5QB0
OXA-48 IN COMPLEX WITH COMPOUND 35
External Resource: Annotation
- Domain Annotation: SCOP/SCOPe Classification
- Domain Annotation: SCOP2 Classification
- Domain Annotation: ECOD Classification
- Domain Annotation: CATH
- AMR Gene: CARD Annotation
- AMR Gene Family: CARD Annotation
- Protein Family Annotation
- Gene Ontology: Gene Product Annotation
- InterPro: Protein Family Classification
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | d5qb0b_ | Multi-domain proteins (alpha and beta) | beta-lactamase/transpeptidase-like | beta-lactamase/transpeptidase-like | automated matches | automated matches | (Klebsiella pneumoniae ) [TaxId: 573 ], | SCOPe (2.08) |
D | d5qb0d_ | Multi-domain proteins (alpha and beta) | beta-lactamase/transpeptidase-like | beta-lactamase/transpeptidase-like | automated matches | automated matches | (Klebsiella pneumoniae ) [TaxId: 573 ], | SCOPe (2.08) |
A | d5qb0a_ | Multi-domain proteins (alpha and beta) | beta-lactamase/transpeptidase-like | beta-lactamase/transpeptidase-like | automated matches | automated matches | (Klebsiella pneumoniae ) [TaxId: 573 ], | SCOPe (2.08) |
C | d5qb0c_ | Multi-domain proteins (alpha and beta) | beta-lactamase/transpeptidase-like | beta-lactamase/transpeptidase-like | automated matches | automated matches | (Klebsiella pneumoniae ) [TaxId: 573 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
B | SCOP2B Superfamily | beta-lactamase/transpeptidase-like | 8074295 | 3001604 | SCOP2B (2022-06-29) |
D | SCOP2B Superfamily | beta-lactamase/transpeptidase-like | 8074295 | 3001604 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | beta-lactamase/transpeptidase-like | 8074295 | 3001604 | SCOP2B (2022-06-29) |
C | SCOP2B Superfamily | beta-lactamase/transpeptidase-like | 8074295 | 3001604 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | Transpeptidase_1st | e5qb0B1 | A: alpha complex topology | X: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology) | H: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology) | T: alpha-helical domain in beta-lactamase/transpeptidase-like proteins | F: Transpeptidase_1st | ECOD (1.6) |
B | Transpeptidase_2nd_1 | e5qb0B2 | A: a+b three layers | X: Profilin-like | H: a+b domain in beta-lactamase/transpeptidase-like proteins (From Topology) | T: a+b domain in beta-lactamase/transpeptidase-like proteins | F: Transpeptidase_2nd_1 | ECOD (1.6) |
D | Transpeptidase_1st | e5qb0D2 | A: alpha complex topology | X: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology) | H: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology) | T: alpha-helical domain in beta-lactamase/transpeptidase-like proteins | F: Transpeptidase_1st | ECOD (1.6) |
D | Transpeptidase_2nd_1 | e5qb0D1 | A: a+b three layers | X: Profilin-like | H: a+b domain in beta-lactamase/transpeptidase-like proteins (From Topology) | T: a+b domain in beta-lactamase/transpeptidase-like proteins | F: Transpeptidase_2nd_1 | ECOD (1.6) |
A | Transpeptidase_1st | e5qb0A2 | A: alpha complex topology | X: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology) | H: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology) | T: alpha-helical domain in beta-lactamase/transpeptidase-like proteins | F: Transpeptidase_1st | ECOD (1.6) |
A | Transpeptidase_2nd_1 | e5qb0A1 | A: a+b three layers | X: Profilin-like | H: a+b domain in beta-lactamase/transpeptidase-like proteins (From Topology) | T: a+b domain in beta-lactamase/transpeptidase-like proteins | F: Transpeptidase_2nd_1 | ECOD (1.6) |
C | Transpeptidase_1st | e5qb0C1 | A: alpha complex topology | X: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology) | H: alpha-helical domain in beta-lactamase/transpeptidase-like proteins (From Topology) | T: alpha-helical domain in beta-lactamase/transpeptidase-like proteins | F: Transpeptidase_1st | ECOD (1.6) |
C | Transpeptidase_2nd_1 | e5qb0C2 | A: a+b three layers | X: Profilin-like | H: a+b domain in beta-lactamase/transpeptidase-like proteins (From Topology) | T: a+b domain in beta-lactamase/transpeptidase-like proteins | F: Transpeptidase_2nd_1 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
B | 3.40.710.10 | Alpha Beta | 3-Layer(aba) Sandwich | Beta-lactamase | DD-peptidase/beta-lactamase superfamily | CATH (4.3.0) |
D | 3.40.710.10 | Alpha Beta | 3-Layer(aba) Sandwich | Beta-lactamase | DD-peptidase/beta-lactamase superfamily | CATH (4.3.0) |
A | 3.40.710.10 | Alpha Beta | 3-Layer(aba) Sandwich | Beta-lactamase | DD-peptidase/beta-lactamase superfamily | CATH (4.3.0) |
C | 3.40.710.10 | Alpha Beta | 3-Layer(aba) Sandwich | Beta-lactamase | DD-peptidase/beta-lactamase superfamily | CATH (4.3.0) |
AMR Gene: CARD Annotation CARD Database Homepage
Chains | Accession | Short Name | Description | Provenance Source (Version) |
---|---|---|---|---|
ARO:3001782 | OXA-48 | OXA-48 is a beta-lactamase found in Klebsiella pneumoniae. | CARD (3.3.0) |
AMR Gene Family: CARD Annotation CARD Database Homepage
Chains | Accession | Gene Family | Drug Class | Resistance Machanism | Provenance Source (Version) |
---|---|---|---|---|---|
ARO:3007721 | OXA-48-like beta-lactamase | carbapenem, penam | antibiotic inactivation | CARD (3.3.0) |
Protein Family Annotation Pfam Database Homepage
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR012338 | Beta-lactamase/transpeptidase-like | Homologous Superfamily | |
IPR001460 | Penicillin-binding protein, transpeptidase | Domain | |
IPR050515 | Bacterial Transpeptidases and Beta-Lactamases | Family | |
IPR002137 | Beta-lactamase, class-D active site | Active Site |