DCZ

2'-DEOXYCYTIDINE

Created:	2001-05-30
Last modified:	2017-07-13

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14 entries where DCZ is found as a standalone ligand1 entries where DCZ is covalently linked to polymer or other heterogen groups 15 entries where DCZ is found in a polymer sequence

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Chemical Details
Formal Charge	0
Atom Count	29
Chiral Atom Count	3
Bond Count	30
Aromatic Bond Count	0

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Chemical Component Summary
Name	2'-DEOXYCYTIDINE
Systematic Name (OpenEye OEToolkits)	4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
Formula	C₉ H₁₃ N₃ O₄
Molecular Weight	227.217
Type	DNA OH 5 PRIME TERMINUS

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C1N=C(N)C=CN1C2OC(C(O)C2)CO
SMILES	CACTVS	3.341	NC1=NC(=O)N(C=C1)[CH]2C[CH](O)[CH](CO)O2
SMILES	OpenEye OEToolkits	1.5.0	C1C(C(OC1N2C=CC(=NC2=O)N)CO)O
Canonical SMILES	CACTVS	3.341	NC1=NC(=O)N(C=C1)[C@H]2C[C@H](O)[C@@H](CO)O2
Canonical SMILES	OpenEye OEToolkits	1.5.0	C1[C@@H]([C@H](O[C@H]1N2C=CC(=NC2=O)N)CO)O
InChI	InChI	1.03	InChI=1S/C9H13N3O4/c10-7-1-2-12(9(15)11-7)8-3-5(14)6(4-13)16-8/h1-2,5-6,8,13-14H,3-4H2,(H2,10,11,15)/t5-,6+,8+/m0/s1
InChIKey	InChI	1.03	CKTSBUTUHBMZGZ-SHYZEUOFSA-N

Drug Info: DrugBank

DrugBank ID	DB02594
Name	2'-Deoxycytidine
Groups	experimental investigational
Synonyms	4-amino-1-(2-deoxy-.beta.-d-erythro-pentofuranosyl)-2(1h)-pyrimidinone Deoxyribose cytidine dC 1-(2-deoxy-.beta.-d-ribofuranosyl)cytosine dCYD 2'-Deoxycytidine
CAS number	951-77-9

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Thymidine kinase 2, mitochondrial	MLLWPLRGWAARALRCFGPGSRGSPASGPGPRRVQRRAWPPDKEQEKEKK...	unknown
Class B acid phosphatase	MRKITQAISAVCLLFALNSSAVALASSPSPLNPGTNVARLAEQAPIHWVS...	unknown
Deoxycytidine kinase	MATPPKRSCPSFSASSEGTRIKKISIEGNIAAGKSTFVNILKQLCEDWEV...	unknown
Deoxycytidine kinase	MATPPKRSCPSFSASSEGTRIKKISIEGNIAAGKSTFVNILKQLCEDWEV...	unknown	substrate

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682