DXP

1-DEOXY-D-XYLULOSE-5-PHOSPHATE

Created:	2002-07-03
Last modified:	2011-06-04

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6 entries where DXP is found as a standalone ligand1 entries where DXP is covalently linked to polymer or other heterogen groups

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Chemical Details
Formal Charge	0
Atom Count	24
Chiral Atom Count	2
Bond Count	23
Aromatic Bond Count	0

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Chemical Component Summary
Name	1-DEOXY-D-XYLULOSE-5-PHOSPHATE
Systematic Name (OpenEye OEToolkits)	[(2R,3S)-2,3-dihydroxy-4-oxo-pentyl] dihydrogen phosphate
Formula	C₅ H₁₁ O₇ P
Molecular Weight	214.11
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=P(O)(O)OCC(O)C(O)C(=O)C
SMILES	CACTVS	3.341	CC(=O)[CH](O)[CH](O)CO[P](O)(O)=O
SMILES	OpenEye OEToolkits	1.5.0	CC(=O)C(C(COP(=O)(O)O)O)O
Canonical SMILES	CACTVS	3.341	CC(=O)[C@@H](O)[C@H](O)CO[P](O)(O)=O
Canonical SMILES	OpenEye OEToolkits	1.5.0	CC(=O)[C@H]([C@@H](COP(=O)(O)O)O)O
InChI	InChI	1.03	InChI=1S/C5H11O7P/c1-3(6)5(8)4(7)2-12-13(9,10)11/h4-5,7-8H,2H2,1H3,(H2,9,10,11)/t4-,5-/m1/s1
InChIKey	InChI	1.03	AJPADPZSRRUGHI-RFZPGFLSSA-N

Drug Info: DrugBank

DrugBank ID	DB02496
Name	1-Deoxy-D-xylulose 5-phosphate
Groups	experimental
Description	1-Deoxy-D-xylulose 5-phosphate is a solid. This compound belongs to the pentose phosphates. These are carbohydrate derivatives containing a pentose substituted by one or more phosphate groups. The proteins that 1-Deoxy-D-xylulose 5-phosphate targets include 1-Deoxy-D-xylulose 5-phosphate reductoisomerase and pyridoxine 5'-phosphate synthase. 1-Deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway.
Synonyms	1-Deoxy-D-xylulose 5-phosphate
Categories	Carbohydrates Sugar Phosphates
CAS number	190079-18-6

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Pyridoxine 5'-phosphate synthase	MAELLLGVNIDHIATLRNARGTAYPDPVQAAFIAEQAGADGITVHLREDR...	unknown
1-deoxy-D-xylulose 5-phosphate reductoisomerase	MKQLTILGSTGSIGCSTLDVVRHNPEHFRVVALVAGKNVTRMVEQCLEFS...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682