7T8G
G93A mutant of human SOD1 bound with MR6-8-2 in P21 space group
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | Sod_Cu | e7t8gA1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Cu,Zn superoxide dismutase-like | F: Sod_Cu | ECOD (1.6) |
B [auth F] | Sod_Cu | e7t8gF1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Cu,Zn superoxide dismutase-like | F: Sod_Cu | ECOD (1.6) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
A, B [auth F] | PF00080 | Copper/zinc superoxide dismutase (SODC) (Sod_Cu) | Copper/zinc superoxide dismutase (SODC) | superoxide dismutases (SODs) catalyse the conversion of superoxide radicals to hydrogen peroxide and molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the human SO ... | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
A, B [auth F] | IPR024134 | Superoxide dismutase (Cu/Zn) / superoxide dismutase copper chaperone | Family |
A, B [auth F] | IPR036423 | Superoxide dismutase-like, copper/zinc binding domain superfamily | Homologous Superfamily |
A, B [auth F] | IPR018152 | Superoxide dismutase, copper/zinc, binding site | Binding Site |
A, B [auth F] | IPR001424 | Superoxide dismutase, copper/zinc binding domain | Domain |
Pharos: Disease Associations Pharos Homepage Annotation
Chains | Drug Target | Associated Disease |
---|---|---|
A, B [auth F] | P00441 | :