups cation binding ion binding binding metal ion binding isomerase activity chorismate mutase activity catalytic activity intramolecular transferase activity lyase activity carbon-carbon lyase activity aldehyde-lyase activity transferase activity 3-deoxy-7-phosphoheptulonate synthase activity transferase activity, transferring alkyl or aryl (other than methyl) groups cation binding ion binding binding metal ion binding small molecule binding	aromatic amino acid family biosynthetic process aromatic amino acid metabolic process small molecule biosynthetic process oxoacid metabolic process carboxylic acid metabolic process amino acid metabolic process primary metabolic process organic acid biosynthetic process organic acid metabolic process carboxylic acid biosynthetic process biosynthetic process small molecule metabolic process metabolic process cellular process aromatic amino acid family biosynthetic process aromatic amino acid metabolic process small molecule biosynthetic process oxoacid metabolic process carboxylic acid metabolic process amino acid metabolic process primary metabolic process organic acid biosynthetic process organic acid metabolic process carboxylic acid biosynthetic process biosynthetic process small molecule metabolic process metabolic process cellular process dicarboxylic acid metabolic process chorismate metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR052899	Class-I DAHP synthase	Family
A, B	IPR013785	Aldolase-type TIM barrel	Homologous Superfamily
A, B	IPR006218	DAHP synthetase I/KDSA	Domain
A, B	IPR006268	Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2	Domain
A, B	IPR036979	Chorismate mutase domain superfamily	Homologous Superfamily
A, B	IPR002701	Chorismate mutase II, prokaryotic-type	Domain
A, B	IPR010954	Chorismate mutase, Firmicutes/Deinococcus	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.