DMS

DIMETHYL SULFOXIDE

Created:1999-07-08
Last modified:  2024-09-27

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Chemical Details

Formal Charge0
Atom Count10
Chiral Atom Count0
Bond Count9
Aromatic Bond Count0
2D diagram of DMS
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Chemical Component Summary

NameDIMETHYL SULFOXIDE
Systematic Name (OpenEye OEToolkits)methylsulfinylmethane
FormulaC2 H6 O S
Molecular Weight78.133
TypeNON-POLYMER

Chemical Descriptors

TypeProgramVersionDescriptor
SMILESACDLabs10.04sulfinyldimethane
SMILESCACTVS3.341C[S](C)=O
SMILESOpenEye OEToolkits1.5.0CS(=O)C
Canonical SMILESCACTVS3.341 C[S](C)=O
Canonical SMILESOpenEye OEToolkits1.5.0 CS(=O)C
InChIInChI1.03 InChI=1S/C2H6OS/c1-4(2)3/h1-2H3
InChIKeyInChI1.03 IAZDPXIOMUYVGZ-UHFFFAOYSA-N

Drug Info: DrugBank

DrugBank IDDB01093 
NameDimethyl sulfoxide
Groups
  • approved
  • vet_approved
DescriptionA highly polar organic liquid, that is used widely as a chemical solvent. Because of its ability to penetrate biological membranes, it is used as a vehicle for topical application of pharmaceuticals. It is also used to protect tissue during cryopreservation. Dimethyl sulfoxide shows a range of pharmacological activity including analgesia and anti-inflammation.
Synonyms
  • Dimetil sulfóxido
  • Diméthylsulfoxyde
  • Sulfinylbis(methane)
  • Dimethyli sulfoxidum
  • Dimethylsulfoxid
Brand Names
  • Rimso-50
  • Kemsol Liquid 70%
  • Fungizyl AC
  • Dimethyl Sulfoxide Irrigation USP
IndicationFor the symptomatic relief of patients with interstitial cystitis.
Categories
  • Antioxidants
  • Compounds used in a research, industrial, or household setting
  • Cryoprotective Agents
  • Cytochrome P-450 CYP2C19 Inhibitors
  • Cytochrome P-450 CYP2C19 inhibitors (strength unknown)
ATC-Code
  • M02AX03
  • G04BX13
CAS number67-68-5

Drug Targets

NameTarget SequencePharmacological ActionActions
Interleukin-5 receptor subunit alphaMIIVAHVLLILLGATEILQADLLPDEKISLLPPVNFTIKVTGLAQVLLQW...unknowndownregulator
Mucin-16MLKPSGLPGSSSPTRSLMTGSRSTKATPEMDSGLTGATLSPKTSTGAIVV...unknowndownregulator
Myc proto-oncogene proteinMDFFRVVENQQPPATMPLNVSFTNRNYDLDYDSVQPYFYCDEEENFYQQQ...unknowndownregulator
Cytochrome P450 2C19MDPFVVLVLCLSCLLLLSIWRQSSGRGKLPPGPTPLPVIGNILQIDIKDV...unknowninhibitor
Cytochrome P450 2D6MGLEALVPLAVIVAIFLLLVDLMHRRQRWAARYPPGPLPLPGLGNLLHVD...unknowninhibitor
View More
Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682

Related Resource References

Resource NameReference
PubChem 679
ChEMBL CHEMBL504
ChEBI CHEBI:28262
CCDC/CSD AGEQAF, AGASIL, AFIXIW, AHUVUV, ADISEN, ACESOT, AKAYEQ, ABOMEM, AJEFUS, AKOJAN, ABUFUB, ADIYES, AJIFAC, ACESIN, AKEMAF, ADABUC, ABECES, AKUVEJ, AKOCEK, ACESEJ, ABULAN, AJUXOV, ABEPOQ
COD 2242302, 2018380, 4131301, 7214896