8BK2

Chain	Chain Class	Chain Subclass	Chain Type	Antigen Name(s)	Provenance Source
D [auth H], F [auth D], H [auth F]	Heavy Chain	IGHV3	-	factor h-binding protein	SAbDab (2024-12-06)
E [auth L], G [auth E], I [auth G]	Light Chain	IGKV3	Kappa	factor h-binding protein	SAbDab (2024-12-06)

Chains	Accession	Name	Description	Comments	Source
A, B, C	PF08794	Factor H binding protein, C-terminal (FHBP_C)	Factor H binding protein, C-terminal	Factor H binding protein (also known as GNA1870) is a surface exposed lipoprotein in Neisseria meningitidis that is a potent antigen and a potential candidate for a vaccine against meningococcal disease [1-4]. The structure of the C-terminal domain c ...	Factor H binding protein (also known as GNA1870) is a surface exposed lipoprotein in Neisseria meningitidis that is a potent antigen and a potential candidate for a vaccine against meningococcal disease [1-4]. The structure of the C-terminal domain consists of an anti-parallel beta barrel overlaid by a short alpha helical region [1,5]. This domain is highly similar to Transferrin-binding protein B beta barrel (Pfam:PF01298).	Domain

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
D [auth H], F [auth D], H [auth F]	Fab Heavy chain	-	-	-
A, B, C	Factor H-binding protein	-	-	cell periphery cell outer membrane cellular anatomical structure external encapsulating structure membrane cell envelope outer membrane
E [auth L], G [auth E], I [auth G]	Fab light Chains	-	-	-

Chains	Accession	Name	Type
A, B, C	IPR011250	Outer membrane protein/outer membrane enzyme PagP, beta-barrel	Homologous Superfamily
A, B, C	IPR014902	Factor H binding protein-like, C-terminal	Domain
A, B, C	IPR049377	Factor H binding protein, N-terminal	Domain
A, B, C	IPR049378	Factor H binding protein	Family