AZQ

AZAPROPAZONE

Created:	2005-07-25
Last modified:	2018-05-18

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3 entries where AZQ is found as a standalone ligand

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Chemical Details
Formal Charge	0
Atom Count	42
Chiral Atom Count	1
Bond Count	44
Aromatic Bond Count	6

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Chemical Component Summary
Name	AZAPROPAZONE
Systematic Name (OpenEye OEToolkits)	5-(dimethylamino)-9-methyl-2-propyl-pyrazolo[1,2-a][1,2,4]benzotriazine-1,3-dione
Formula	C₁₆ H₂₀ N₄ O₂
Molecular Weight	300.356
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	CACTVS	3.385	CCC[CH]1C(=O)N2N(C1=O)C(=Nc3ccc(C)cc23)N(C)C
SMILES	OpenEye OEToolkits	2.0.6	CCCC1C(=O)N2c3cc(ccc3N=C(N2C1=O)N(C)C)C
Canonical SMILES	CACTVS	3.385	CCC[C@H]1C(=O)N2N(C1=O)C(=Nc3ccc(C)cc23)N(C)C
Canonical SMILES	OpenEye OEToolkits	2.0.6	CCCC1C(=O)N2c3cc(ccc3N=C(N2C1=O)N(C)C)C
InChI	InChI	1.03	InChI=1S/C16H20N4O2/c1-5-6-11-14(21)19-13-9-10(2)7-8-12(13)17-16(18(3)4)20(19)15(11)22/h7-9,11H,5-6H2,1-4H3/t11-/m0/s1
InChIKey	InChI	1.03	MPHPHYZQRGLTBO-NSHDSACASA-N

Drug Info: DrugBank

DrugBank ID	DB07402
Name	Azapropazone
Groups	withdrawn
Synonyms	Azapropazone Apazone Azapropazonum 3-Dimethylamino-7-methyl-1,2-(n-propylmalonyl)-1,2-dihydro-1,2,4-benzotriazine Azapropazon Azapropazona 1,2-Dihydro-3-dimethylamino-7-methyl-1,2-(propylmalonyl)-1,2,4-benzotriazine 5-(Dimethylamino)-9-methyl-2-propyl-1H-pyrazolo(1,2-a)(1,2,4)benzotriazine-1,3(2H)-dione
Categories	Agents causing hyperkalemia Agents that produce hypertension Analgesics Analgesics, Non-Narcotic Anti-Inflammatory Agents Anti-Inflammatory Agents, Non-Steroidal Antigout Preparations Antiinflammatory and Antirheumatic Products Antiinflammatory and Antirheumatic Products, Non-Steroids Antirheumatic Agents Musculo-Skeletal System Nephrotoxic agents Peripheral Nervous System Agents Sensory System Agents Triazines Uricosuric Agents
ATC-Code	M01AX04
CAS number	13539-59-8

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Serum albumin	MKWVTFISLLFLFSSAYSRGVFRRDAHKSEVAHRFKDLGEENFKALVLIA...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682