Annotations: 6JNF

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Porin_3	e6jnfA1	A: beta barrels	X: Outer membrane meander beta-barrels	H: Porins	T: Porin	F: Porin_3	ECOD (1.6)
F	Porin_3	e6jnfF1	A: beta barrels	X: Outer membrane meander beta-barrels	H: Porins	T: Porin	F: Porin_3	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, F	PF01459	Eukaryotic porin (Porin_3)	Eukaryotic porin	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, F	Mitochondrial import receptor subunit TOM40	wide pore channel activity passive transmembrane transporter activity channel activity porin activity transporter activity transmembrane transporter activity macromolecule transmembrane transporter activity protein transporter activity protein transmembrane transporter activity	localization transport monoatomic ion transport establishment of localization protein localization establishment of protein localization cellular localization nitrogen compound transport establishment of protein localization to mitochondrial membrane protein targeting mitochondrial membrane organization cellular component organization outer mitochondrial membrane organization cellular macromolecule localization localization transport monoatomic ion transport establishment of localization protein localization establishment of protein localization cellular localization nitrogen compound transport establishment of protein localization to mitochondrial membrane protein targeting mitochondrial membrane organization cellular component organization outer mitochondrial membrane organization cellular macromolecule localization establishment of localization in cell cellular component organization or biogenesis mitochondrial transport mitochondrion organization membrane organization establishment of protein localization to membrane protein insertion into mitochondrial outer membrane intracellular transport localization within membrane protein localization to membrane organelle organization establishment of protein localization to organelle protein transport macromolecule localization protein localization to organelle protein localization to mitochondrion protein targeting to mitochondrion cellular process establishment of protein localization to mitochondrion intracellular protein transport protein transmembrane import into intracellular organelle protein import into mitochondrial matrix protein transmembrane transport mitochondrial transmembrane transport transmembrane transport import into the mitochondrion	membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure mitochondrion organelle cytoplasm intracellular membrane-bounded organelle mitochondrial protein-containing complex protein-containing complex mitochondrial membrane outer mitochondrial membrane protein complex membrane membrane protein complex membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure mitochondrion organelle cytoplasm intracellular membrane-bounded organelle mitochondrial protein-containing complex protein-containing complex mitochondrial membrane outer mitochondrial membrane protein complex membrane membrane protein complex organelle outer membrane organelle envelope bounding membrane of organelle mitochondrial envelope mitochondrial outer membrane mitochondrial outer membrane translocase complex outer membrane organelle membrane cytosol pore complex mitochondrial intermembrane space membrane-enclosed lumen intracellular organelle lumen organelle envelope lumen organelle lumen
B, G	Mitochondrial import receptor subunit TOM7	-	protein localization establishment of protein localization cellular localization nitrogen compound transport transport establishment of protein localization to mitochondrial membrane protein targeting mitochondrial membrane organization cellular component organization outer mitochondrial membrane organization localization cellular macromolecule localization establishment of localization in cell cellular component organization or biogenesis protein localization establishment of protein localization cellular localization nitrogen compound transport transport establishment of protein localization to mitochondrial membrane protein targeting mitochondrial membrane organization cellular component organization outer mitochondrial membrane organization localization cellular macromolecule localization establishment of localization in cell cellular component organization or biogenesis mitochondrial transport mitochondrion organization membrane organization establishment of protein localization to membrane protein insertion into mitochondrial outer membrane intracellular transport localization within membrane protein localization to membrane establishment of localization organelle organization establishment of protein localization to organelle protein transport macromolecule localization protein localization to organelle protein localization to mitochondrion protein targeting to mitochondrion cellular process establishment of protein localization to mitochondrion intracellular protein transport protein transmembrane import into intracellular organelle protein import into mitochondrial matrix protein transmembrane transport mitochondrial transmembrane transport transmembrane transport import into the mitochondrion	membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure mitochondrion organelle cytoplasm intracellular membrane-bounded organelle mitochondrial membrane membrane organelle outer membrane organelle envelope bounding membrane of organelle mitochondrial envelope membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure mitochondrion organelle cytoplasm intracellular membrane-bounded organelle mitochondrial membrane membrane organelle outer membrane organelle envelope bounding membrane of organelle mitochondrial envelope mitochondrial outer membrane outer membrane organelle membrane mitochondrial protein-containing complex protein-containing complex outer mitochondrial membrane protein complex membrane protein complex mitochondrial outer membrane translocase complex
C, H	Mitochondrial import receptor subunit TOM22	-	protein localization establishment of protein localization cellular localization nitrogen compound transport transport establishment of protein localization to mitochondrial membrane protein targeting mitochondrial membrane organization cellular component organization outer mitochondrial membrane organization localization cellular macromolecule localization establishment of localization in cell cellular component organization or biogenesis protein localization establishment of protein localization cellular localization nitrogen compound transport transport establishment of protein localization to mitochondrial membrane protein targeting mitochondrial membrane organization cellular component organization outer mitochondrial membrane organization localization cellular macromolecule localization establishment of localization in cell cellular component organization or biogenesis mitochondrial transport mitochondrion organization membrane organization establishment of protein localization to membrane protein insertion into mitochondrial outer membrane intracellular transport localization within membrane protein localization to membrane establishment of localization organelle organization establishment of protein localization to organelle protein transport macromolecule localization protein localization to organelle protein localization to mitochondrion protein targeting to mitochondrion cellular process establishment of protein localization to mitochondrion intracellular protein transport protein transmembrane import into intracellular organelle protein import into mitochondrial matrix protein transmembrane transport mitochondrial transmembrane transport transmembrane transport import into the mitochondrion	membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure mitochondrion organelle cytoplasm intracellular membrane-bounded organelle mitochondrial membrane membrane organelle outer membrane organelle envelope bounding membrane of organelle mitochondrial envelope membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure mitochondrion organelle cytoplasm intracellular membrane-bounded organelle mitochondrial membrane membrane organelle outer membrane organelle envelope bounding membrane of organelle mitochondrial envelope mitochondrial outer membrane outer membrane organelle membrane mitochondrial protein-containing complex protein-containing complex outer mitochondrial membrane protein complex membrane protein complex mitochondrial outer membrane translocase complex
D, I	Mitochondrial import receptor subunit TOM5	-	protein localization establishment of protein localization cellular localization nitrogen compound transport transport establishment of protein localization to mitochondrial membrane protein targeting mitochondrial membrane organization cellular component organization outer mitochondrial membrane organization localization cellular macromolecule localization establishment of localization in cell cellular component organization or biogenesis protein localization establishment of protein localization cellular localization nitrogen compound transport transport establishment of protein localization to mitochondrial membrane protein targeting mitochondrial membrane organization cellular component organization outer mitochondrial membrane organization localization cellular macromolecule localization establishment of localization in cell cellular component organization or biogenesis mitochondrial transport mitochondrion organization membrane organization establishment of protein localization to membrane protein insertion into mitochondrial outer membrane intracellular transport localization within membrane protein localization to membrane establishment of localization organelle organization establishment of protein localization to organelle protein transport macromolecule localization protein localization to organelle protein localization to mitochondrion protein targeting to mitochondrion cellular process establishment of protein localization to mitochondrion intracellular protein transport transmembrane transport protein transmembrane transport protein-containing complex organization cellular component biogenesis cellular component assembly protein-containing complex assembly mitochondrial outer membrane translocase complex assembly	membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure mitochondrion organelle cytoplasm intracellular membrane-bounded organelle mitochondrial membrane membrane organelle outer membrane organelle envelope bounding membrane of organelle mitochondrial envelope membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure mitochondrion organelle cytoplasm intracellular membrane-bounded organelle mitochondrial membrane membrane organelle outer membrane organelle envelope bounding membrane of organelle mitochondrial envelope mitochondrial outer membrane outer membrane organelle membrane mitochondrial protein-containing complex protein-containing complex outer mitochondrial membrane protein complex membrane protein complex mitochondrial outer membrane translocase complex
E, J	Mitochondrial import receptor subunit TOM6	-	protein localization establishment of protein localization cellular localization nitrogen compound transport transport establishment of protein localization to mitochondrial membrane protein targeting mitochondrial membrane organization cellular component organization outer mitochondrial membrane organization localization cellular macromolecule localization establishment of localization in cell cellular component organization or biogenesis protein localization establishment of protein localization cellular localization nitrogen compound transport transport establishment of protein localization to mitochondrial membrane protein targeting mitochondrial membrane organization cellular component organization outer mitochondrial membrane organization localization cellular macromolecule localization establishment of localization in cell cellular component organization or biogenesis mitochondrial transport mitochondrion organization membrane organization establishment of protein localization to membrane protein insertion into mitochondrial outer membrane intracellular transport localization within membrane protein localization to membrane establishment of localization organelle organization establishment of protein localization to organelle protein transport macromolecule localization protein localization to organelle protein localization to mitochondrion protein targeting to mitochondrion cellular process establishment of protein localization to mitochondrion intracellular protein transport protein transmembrane import into intracellular organelle protein import into mitochondrial matrix protein transmembrane transport mitochondrial transmembrane transport transmembrane transport import into the mitochondrion protein-containing complex organization cellular component biogenesis cellular component assembly protein-containing complex assembly mitochondrial outer membrane translocase complex assembly	membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure mitochondrion organelle cytoplasm intracellular membrane-bounded organelle mitochondrial membrane membrane organelle outer membrane organelle envelope bounding membrane of organelle mitochondrial envelope membrane-bounded organelle intracellular organelle cellular anatomical structure intracellular anatomical structure mitochondrion organelle cytoplasm intracellular membrane-bounded organelle mitochondrial membrane membrane organelle outer membrane organelle envelope bounding membrane of organelle mitochondrial envelope mitochondrial outer membrane outer membrane organelle membrane mitochondrial protein-containing complex protein-containing complex outer mitochondrial membrane protein complex membrane protein complex mitochondrial outer membrane translocase complex

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, F	IPR005686	Mitochondrial import receptor subunit Tom40, fungi	Family
A, F	IPR023614	Porin domain superfamily	Homologous Superfamily
A, F	IPR037930	Tom40	Family
A, F	IPR027246	Eukaryotic porin/Tom40	Family
B, G	IPR012621	Mitochondrial import receptor subunit TOM7	Family
C, H	IPR005683	Mitochondrial import receptor subunit Tom22	Family
C, H	IPR020951	Mitochondrial import receptor subunit Tom22, fungi	Family
D, I	IPR019603	Mitochondrial outer membrane translocase complex, subunit Tom5	Family
E, J	IPR020266	Mitochondrial import receptor subunit Tom6	Family

Membrane Protein Annotation: OPM OPM Database Homepage

Chains	External Link	Type	Class	Superfamily	Family
A, B, C, D, E A, B, C, D, E, F, G, H, I, J	OPM	Transmembrane	Beta-barrel transmembrane	Mitochondrial and plastid porins	Tom40 family (n=19,S=20)

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

Chains	External Link	Comment
A, B, C, D, E A, B, C, D, E, F, G, H, I, J	PDBTM	Annotated as membrane protein by PDBTM

Membrane Protein Annotation: mpstruc mpstruc Database Homepage

Chains	Resource Link	Group	Subgroup	Protein
A, B, C, D, E A, B, C, D, E, F, G, H, I, J	mpstruc	TRANSMEMBRANE PROTEINS: BETA-BARREL	Mitochondrial Outer Membrane Beta Barrel Proteins	translocase of the outer mitochondrial membrane (TOM) complex

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.