Structure of the Tn1549 transposon Integrase (aa 82-397, R225K) in complex with a circular intermediate DNA (CI6a-DNA)
Domain Annotation: ECOD Classification ECOD Database Homepage
| Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
|---|---|---|---|---|---|---|---|---|
| A | Phage_integrase_C | e6en1A2 | A: alpha arrays | X: HTH | H: HTH | T: DNA breaking-rejoining enzymes | F: Phage_integrase_C | ECOD (1.6) |
| A | Phage_integrase_N | e6en1A3 | A: alpha arrays | X: HTH | H: HTH | T: DNA breaking-rejoining enzymes | F: Phage_integrase_N | ECOD (1.6) |
| A | Phage_int_SAM_3 | e6en1A1 | A: alpha arrays | X: lambda integrase-N-like | H: lambda integrase-N (From Topology) | T: lambda integrase-N | F: Phage_int_SAM_3 | ECOD (1.6) |
| D [auth B] | Phage_integrase_C | e6en1B2 | A: alpha arrays | X: HTH | H: HTH | T: DNA breaking-rejoining enzymes | F: Phage_integrase_C | ECOD (1.6) |
| D [auth B] | Phage_integrase_N | e6en1B3 | A: alpha arrays | X: HTH | H: HTH | T: DNA breaking-rejoining enzymes | F: Phage_integrase_N | ECOD (1.6) |
| D [auth B] | Phage_int_SAM_3 | e6en1B1 | A: alpha arrays | X: lambda integrase-N-like | H: lambda integrase-N (From Topology) | T: lambda integrase-N | F: Phage_int_SAM_3 | ECOD (1.6) |
Protein Family Annotation Pfam Database Homepage
| Chains | Accession | Name | Description | Comments | Source |
|---|---|---|---|---|---|
| A, D [auth B] | PF00589 | Phage integrase family (Phage_integrase) | Phage integrase family | - | Family |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
| Chains | Polymer | Molecular Function | Biological Process | Cellular Component |
|---|---|---|---|---|
| A, D [auth B] | Int protein | - | ||
| B [auth C] | DNA (45-MER) | - | - | - |
| C [auth D] | DNA (45-MER) | - | - | - |
InterPro: Protein Family Classification InterPro Database Homepage
| Chains | Accession | Name | Type |
|---|---|---|---|
| A, D [auth B] | IPR011010 | DNA breaking-rejoining enzyme, catalytic core | Homologous Superfamily |
| A, D [auth B] | IPR010998 | Integrase/recombinase, N-terminal | Homologous Superfamily |
| A, D [auth B] | IPR050090 | Bacterial tyrosine recombinase XerC/XerD complex | Family |
| A, D [auth B] | IPR044068 | Core-binding (CB) domain | Domain |
| A, D [auth B] | IPR004191 | Integrase, Tn916-type, N-terminal DNA binding | Domain |
| A, D [auth B] | IPR002104 | Integrase, catalytic domain | Domain |
| A, D [auth B] | IPR013762 | Integrase-like, catalytic domain superfamily | Homologous Superfamily |
| A, D [auth B] | IPR016177 | DNA-binding domain superfamily | Homologous Superfamily |
