5NX6

Crystal structure of 1,8-cineole synthase from Streptomyces clavuligerus in complex with 2-fluoroneryl diphosphate

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d5nx6a1	All alpha proteins	Terpenoid synthases	Terpenoid synthases	automated matches	automated matches	(Streptomyces clavuligerus ) [TaxId: 1901 ],	SCOPe (2.08)
B	d5nx6b1	All alpha proteins	Terpenoid synthases	Terpenoid synthases	automated matches	automated matches	(Streptomyces clavuligerus ) [TaxId: 1901 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Aristolochene/pentalenene synthase	8085687	4001461	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Terpenoid synthases	8085688	3001615	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	Terpenoid synthases	8085688	3001615	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Terpene_synth_C	e5nx6A1	A: alpha bundles	X: Terpenoid synthases (From Topology)	H: Terpenoid synthases (From Topology)	T: Terpenoid synthases	F: Terpene_synth_C	ECOD (1.6)
B	Terpene_synth_C	e5nx6B1	A: alpha bundles	X: Terpenoid synthases (From Topology)	H: Terpenoid synthases (From Topology)	T: Terpenoid synthases	F: Terpene_synth_C	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF19086	Terpene synthase family 2, C-terminal metal binding (Terpene_syn_C_2)	Terpene synthase family 2, C-terminal metal binding	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Pentalenene synthase	cation binding magnesium ion binding ion binding binding metal ion binding small molecule binding carbon-oxygen lyase activity, acting on phosphates lyase activity 1,8-cineole synthase activity catalytic activity carbon-oxygen lyase activity	primary metabolic process phospholipid metabolic process organophosphate metabolic process phosphate-containing compound metabolic process metabolic process cellular process phosphorus metabolic process geranyl diphosphate metabolic process terpenoid metabolic process isoprenoid metabolic process lipid metabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR034686	Terpene cyclase-like 2	Family
A, B	IPR008949	Isoprenoid synthase domain superfamily	Homologous Superfamily
A, B	IPR050225	Terpene_synthase	Unknown

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.