FM2

2-(7-AMINO-6-METHYL-3H-PYRAZOLO[4,3-D]PYRIMIDIN-3-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL

Created:	2001-11-12
Last modified:	2020-06-05

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1 entries where FM2 is found as a standalone ligand

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Chemical Details
Formal Charge	1
Atom Count	36
Chiral Atom Count	4
Bond Count	38
Aromatic Bond Count	10

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Chemical Component Summary
Name	2-(7-AMINO-6-METHYL-3H-PYRAZOLO[4,3-D]PYRIMIDIN-3-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL
Synonyms	6-METHYL-FORMYCIN A
Systematic Name (OpenEye OEToolkits)	(2S,3R,4S,5R)-2-(7-amino-6-methyl-1H-pyrazolo[4,5-d]pyrimidin-6-ium-3-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Formula	C₁₁ H₁₆ N₅ O₄
Molecular Weight	282.276
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	OC1C(OC(CO)C1O)c3nnc2c(N)[n+](cnc23)C
SMILES	CACTVS	3.341	C[n+]1cnc2c([nH]nc2[CH]3O[CH](CO)[CH](O)[CH]3O)c1N
SMILES	OpenEye OEToolkits	1.5.0	C[n+]1cnc2c(c1N)[nH]nc2C3C(C(C(O3)CO)O)O
Canonical SMILES	CACTVS	3.341	C[n+]1cnc2c([nH]nc2[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c1N
Canonical SMILES	OpenEye OEToolkits	1.5.0	C[n+]1cnc2c(c1N)[nH]nc2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O
InChI	InChI	1.03	InChI=1S/C11H15N5O4/c1-16-3-13-5-6(14-15-7(5)11(16)12)10-9(19)8(18)4(2-17)20-10/h3-4,8-10,17-19H,2H2,1H3,(H2,12,14,15)/p+1/t4-,8-,9-,10+/m1/s1
InChIKey	InChI	1.03	UHYKIYIKTWEXSX-LFAOKBQASA-O

Drug Info: DrugBank

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

DrugBank ID	DB03986
Name	6-methyl-formycin A
Groups	experimental
Synonyms	2-(7-amino-6-methyl-3H-pyrazolo[4,3-d]pyrimidin-3-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol 6-methyl-formycin A

Drug Targets

DrugBank data are sourced from datasets licensed under a Creative Common's Attribution-NonCommercial 4.0 International License

Name	Target Sequence	Pharmacological Action	Actions
Purine nucleoside phosphorylase DeoD-type	MATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEDAREVNNVRGMLGFT...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682