8WV1 | pdb_00008wv1

Ambient Temperature Structure of 50S Ribosomal Subunit from Thermus Thermophilus

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
HA [auth c]	SCOP2B Superfamily	Translation proteins SH3-like KOW motif containing domain	8033194	3000334	SCOP2B (2022-06-29)
HA [auth c]	SCOP2B Superfamily	Nucleic acid-binding proteins	8033195	3000135	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Translation proteins SH3-like KOW motif containing domain	8033194	3000334	SCOP2B (2022-06-29)
C	SCOP2B Superfamily	Nucleic acid-binding proteins	8033195	3000135	SCOP2B (2022-06-29)
IA [auth d]	SCOP2B Superfamily	Translational proteins	8033197	3000811	SCOP2B (2022-06-29)
D	SCOP2B Superfamily	Translational proteins	8033197	3000811	SCOP2B (2022-06-29)
JA [auth e]	SCOP2B Superfamily	Ribosomal protein L4	8033198	3001146	SCOP2B (2022-06-29)
E	SCOP2B Superfamily	Ribosomal protein L4	8033198	3001146	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Ribosomal protein L6	8033203	3000724	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Ribosomal protein L6	8033202	3000724	SCOP2B (2022-06-29)
LA [auth g]	SCOP2B Superfamily	Ribosomal protein L6	8033203	3000724	SCOP2B (2022-06-29)
LA [auth g]	SCOP2B Superfamily	Ribosomal protein L6	8033202	3000724	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	L9 N-domain-like	8042935	3000338	SCOP2B (2022-06-29)
MA [auth h]	SCOP2B Superfamily	L9 N-domain-like	8042935	3000338	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	Ribosomal protein L13	8033205	3001134	SCOP2B (2022-06-29)
NA [auth i]	SCOP2B Superfamily	Ribosomal protein L13	8033205	3001134	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	50S Ribosomal protein L14-like	8042936	3000433	SCOP2B (2022-06-29)
OA [auth j]	SCOP2B Superfamily	50S Ribosomal protein L14-like	8042936	3000433	SCOP2B (2022-06-29)
K	SCOP2B Superfamily	Ribosomal proteins L15p and L18e	8033207	3001045	SCOP2B (2022-06-29)
PA [auth k]	SCOP2B Superfamily	Ribosomal proteins L15p and L18e	8033207	3001045	SCOP2B (2022-06-29)
L	SCOP2B Superfamily	Ribosomal protein L16p/L10e	8043627	3000884	SCOP2B (2022-06-29)
QA [auth l]	SCOP2B Superfamily	Ribosomal protein L16p/L10e	8043627	3000884	SCOP2B (2022-06-29)
M	SCOP2B Superfamily	Prokaryotic ribosomal protein L17	8032744	3000995	SCOP2B (2022-06-29)
RA [auth m]	SCOP2B Superfamily	Prokaryotic ribosomal protein L17	8032744	3000995	SCOP2B (2022-06-29)
N	SCOP2B Superfamily	Translational machinery components	8033211	3000571	SCOP2B (2022-06-29)
SA [auth n]	SCOP2B Superfamily	Translational machinery components	8033211	3000571	SCOP2B (2022-06-29)
O	SCOP2B Superfamily	Translation proteins SH3-like KOW motif containing domain	8033214	3000334	SCOP2B (2022-06-29)
TA [auth o]	SCOP2B Superfamily	Translation proteins SH3-like KOW motif containing domain	8033214	3000334	SCOP2B (2022-06-29)
UA [auth p]	SCOP2B Superfamily	Ribosomal protein L20	8033216	3000563	SCOP2B (2022-06-29)
P	SCOP2B Superfamily	Ribosomal protein L20	8033216	3000563	SCOP2B (2022-06-29)
Q	SCOP2B Superfamily	l21p-like	8033218	3002005	SCOP2B (2022-06-29)
VA [auth q]	SCOP2B Superfamily	l21p-like	8033218	3002005	SCOP2B (2022-06-29)
R	SCOP2B Superfamily	Ribosomal protein L22	8033220	3001078	SCOP2B (2022-06-29)
WA [auth r]	SCOP2B Superfamily	Ribosomal protein L22	8033220	3001078	SCOP2B (2022-06-29)
XA [auth s]	SCOP2B Superfamily	Ribosomal proteins S24e, L23 and L15e	8033219	3000210	SCOP2B (2022-06-29)
S	SCOP2B Superfamily	Ribosomal proteins S24e, L23 and L15e	8033219	3000210	SCOP2B (2022-06-29)
T	SCOP2B Superfamily	Translation proteins SH3-like KOW motif containing domain	8033223	3000334	SCOP2B (2022-06-29)
YA [auth t]	SCOP2B Superfamily	Translation proteins SH3-like KOW motif containing domain	8033223	3000334	SCOP2B (2022-06-29)
AB [auth v]	SCOP2B Superfamily	Ribosomal L27 protein-like	8041210	3000539	SCOP2B (2022-06-29)
V	SCOP2B Superfamily	Ribosomal L27 protein-like	8041210	3000539	SCOP2B (2022-06-29)
BB [auth w]	SCOP2B Superfamily	L28p-like	8042932	3001966	SCOP2B (2022-06-29)
W	SCOP2B Superfamily	L28p-like	8042932	3001966	SCOP2B (2022-06-29)
X	SCOP2B Superfamily	Ribosomal protein L29 (L29p)	8042933	3000713	SCOP2B (2022-06-29)
CB [auth x]	SCOP2B Superfamily	Ribosomal protein L29 (L29p)	8042933	3000713	SCOP2B (2022-06-29)
Z	SCOP2B Superfamily	L28p-like	8033189	3001966	SCOP2B (2022-06-29)
EB [auth z]	SCOP2B Superfamily	L28p-like	8033189	3001966	SCOP2B (2022-06-29)
FB [auth 5]	SCOP2B Superfamily	Zn-binding ribosomal proteins	8033190	3001320	SCOP2B (2022-06-29)
AA [auth 0]	SCOP2B Superfamily	Zn-binding ribosomal proteins	8033190	3001320	SCOP2B (2022-06-29)
GB [auth 6]	SCOP2B Superfamily	Zn-binding ribosomal proteins	8033191	3001320	SCOP2B (2022-06-29)
BA [auth 13]	SCOP2B Superfamily	Zn-binding ribosomal proteins	8033191	3001320	SCOP2B (2022-06-29)
DA [auth 3]	SCOP2B Superfamily	L35p-like	8033192	3000790	SCOP2B (2022-06-29)
IB [auth 8]	SCOP2B Superfamily	L35p-like	8033192	3000790	SCOP2B (2022-06-29)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
C, HA [auth c]	PF03947	Ribosomal Proteins L2, C-terminal domain (Ribosomal_L2_C)	Ribosomal Proteins L2, C-terminal domain		Domain
C, HA [auth c]	PF00181	Ribosomal Proteins L2, RNA binding domain (Ribosomal_L2)	Ribosomal Proteins L2, RNA binding domain		Domain
D, IA [auth d]	PF00297	Ribosomal protein L3 (Ribosomal_L3)	Ribosomal protein L3	-	Family
E, JA [auth e]	PF00573	Ribosomal protein L4/L1 family (Ribosomal_L4)	Ribosomal protein L4/L1 family	-	Family
F, KA [auth f]	PF00281	Ribosomal protein L5 (Ribosomal_L5)	Ribosomal protein L5		Domain
F, KA [auth f]	PF00673	ribosomal L5P family C-terminus (Ribosomal_L5_C)	ribosomal L5P family C-terminus	This region is found associated with Pfam:PF00281.	Domain
G, LA [auth g]	PF00347	Ribosomal protein L6 (Ribosomal_L6)	Ribosomal protein L6		Domain
H, MA [auth h]	PF01281	Ribosomal protein L9, N-terminal domain (Ribosomal_L9_N)	Ribosomal protein L9, N-terminal domain		Domain
H, MA [auth h]	PF03948	Ribosomal protein L9, C-terminal domain (Ribosomal_L9_C)	Ribosomal protein L9, C-terminal domain		Domain
I, NA [auth i]	PF00572	Ribosomal protein L13 (Ribosomal_L13)	Ribosomal protein L13	-	Family
J, OA [auth j]	PF00238	Ribosomal protein L14p/L23e (Ribosomal_L14)	Ribosomal protein L14p/L23e		Domain
K, PA [auth k]	PF00828	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A (Ribosomal_L27A)	Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A	This family includes higher eukaryotic ribosomal 60S L27A, archaeal 50S L18e, prokaryotic 50S L15, fungal mitochondrial L10, plant L27A, mitochondrial L15 and chloroplast L18-3 proteins.	Domain
L, QA [auth l]	PF00252	Ribosomal protein L16p/L10e (Ribosomal_L16)	Ribosomal protein L16p/L10e		Domain
M, RA [auth m]	PF01196	Ribosomal protein L17 (Ribosomal_L17)	Ribosomal protein L17	-	Family
O, TA [auth o]	PF01245	Ribosomal protein L19 (Ribosomal_L19)	Ribosomal protein L19	-	Family
P, UA [auth p]	PF00453	Ribosomal protein L20 (Ribosomal_L20)	Ribosomal protein L20	-	Family
Q, VA [auth q]	PF00829	Ribosomal prokaryotic L21 protein (Ribosomal_L21p)	Ribosomal prokaryotic L21 protein	-	Family
R, WA [auth r]	PF00237	Ribosomal protein L22p/L17e (Ribosomal_L22)	Ribosomal protein L22p/L17e	This family includes L22 from prokaryotes and chloroplasts and L17 from eukaryotes.	Domain
S, XA [auth s]	PF00276	Ribosomal protein L23 (Ribosomal_L23)	Ribosomal protein L23	-	Family
T, YA [auth t]	PF17136	Ribosomal proteins 50S L24/mitochondrial 39S L24 (ribosomal_L24)	Ribosomal proteins 50S L24/mitochondrial 39S L24	-	Family
T, YA [auth t]	PF00467	KOW motif (KOW)	KOW motif	-	Family
U, ZA [auth u]	PF14693	Ribosomal protein TL5, C-terminal domain (Ribosomal_TL5_C)	Ribosomal protein TL5, C-terminal domain	This family contains the C-terminal domain of ribosomal protein TL5. The N-terminal domain, which binds to 5S rRNA, is contained in family Ribosomal_L25p, Pfam:PF01386. Full length (N- and C-terminal domain) homologues of TL5 are also known as CTC pr ...	This family contains the C-terminal domain of ribosomal protein TL5. The N-terminal domain, which binds to 5S rRNA, is contained in family Ribosomal_L25p, Pfam:PF01386. Full length (N- and C-terminal domain) homologues of TL5 are also known as CTC proteins. TL5 or CTC are not found in Eukarya or Archaea. In some Bacteria, including E. coli, this ribosomal subunit occurs as a single domain protein (named Ribosomal subunit L25), where the only domain is homologous to TL5 N-terminal domain (hence included in family Pfam:PF01386). The function of the C-terminal domain of TLC is at present unknown.	Domain
U, ZA [auth u]	PF01386	Ribosomal L25p family (Ribosomal_L25p)	Ribosomal L25p family	Ribosomal protein L25 is an RNA binding protein, that binds 5S rRNA. This family includes Ctc from B. subtilis Swiss:P14194, which is induced by stress.	Domain
AB [auth v], V	PF01016	Ribosomal L27 protein (Ribosomal_L27)	Ribosomal L27 protein	-	Family
BB [auth w], W	PF00830	Ribosomal L28 family (Ribosomal_L28)	Ribosomal L28 family	-	Family
CB [auth x], X	PF00831	Ribosomal L29 protein (Ribosomal_L29)	Ribosomal L29 protein	-	Family
DB [auth y], Y	PF00327	Ribosomal protein L30p/L7e (Ribosomal_L30)	Ribosomal protein L30p/L7e	This family includes prokaryotic L30 and eukaryotic L7.	Domain
EB [auth z], Z	PF01197	Ribosomal protein L31 (Ribosomal_L31)	Ribosomal protein L31	-	Family
AA [auth 0], FB [auth 5]	PF01783	Ribosomal L32p protein family (Ribosomal_L32p)	Ribosomal L32p protein family	-	Family
BA [auth 13], GB [auth 6]	PF00471	Ribosomal protein L33 (Ribosomal_L33)	Ribosomal protein L33	-	Family
CA [auth 2], HB [auth 7]	PF00468	Ribosomal protein L34 (Ribosomal_L34)	Ribosomal protein L34	-	Family
DA [auth 3], IB [auth 8]	PF01632	Ribosomal protein L35 (Ribosomal_L35p)	Ribosomal protein L35	-	Family
EA [auth 4], JB [auth 9]	PF00444	Ribosomal protein L36 (Ribosomal_L36)	Ribosomal protein L36		Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, FA [auth a]	23S rRNA	-	-	-
B, GA [auth b]	5S rRNA	-	-	-
C, HA [auth c]	50S ribosomal protein L2	RNA binding binding rRNA binding nucleic acid binding structural molecule activity structural constituent of ribosome transferase activity catalytic activity	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle ribosomal subunit intracellular organelle cellular anatomical structure ribonucleoprotein complex organelle membraneless organelle ribosome large ribosomal subunit
D, IA [auth d]	50S ribosomal protein L3	structural molecule activity structural constituent of ribosome RNA binding binding rRNA binding nucleic acid binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
E, JA [auth e]	50S ribosomal protein L4	structural molecule activity structural constituent of ribosome RNA binding binding rRNA binding nucleic acid binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex ribonucleoprotein complex intracellular organelle cellular anatomical structure intracellular anatomical structure organelle membraneless organelle intracellular membraneless organelle ribosome
F, KA [auth f]	50S ribosomal protein L5	RNA binding binding tRNA binding nucleic acid binding structural molecule activity structural constituent of ribosome rRNA binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex ribonucleoprotein complex intracellular organelle cellular anatomical structure intracellular anatomical structure organelle membraneless organelle intracellular membraneless organelle ribosome
G, LA [auth g]	50S ribosomal protein L6	structural molecule activity structural constituent of ribosome RNA binding binding rRNA binding nucleic acid binding	biosynthetic process cytoplasmic translation metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
H, MA [auth h]	Large ribosomal subunit protein bL9	structural molecule activity structural constituent of ribosome RNA binding binding rRNA binding nucleic acid binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex ribonucleoprotein complex intracellular organelle cellular anatomical structure intracellular anatomical structure organelle membraneless organelle intracellular membraneless organelle ribosome
I, NA [auth i]	50S ribosomal protein L13	RNA binding binding nucleic acid binding mRNA binding structural molecule activity structural constituent of ribosome	regulation of cellular process negative regulation of biological process regulation of primary metabolic process post-transcriptional regulation of gene expression negative regulation of translation negative regulation of cellular process protein metabolic process negative regulation of protein metabolic process negative regulation of macromolecule metabolic process regulation of biosynthetic process regulation of biological process regulation of protein metabolic process negative regulation of metabolic process biological regulation regulation of cellular process negative regulation of biological process regulation of primary metabolic process post-transcriptional regulation of gene expression negative regulation of translation negative regulation of cellular process protein metabolic process negative regulation of protein metabolic process negative regulation of macromolecule metabolic process regulation of biosynthetic process regulation of biological process regulation of protein metabolic process negative regulation of metabolic process biological regulation primary metabolic process regulation of macromolecule metabolic process gene expression translation macromolecule biosynthetic process regulation of gene expression negative regulation of gene expression biosynthetic process negative regulation of biosynthetic process regulation of translation negative regulation of macromolecule biosynthetic process regulation of macromolecule biosynthetic process metabolic process cellular process macromolecule metabolic process regulation of metabolic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
J, OA [auth j]	Large ribosomal subunit protein uL14	structural molecule activity structural constituent of ribosome RNA binding binding rRNA binding nucleic acid binding large ribosomal subunit rRNA binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
K, PA [auth k]	50S ribosomal protein L15	structural molecule activity structural constituent of ribosome RNA binding binding rRNA binding nucleic acid binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
L, QA [auth l]	50S ribosomal protein L16	RNA binding binding tRNA binding nucleic acid binding structural molecule activity structural constituent of ribosome rRNA binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
M, RA [auth m]	50S ribosomal protein L17	structural molecule activity structural constituent of ribosome	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
N, SA [auth n]	50S ribosomal protein L18	RNA binding binding rRNA binding 5S rRNA binding nucleic acid binding structural molecule activity structural constituent of ribosome	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
O, TA [auth o]	50S ribosomal protein L19	structural molecule activity structural constituent of ribosome RNA binding binding rRNA binding nucleic acid binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
P, UA [auth p]	50S ribosomal protein L20	structural molecule activity structural constituent of ribosome RNA binding binding rRNA binding nucleic acid binding	ribonucleoprotein complex biogenesis organelle assembly protein-containing complex organization membraneless organelle assembly ribosomal large subunit biogenesis protein-RNA complex assembly cellular component biogenesis cellular component organization ribosome biogenesis organelle organization protein-RNA complex organization cellular component assembly ribosomal large subunit assembly protein-containing complex assembly ribonucleoprotein complex biogenesis organelle assembly protein-containing complex organization membraneless organelle assembly ribosomal large subunit biogenesis protein-RNA complex assembly cellular component biogenesis cellular component organization ribosome biogenesis organelle organization protein-RNA complex organization cellular component assembly ribosomal large subunit assembly protein-containing complex assembly cellular process cellular component organization or biogenesis ribosome assembly biosynthetic process metabolic process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex ribonucleoprotein complex intracellular organelle cellular anatomical structure intracellular anatomical structure organelle membraneless organelle intracellular membraneless organelle ribosome
Q, VA [auth q]	50S ribosomal protein L21	structural molecule activity structural constituent of ribosome RNA binding binding rRNA binding nucleic acid binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex ribonucleoprotein complex cellular anatomical structure intracellular anatomical structure cytoplasm intracellular organelle organelle membraneless organelle intracellular membraneless organelle ribosome
R, WA [auth r]	50S ribosomal protein L22	structural molecule activity structural constituent of ribosome RNA binding binding rRNA binding nucleic acid binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
S, XA [auth s]	50S ribosomal protein L23	structural molecule activity structural constituent of ribosome RNA binding binding rRNA binding nucleic acid binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex ribonucleoprotein complex intracellular organelle cellular anatomical structure intracellular anatomical structure organelle membraneless organelle intracellular membraneless organelle ribosome
T, YA [auth t]	Large ribosomal subunit protein uL24	structural molecule activity structural constituent of ribosome RNA binding binding rRNA binding nucleic acid binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex ribonucleoprotein complex intracellular organelle cellular anatomical structure intracellular anatomical structure organelle membraneless organelle intracellular membraneless organelle ribosome
U, ZA [auth u]	50S ribosomal protein L25	RNA binding binding rRNA binding 5S rRNA binding nucleic acid binding structural molecule activity structural constituent of ribosome	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
AB [auth v], V	Large ribosomal subunit protein bL27	structural molecule activity structural constituent of ribosome	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
BB [auth w], W	Large ribosomal subunit protein bL28	structural molecule activity structural constituent of ribosome	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex ribonucleoprotein complex intracellular organelle cellular anatomical structure intracellular anatomical structure organelle membraneless organelle intracellular membraneless organelle ribosome
CB [auth x], X	Large ribosomal subunit protein uL29	structural molecule activity structural constituent of ribosome	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
DB [auth y], Y	50S ribosomal protein L30	structural molecule activity structural constituent of ribosome	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
EB [auth z], Z	50S ribosomal protein L31	structural molecule activity structural constituent of ribosome cation binding ion binding binding metal ion binding small molecule binding RNA binding rRNA binding nucleic acid binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex ribonucleoprotein complex intracellular organelle cellular anatomical structure intracellular anatomical structure organelle membraneless organelle intracellular membraneless organelle ribosome
AA [auth 0], FB [auth 5]	50S ribosomal protein L32	structural molecule activity structural constituent of ribosome	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle ribosomal subunit intracellular organelle cellular anatomical structure ribonucleoprotein complex organelle membraneless organelle ribosome large ribosomal subunit
BA [auth 13], GB [auth 6]	50S ribosomal protein L33	RNA binding binding tRNA binding nucleic acid binding structural molecule activity structural constituent of ribosome rRNA binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex ribonucleoprotein complex cellular anatomical structure intracellular anatomical structure cytoplasm intracellular organelle organelle membraneless organelle intracellular membraneless organelle ribosome
CA [auth 2], HB [auth 7]	50S ribosomal protein L34	structural molecule activity structural constituent of ribosome	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex ribonucleoprotein complex intracellular organelle cellular anatomical structure intracellular anatomical structure organelle membraneless organelle intracellular membraneless organelle ribosome
DA [auth 3], IB [auth 8]	50S ribosomal protein L35	structural molecule activity structural constituent of ribosome	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol protein-containing complex intracellular anatomical structure intracellular membraneless organelle intracellular organelle ribosomal subunit cytosolic large ribosomal subunit cellular anatomical structure cytosolic ribosome organelle ribonucleoprotein complex membraneless organelle ribosome cytoplasm cytosol large ribosomal subunit
EA [auth 4], JB [auth 9]	50S ribosomal protein L36	structural molecule activity structural constituent of ribosome cation binding ion binding binding metal ion binding small molecule binding	biosynthetic process metabolic process cellular process primary metabolic process protein metabolic process macromolecule metabolic process translation gene expression macromolecule biosynthetic process	protein-containing complex ribonucleoprotein complex cellular anatomical structure intracellular anatomical structure cytoplasm intracellular organelle organelle membraneless organelle intracellular membraneless organelle ribosome

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
C, HA [auth c]	IPR022669	Large ribosomal subunit protein uL2, C-terminal	Domain
C, HA [auth c]	IPR014722	Large ribosomal subunit protein uL2, domain 2	Homologous Superfamily
C, HA [auth c]	IPR008991	Translation protein SH3-like domain superfamily	Homologous Superfamily
C, HA [auth c]	IPR022671	Large ribosomal subunit protein uL2, conserved site	Conserved Site
C, HA [auth c]	IPR005880	Large ribosomal subunit protein uL2, bacterial/organellar-type	Family
C, HA [auth c]	IPR012340	Nucleic acid-binding, OB-fold	Homologous Superfamily
C, HA [auth c]	IPR022666	Large ribosomal subunit protein uL2, RNA-binding domain	Domain
C, HA [auth c]	IPR014726	Large ribosomal subunit protein uL2, domain 3	Homologous Superfamily
C, HA [auth c]	IPR002171	Large ribosomal subunit protein uL2	Family
D, IA [auth d]	IPR019926	Large ribosomal subunit protein uL3, conserved site	Conserved Site
D, IA [auth d]	IPR019927	Large ribosomal subunit protein uL3, bacterial/organelle-type	Family
D, IA [auth d]	IPR009000	Translation protein, beta-barrel domain superfamily	Homologous Superfamily
D, IA [auth d]	IPR000597	Large ribosomal subunit protein uL3	Family
E, JA [auth e]	IPR013005	Large ribosomal subunit protein uL4-like	Family
E, JA [auth e]	IPR002136	Large ribosomal subunit protein uL4	Family
E, JA [auth e]	IPR023574	Large ribosomal subunit protein uL4 domain superfamily	Homologous Superfamily
F, KA [auth f]	IPR020929	Large ribosomal subunit protein uL5, conserved site	Conserved Site
F, KA [auth f]	IPR022803	Large ribosomal subunit protein uL5 domain superfamily	Homologous Superfamily
F, KA [auth f]	IPR031309	Large ribosomal subunit protein uL5, C-terminal	Domain
F, KA [auth f]	IPR031310	Large ribosomal subunit protein uL5, N-terminal	Domain
F, KA [auth f]	IPR020930	Large ribosomal subunit protein uL5, bacterial-type	Family
F, KA [auth f]	IPR002132	Large ribosomal subunit protein uL5	Family
G, LA [auth g]	IPR020040	Large ribosomal subunit protein uL6, alpha-beta domain	Domain
G, LA [auth g]	IPR036789	Large ribosomal subunit protein uL6-like, alpha-beta domain superfamily	Homologous Superfamily
G, LA [auth g]	IPR000702	Large ribosomal subunit protein uL6-like	Family
G, LA [auth g]	IPR019906	Large ribosomal subunit protein uL6, bacterial-type	Family
H, MA [auth h]	IPR009027	Large ribosomal subunit protein bL9/RNase H1, N-terminal	Homologous Superfamily
H, MA [auth h]	IPR020594	Large ribosomal subunit protein bL9, bacteria/chloroplast	Family
H, MA [auth h]	IPR036935	Large ribosomal subunit protein bL9, N-terminal domain superfamily	Homologous Superfamily
H, MA [auth h]	IPR036791	Large ribosomal subunit protein bL9, C-terminal domain superfamily	Homologous Superfamily
H, MA [auth h]	IPR020069	Large ribosomal subunit protein bL9, C-terminal	Domain
H, MA [auth h]	IPR020070	Large ribosomal subunit protein bL9, N-terminal	Domain
H, MA [auth h]	IPR000244	Large ribosomal subunit protein bL9	Family
I, NA [auth i]	IPR023563	Large ribosomal subunit protein uL13, conserved site	Conserved Site
I, NA [auth i]	IPR005822	Large ribosomal subunit protein uL13	Family
I, NA [auth i]	IPR036899	Large ribosomal subunit protein uL13 superfamily	Homologous Superfamily
I, NA [auth i]	IPR005823	Large ribosomal subunit protein uL13, bacterial-type	Family
J, OA [auth j]	IPR005745	Large ribosomal subunit protein uL14, bacterial-type	Family
J, OA [auth j]	IPR036853	Large ribosomal subunit protein uL14 superfamily	Homologous Superfamily
J, OA [auth j]	IPR000218	Large ribosomal subunit protein uL14	Family
J, OA [auth j]	IPR019972	Large ribosomal subunit protein uL14, conserved site	Conserved Site
K, PA [auth k]	IPR005749	Large ribosomal subunit protein uL15, bacterial-type	Family
K, PA [auth k]	IPR021131	Large ribosomal subunit protein uL15/eL18	Domain
K, PA [auth k]	IPR030878	Large ribosomal subunit protein uL15	Family
K, PA [auth k]	IPR001196	Large ribosomal subunit protein uL15, conserved site	Conserved Site
K, PA [auth k]	IPR036227	Large ribosomal subunit protein uL15/eL18 superfamily	Homologous Superfamily
L, QA [auth l]	IPR036920	Large ribosomal subunit protein uL16 superfamily	Homologous Superfamily
L, QA [auth l]	IPR000114	Large ribosomal subunit protein uL16, bacterial-type	Family
L, QA [auth l]	IPR016180	Large ribosomal subunit protein uL16 domain	Domain
L, QA [auth l]	IPR047873	Large ribosomal subunit protein uL16	Family
M, RA [auth m]	IPR036373	Large ribosomal subunit protein bL17 superfamily	Homologous Superfamily
M, RA [auth m]	IPR000456	Large ribosomal subunit protein bL17	Family
N, SA [auth n]	IPR005484	Large ribosomal subunit protein uL18	Family
N, SA [auth n]	IPR004389	Large ribosomal subunit protein uL18, bacterial-type	Family
O, TA [auth o]	IPR001857	Large ribosomal subunit protein bL19	Family
O, TA [auth o]	IPR038657	Large ribosomal subunit protein bL19 superfamily	Homologous Superfamily
O, TA [auth o]	IPR018257	Large ribosomal subunit protein bL19, conserved site	Conserved Site
O, TA [auth o]	IPR008991	Translation protein SH3-like domain superfamily	Homologous Superfamily
P, UA [auth p]	IPR049946	Large ribosomal subunit protein bL20, conserved site	Conserved Site
P, UA [auth p]	IPR035566	Ribosomal protein bL20, C-terminal	Homologous Superfamily
P, UA [auth p]	IPR005813	Large ribosomal subunit protein bL20	Family
Q, VA [auth q]	IPR028909	Large ribosomal subunit protein bL21-like	Family
Q, VA [auth q]	IPR001787	Large ribosomal subunit protein bL21	Family
Q, VA [auth q]	IPR036164	Large ribosomal subunit protein bL21-like superfamily	Homologous Superfamily
R, WA [auth r]	IPR047867	Large ribosomal subunit protein uL22, bacterial/organelle-type	Family
R, WA [auth r]	IPR018260	Large ribosomal subunit protein uL22, conserved site	Conserved Site
R, WA [auth r]	IPR036394	Ribosomal protein uL22 superfamily	Homologous Superfamily
R, WA [auth r]	IPR001063	Large ribosomal subunit protein uL22	Family
R, WA [auth r]	IPR005727	Large ribosomal subunit protein uL22, bacterial/chloroplast-type	Family
S, XA [auth s]	IPR012678	Ribosomal protein uL23/eL15/eS24 core domain superfamily	Homologous Superfamily
S, XA [auth s]	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily	Homologous Superfamily
S, XA [auth s]	IPR013025	Large ribosomal subunit protein uL23-like	Family
T, YA [auth t]	IPR003256	Large ribosomal subunit protein uL24	Family
T, YA [auth t]	IPR041988	Large ribosomal subunit protein uL24, KOW domain	Domain
T, YA [auth t]	IPR014722	Large ribosomal subunit protein uL2, domain 2	Homologous Superfamily
T, YA [auth t]	IPR005824	KOW	Domain
T, YA [auth t]	IPR008991	Translation protein SH3-like domain superfamily	Homologous Superfamily
T, YA [auth t]	IPR005825	Large ribosomal subunit protein uL24, conserved site	Conserved Site
U, ZA [auth u]	IPR011035	Large ribosomal subunit protein bL25/Gln-tRNA synthetase, anti-codon-binding domain superfamily	Homologous Superfamily
U, ZA [auth u]	IPR001021	Ribosomal protein bL25, long-form	Family
U, ZA [auth u]	IPR029751	Large ribosomal subunit protein bL25, L25 domain	Domain
U, ZA [auth u]	IPR037121	Large ribosomal subunit protein bL25, C-terminal	Homologous Superfamily
U, ZA [auth u]	IPR020057	Large ribosomal subunit protein bL25, beta domain	Domain
U, ZA [auth u]	IPR020056	Large ribosomal subunit protein bL25/Gln-tRNA synthetase, N-terminal	Homologous Superfamily
U, ZA [auth u]	IPR050070	Bacterial ribosomal protein bL25	Family
AB [auth v], V	IPR001684	Large ribosomal subunit protein bL27	Family
AB [auth v], V	IPR018261	Large ribosomal subunit protein bL27, conserved site	Conserved Site
BB [auth w], W	IPR001383	Large ribosomal subunit protein bL28, bacterial-type	Family
BB [auth w], W	IPR050096	Bacterial ribosomal protein bL28	Family
BB [auth w], W	IPR026569	Large ribosomal subunit protein bL28	Family
BB [auth w], W	IPR034704	Large ribosomal subunit protein bL28/bL31-like superfamily	Homologous Superfamily
CB [auth x], X	IPR050063	Universal ribosomal protein uL29	Family
CB [auth x], X	IPR001854	Large ribosomal subunit protein uL29	Family
CB [auth x], X	IPR036049	Large ribosomal subunit protein uL29 superfamily	Homologous Superfamily
CB [auth x], X	IPR018254	Large ribosomal subunit protein uL29, conserved site	Conserved Site
DB [auth y], Y	IPR036919	Large ribosomal subunit protein uL30, ferredoxin-like fold domain superfamily	Homologous Superfamily
DB [auth y], Y	IPR005996	Large ribosomal subunit protein uL30, bacterial-type	Family
DB [auth y], Y	IPR016082	Large ribosomal subunit protein uL30-like, ferredoxin-like fold domain	Domain
DB [auth y], Y	IPR018038	Large ribosomal subunit protein uL30, conserved site	Conserved Site
EB [auth z], Z	IPR002150	Large ribosomal subunit protein bL31 type A/B	Family
EB [auth z], Z	IPR027491	Large ribosomal subunit protein bL31 type A	Family
EB [auth z], Z	IPR042105	Large ribosomal subunit protein bL31 superfamily	Homologous Superfamily
EB [auth z], Z	IPR034704	Large ribosomal subunit protein bL28/bL31-like superfamily	Homologous Superfamily
AA [auth 0], FB [auth 5]	IPR002677	Large ribosomal subunit protein bL32	Family
AA [auth 0], FB [auth 5]	IPR011332	Zinc-binding ribosomal protein	Homologous Superfamily
AA [auth 0], FB [auth 5]	IPR044957	Large ribosomal subunit protein bL32, bacterial type	Family
BA [auth 13], GB [auth 6]	IPR011332	Zinc-binding ribosomal protein	Homologous Superfamily
BA [auth 13], GB [auth 6]	IPR038584	Large ribosomal subunit protein bL33 superfamily	Homologous Superfamily
BA [auth 13], GB [auth 6]	IPR001705	Large ribosomal subunit protein bL33	Family
BA [auth 13], GB [auth 6]	IPR018264	Large ribosomal subunit protein bL33, conserved site	Conserved Site
CA [auth 2], HB [auth 7]	IPR020939	Large ribosomal subunit protein bL34, conserved site	Conserved Site
CA [auth 2], HB [auth 7]	IPR000271	Large ribosomal subunit protein bL34	Family
DA [auth 3], IB [auth 8]	IPR021137	Large ribosomal subunit protein bL35-like	Family
DA [auth 3], IB [auth 8]	IPR018265	Large ribosomal subunit protein bL35, conserved site	Conserved Site
DA [auth 3], IB [auth 8]	IPR001706	Large ribosomal subunit protein bL35	Family
DA [auth 3], IB [auth 8]	IPR037229	Large ribosomal subunit protein bL35 superfamily	Homologous Superfamily
EA [auth 4], JB [auth 9]	IPR000473	Large ribosomal subunit protein bL36	Family
EA [auth 4], JB [auth 9]	IPR035977	Large ribosomal subunit protein bL36 superfamily	Homologous Superfamily