Annotations: 8D5Q

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
C	SCOP2B Superfamily	MHC antigen-recognition domain	8034809	3000521	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	DUF1968	e8d5qA2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: DUF1968	ECOD (1.6)
A	V-set_4	e8d5qA1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: V-set_4	ECOD (1.6)
B	C1-set	e8d5qB2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: C1-set	ECOD (1.6)
B	V-set_3	e8d5qB1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: V-set_3	ECOD (1.6)
C	MHC_I	e8d5qC1	A: a+b two layers	X: MHC antigen-recognition domain (From Topology)	H: MHC antigen-recognition domain (From Topology)	T: MHC antigen-recognition domain	F: MHC_I	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
C	PF00129	Class I Histocompatibility antigen, domains alpha 1 and 2 (MHC_I)	Class I Histocompatibility antigen, domains alpha 1 and 2	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	TCR-alpha	-	-	-
B	TCR-beta	-	-	-
C	H-2 class I histocompatibility antigen, L-D alpha chain	-	response to stimulus immune response immune system process antigen processing and presentation antigen processing and presentation of peptide antigen via MHC class I antigen processing and presentation of peptide antigen defense response response to stress	membrane-bounded organelle intracellular anatomical structure organelle subcompartment membrane lumenal side of endoplasmic reticulum membrane intracellular membrane-bounded organelle endomembrane system side of membrane lumenal side of membrane endoplasmic reticulum subcompartment intracellular organelle cellular anatomical structure organelle nuclear outer membrane-endoplasmic reticulum membrane network membrane-bounded organelle intracellular anatomical structure organelle subcompartment membrane lumenal side of endoplasmic reticulum membrane intracellular membrane-bounded organelle endomembrane system side of membrane lumenal side of membrane endoplasmic reticulum subcompartment intracellular organelle cellular anatomical structure organelle nuclear outer membrane-endoplasmic reticulum membrane network endoplasmic reticulum cytoplasm organelle membrane endoplasmic reticulum membrane intracellular vesicle phagocytic vesicle phagocytic vesicle membrane cytoplasmic vesicle membrane bounding membrane of organelle cytoplasmic vesicle vesicle membrane endocytic vesicle membrane vesicle endocytic vesicle MHC class I protein complex MHC protein complex cell periphery protein-containing complex plasma membrane protein complex plasma membrane membrane protein complex
D [auth E]	Dense granule protein 6, HF10 peptide	-	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
C	IPR036179	Immunoglobulin-like domain superfamily	Homologous Superfamily
C	IPR050208	Antigen-presenting and immune regulatory MHC class I-related	Family
C	IPR037055	MHC class I-like antigen recognition-like superfamily	Homologous Superfamily
C	IPR003597	Immunoglobulin C1-set	Domain
C	IPR010579	MHC class I, alpha chain, C-terminal	Domain
C	IPR013783	Immunoglobulin-like fold	Homologous Superfamily
C	IPR011161	MHC class I-like antigen recognition-like	Domain
C	IPR011162	MHC classes I/II-like antigen recognition protein	Homologous Superfamily
C	IPR007110	Immunoglobulin-like domain	Domain
C	IPR001039	MHC class I alpha chain, alpha1 alpha2 domains	Domain
C	IPR003006	Immunoglobulin/major histocompatibility complex, conserved site	Conserved Site

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.