6RUT

Mycoplasma Genitalium Heterodimer Nap Complex (P140-P110 globular)

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: mpstruc

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
E	UNK_F_TYPE	e6rutE1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 7-bladed	F: UNK_F_TYPE	ECOD (1.6)
A	UNK_F_TYPE	e6rutA1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 7-bladed	F: UNK_F_TYPE	ECOD (1.6)
C	UNK_F_TYPE	e6rutC1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 7-bladed	F: UNK_F_TYPE	ECOD (1.6)
G	UNK_F_TYPE	e6rutG1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 7-bladed	F: UNK_F_TYPE	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, C, E, G	PF05220	MgpC adhesin (MgpC)	MgpC adhesin	-	Repeat
B, D, F, H	PF12378	Mycoplasma adhesin P1, N-terminal (P1_N)	Mycoplasma adhesin P1, N-terminal	-	Repeat
B, D, F, H	PF03257	Mycoplasma adhesin P1, C-terminal (Adhesin_P1_C)	Mycoplasma adhesin P1, C-terminal	This domain is found towards the C-terminal of adhesins from Mycoplasmas, such as adhesin P1, first identified as the major determinant for cytoadherence and gliding motility in M. pneumoniae. P1 forms a transmembrane adhesion complex with P40/P90, c ...	This domain is found towards the C-terminal of adhesins from Mycoplasmas, such as adhesin P1, first identified as the major determinant for cytoadherence and gliding motility in M. pneumoniae. P1 forms a transmembrane adhesion complex with P40/P90, called 'Nap', which mediates motility and infectivity in these organisms. The C-terminal domain is smaller than the large N-terminal domain and is mostly conserved [1,2]. It is followed by a transmembrane domain and acts as a stalk connecting the large N-terminal domain with the outer surface of the cell membranes [2,3]. P1 N-terminal domain is highly variable (Pfam:PF12378).	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, C, E, G	Mgp-operon protein 3	-	cell adhesion cellular process	cell periphery cellular anatomical structure plasma membrane membrane
B, D, F, H	Adhesin P1	-	biological process involved in interspecies interaction between organisms adhesion of symbiont to host cell adhesion of symbiont to host adhesion of symbiont to microvasculature biological process involved in interaction with host biological process involved in symbiotic interaction	cell periphery cellular anatomical structure plasma membrane membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, C, E, G	IPR045839	Mgp-operon protein 3, C-terminal domain	Domain
A, C, E, G	IPR007885	MgpC adhesin	Family
B, D, F, H	IPR022400	Adhesin P1	Family
B, D, F, H	IPR004940	Adhesin P1, C-terminal domain	Domain
B, D, F, H	IPR022116	Adhesin P1, N-terminal	Domain

Membrane Protein Annotation: mpstruc mpstruc Database Homepage

Chains	Resource Link	Group	Subgroup	Protein
A, B, C, D, E A, B, C, D, E, F, G, H	mpstruc	MONOTOPIC MEMBRANE PROTEINS	Cell Adhesion Molecules	P140-P110 Nap adhesion complex

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.