FPM

(5R,6S)-6-(1-hydroxyethyl)-7-oxo-3-[(2R)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid

Created:	2007-11-27
Last modified:	2021-03-01

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2 entries where FPM is found as a standalone ligand

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Chemical Details
Formal Charge	0
Atom Count	34
Chiral Atom Count	4
Bond Count	36
Aromatic Bond Count	0

2D diagram of FPM

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Chemical Component Summary
Name	(5R,6S)-6-(1-hydroxyethyl)-7-oxo-3-[(2R)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
Synonyms	Faropenem
Systematic Name (OpenEye OEToolkits)	(5R,6S)-6-(1-hydroxyethyl)-7-oxo-3-[(2R)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
Formula	C₁₂ H₁₅ N O₅ S
Molecular Weight	285.316
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C2N1C(=C(SC1C2C(O)C)C3OCCC3)C(=O)O
SMILES	CACTVS	3.341	C[CH](O)[CH]1[CH]2SC(=C(N2C1=O)C(O)=O)[CH]3CCCO3
SMILES	OpenEye OEToolkits	1.5.0	CC(C1C2N(C1=O)C(=C(S2)C3CCCO3)C(=O)O)O
Canonical SMILES	CACTVS	3.341	C[C@@H](O)[C@@H]1[C@H]2SC(=C(N2C1=O)C(O)=O)[C@H]3CCCO3
Canonical SMILES	OpenEye OEToolkits	1.5.0	C[C@H]([C@@H]1[C@@H]2N(C1=O)C(=C(S2)[C@H]3CCCO3)C(=O)O)O
InChI	InChI	1.03	InChI=1S/C12H15NO5S/c1-5(14)7-10(15)13-8(12(16)17)9(19-11(7)13)6-3-2-4-18-6/h5-7,11,14H,2-4H2,1H3,(H,16,17)/t5-,6-,7+,11-/m1/s1
InChIKey	InChI	1.03	HGGAKXAHAYOLDJ-FHZUQPTBSA-N

Drug Info: DrugBank

DrugBank ID	DB12190
Name	Faropenem
Groups	investigational
Description	Faropenem has been used in trials studying the treatment of Tuberculosis, Pulmonary Tuberculosis, and Community Acquired Pneumonia.
Synonyms	Faropenem Faropenem Sodium
Categories	Amides Antibacterials for Systemic Use Antiinfectives for Systemic Use Heterocyclic Compounds, Fused-Ring Lactams Sulfur Compounds
ATC-Code	J01DI03
CAS number	106560-14-9

Related Resource References

Resource Name	Reference
PubChem	65894
ChEMBL	CHEMBL556262
ChEBI	CHEBI:51257

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.