6SR6 | pdb_00006sr6

Crystal structure of the RAC core with a pseudo substrate bound to Ssz1 SBD

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Ssz1_peptide-bd	e6sr6A2	A: beta sandwiches	X: Heat shock protein 70kD (HSP70), peptide-binding domain (From Topology)	H: Heat shock protein 70kD (HSP70), peptide-binding domain (From Topology)	T: Heat shock protein 70kD (HSP70), peptide-binding domain	F: Ssz1_peptide-bd	ECOD (1.6)
A	HSP70_1st	e6sr6A3	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: HSP70_1st	ECOD (1.6)
A	FtsA	e6sr6A1	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: FtsA	ECOD (1.6)
C	Ssz1_peptide-bd	e6sr6C3	A: beta sandwiches	X: Heat shock protein 70kD (HSP70), peptide-binding domain (From Topology)	H: Heat shock protein 70kD (HSP70), peptide-binding domain (From Topology)	T: Heat shock protein 70kD (HSP70), peptide-binding domain	F: Ssz1_peptide-bd	ECOD (1.6)
C	HSP70_1st	e6sr6C1	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: HSP70_1st	ECOD (1.6)
C	FtsA	e6sr6C2	A: mixed a+b and a/b	X: Ribonuclease H-like	H: Ribonuclease H-like (From Topology)	T: Ribonuclease H-like	F: FtsA	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, C	PF00012	Hsp70 protein (HSP70)	Hsp70 protein	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, C	Putative heat shock protein	binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding binding adenyl ribonucleotide binding nucleotide binding purine ribonucleotide binding purine ribonucleoside triphosphate binding nucleoside phosphate binding ion binding purine nucleotide binding anion binding adenyl nucleotide binding ATP binding heterocyclic compound binding carbohydrate derivative binding ribonucleotide binding small molecule binding ATP-dependent protein folding chaperone protein folding chaperone ATP-dependent activity	-	cellular anatomical structure intracellular anatomical structure cytoplasm cytosol membrane-bounded organelle intracellular organelle organelle nucleus intracellular membrane-bounded organelle
B, D	Putative ribosome associated protein	protein binding binding Hsp70 protein binding protein-folding chaperone binding heat shock protein binding ribonucleoprotein complex binding protein-containing complex binding ribosome binding	primary metabolic process gene expression macromolecule biosynthetic process protein maturation protein folding biosynthetic process 'de novo' cotranslational protein folding metabolic process cellular process protein metabolic process macromolecule metabolic process 'de novo' protein folding biological regulation regulation of biological quality primary metabolic process gene expression macromolecule biosynthetic process protein maturation protein folding biosynthetic process 'de novo' cotranslational protein folding metabolic process cellular process protein metabolic process macromolecule metabolic process 'de novo' protein folding biological regulation regulation of biological quality regulation of translational fidelity	cellular anatomical structure intracellular anatomical structure cytoplasm cytosol

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, C	IPR013126	Heat shock protein 70 family	Family
A, C	IPR043129	ATPase, nucleotide binding domain	Homologous Superfamily
B, D	IPR054076	Zuotin-like, zuotin homology domain	Domain
B, D	IPR001623	DnaJ domain	Domain
B, D	IPR044634	J-protein Zuotin/DnaJC2	Family
B, D	IPR032003	Ribosome-associated complex head domain	Domain
B, D	IPR042569	Ribosome-associated complex head domain superfamily	Homologous Superfamily
B, D	IPR036869	Chaperone J-domain superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.