6HOH
Structure of VPS34 LIR motif (S249E) bound to GABARAP
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d6hoha_ | Alpha and beta proteins (a+b) | beta-Grasp (ubiquitin-like) | Ubiquitin-like | automated matches | automated matches | Human (Homo sapiens ) [TaxId: 9606 ], Human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
C | d6hohc_ | Alpha and beta proteins (a+b) | beta-Grasp (ubiquitin-like) | Ubiquitin-like | automated matches | automated matches | Human (Homo sapiens ) [TaxId: 9606 ], Human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
D | d6hohd_ | Alpha and beta proteins (a+b) | beta-Grasp (ubiquitin-like) | Ubiquitin-like | automated matches | automated matches | Human (Homo sapiens ) [TaxId: 9606 ], Human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
B | d6hohb_ | Alpha and beta proteins (a+b) | beta-Grasp (ubiquitin-like) | Ubiquitin-like | automated matches | automated matches | Human (Homo sapiens ) [TaxId: 9606 ], Human (Homo sapiens ) [TaxId: 9606 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2B Superfamily | Ubiquitin-like | 8040431 | 3000157 | SCOP2B (2022-06-29) |
C | SCOP2B Superfamily | Ubiquitin-like | 8040431 | 3000157 | SCOP2B (2022-06-29) |
D | SCOP2B Superfamily | Ubiquitin-like | 8040431 | 3000157 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | Ubiquitin-like | 8040431 | 3000157 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | Atg8 | e6hohA1 | A: a+b two layers | X: beta-Grasp | H: Ubiquitin-related | T: Ubiquitin-like | F: Atg8 | ECOD (1.6) |
C | Atg8 | e6hohC1 | A: a+b two layers | X: beta-Grasp | H: Ubiquitin-related | T: Ubiquitin-like | F: Atg8 | ECOD (1.6) |
B | Atg8 | e6hohB1 | A: a+b two layers | X: beta-Grasp | H: Ubiquitin-related | T: Ubiquitin-like | F: Atg8 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 3.10.20.90 | Alpha Beta | Roll | Ubiquitin-like (UB roll) | Phosphatidylinositol 3-kinase Catalytic Subunit | CATH (utative) |
C | 3.10.20.90 | Alpha Beta | Roll | Ubiquitin-like (UB roll) | Phosphatidylinositol 3-kinase Catalytic Subunit | CATH (utative) |
D | 3.10.20.90 | Alpha Beta | Roll | Ubiquitin-like (UB roll) | Phosphatidylinositol 3-kinase Catalytic Subunit | CATH (utative) |
B | 3.10.20.90 | Alpha Beta | Roll | Ubiquitin-like (UB roll) | Phosphatidylinositol 3-kinase Catalytic Subunit | CATH (utative) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF02991 | Autophagy protein Atg8 ubiquitin like (ATG8) | Autophagy protein Atg8 ubiquitin like | Light chain 3 is proposed to function primarily as a subunit of microtubule associated proteins 1A and 1B and that its expression may regulate microtubule binding activity [1]. Autophagy is generally known as a process involved in the degradation of ... | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR015433 | Phosphatidylinositol kinase | Family | |
IPR016024 | Armadillo-type fold | Homologous Superfamily | |
IPR008290 | Phosphatidylinositol 3-kinase, Vps34 type | Family | |
IPR002420 | C2 phosphatidylinositol 3-kinase-type domain | Domain | |
IPR018936 | Phosphatidylinositol 3/4-kinase, conserved site | Conserved Site | |
IPR000403 | Phosphatidylinositol 3-/4-kinase, catalytic domain | Domain | |
IPR001263 | Phosphoinositide 3-kinase, accessory (PIK) domain | Domain | |
IPR042236 | Phosphoinositide 3-kinase, accessory (PIK) domain superfamily | Homologous Superfamily | |
IPR036940 | Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily | Homologous Superfamily | |
IPR011009 | Protein kinase-like domain superfamily | Homologous Superfamily | |
IPR035892 | C2 domain superfamily | Homologous Superfamily | |
IPR004241 | Autophagy protein Atg8 ubiquitin-like | Family | |
IPR029071 | Ubiquitin-like domain superfamily | Homologous Superfamily |