5MU

5-METHYLURIDINE 5'-MONOPHOSPHATE

Created:	1999-07-08
Last modified:	2011-06-04

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661 entries where 5MU is found in a polymer sequence

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Chemical Details
Formal Charge	0
Atom Count	37
Chiral Atom Count	4
Bond Count	38
Aromatic Bond Count	0

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Chemical Component Summary
Name	5-METHYLURIDINE 5'-MONOPHOSPHATE
Systematic Name (OpenEye OEToolkits)	[(2R,3S,4R,5R)-3,4-dihydroxy-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)oxolan-2-yl]methyl dihydrogen phosphate
Formula	C₁₀ H₁₅ N₂ O₉ P
Molecular Weight	338.208
Type	RNA LINKING

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C1NC(=O)N(C=C1C)C2OC(C(O)C2O)COP(=O)(O)O
SMILES	CACTVS	3.341	CC1=CN([CH]2O[CH](CO[P](O)(O)=O)[CH](O)[CH]2O)C(=O)NC1=O
SMILES	OpenEye OEToolkits	1.5.0	CC1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)O)O)O
Canonical SMILES	CACTVS	3.341	CC1=CN([C@@H]2O[C@H](CO[P](O)(O)=O)[C@@H](O)[C@H]2O)C(=O)NC1=O
Canonical SMILES	OpenEye OEToolkits	1.5.0	CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)O)O
InChI	InChI	1.03	InChI=1S/C10H15N2O9P/c1-4-2-12(10(16)11-8(4)15)9-7(14)6(13)5(21-9)3-20-22(17,18)19/h2,5-7,9,13-14H,3H2,1H3,(H,11,15,16)(H2,17,18,19)/t5-,6-,7-,9-/m1/s1
InChIKey	InChI	1.03	IGWHDMPTQKSDTL-JXOAFFINSA-N

Drug Info: DrugBank

DrugBank ID	DB04243
Name	TMP
Groups	experimental
Synonyms	5-methyluridine 5'-monophosphate ribosylthymidine 5'-monophosphate rTMP TMP 5-methyluridine 5'-phosphate ribo-TMP 5-methyl-5'-uridylic acid ribothymidine 5'-phosphate ribosylthymine 5'-monophosphate ribosylthymine 5'-phosphate ribosylthymidine 5'-phosphate
Categories	Deoxyribonucleotides Nucleic Acids, Nucleotides, and Nucleosides Nucleotides Pyrimidine Nucleotides Pyrimidines Thymine Nucleotides

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Single-stranded DNA-binding protein	MASRGVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDKATGEMK...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682