G2F

2-deoxy-2-fluoro-alpha-D-glucopyranose

Created:	1999-07-08
Last modified:	2024-09-27

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6 entries where G2F is found as a standalone ligand15 entries where G2F is covalently linked to polymer or other heterogen groups 12 entries where G2F is found in a branched oligosaccharide

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Chemical Details
Formal Charge	0
Atom Count	23
Chiral Atom Count	5
Bond Count	23
Aromatic Bond Count	0

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Chemical Component Summary
Name	2-deoxy-2-fluoro-alpha-D-glucopyranose
Synonyms	2-deoxy-2-fluoro-alpha-D-glucose; 2-deoxy-2-fluoro-D-glucose; 2-deoxy-2-fluoro-glucose
Systematic Name (OpenEye OEToolkits)	(2S,3R,4S,5S,6R)-3-fluoro-6-(hydroxymethyl)oxane-2,4,5-triol
Formula	C₆ H₁₁ F O₅
Molecular Weight	182.147
Type	D-SACCHARIDE, ALPHA LINKING

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	12.01	FC1C(O)C(O)C(OC1O)CO
SMILES	CACTVS	3.370	OC[CH]1O[CH](O)[CH](F)[CH](O)[CH]1O
SMILES	OpenEye OEToolkits	1.7.0	C(C1C(C(C(C(O1)O)F)O)O)O
Canonical SMILES	CACTVS	3.370	OC[C@H]1O[C@H](O)[C@H](F)[C@@H](O)[C@@H]1O
Canonical SMILES	OpenEye OEToolkits	1.7.0	C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)F)O)O)O
InChI	InChI	1.03	InChI=1S/C6H11FO5/c7-3-5(10)4(9)2(1-8)12-6(3)11/h2-6,8-11H,1H2/t2-,3-,4-,5-,6+/m1/s1
InChIKey	InChI	1.03	ZCXUVYAZINUVJD-UKFBFLRUSA-N

Drug Info: DrugBank

DrugBank ID	DB04282
Name	2-deoxy-2-fluoro-α-D-glucose
Groups	experimental
Synonyms	2-DEOXY-2-FLUORO-GLUCOSE 2-deoxy-2-fluoro-α-D-glucose 2-deoxy-2-fluoro-alpha-D-glucose

Drug Targets

Name	Target Sequence	Pharmacological Action
Exoglucanase/xylanase	MPRTTPAPGHPARGARTALRTTRRRAATLVVGATVVLPAQAATTLKEAAD...	unknown
Beta-glucosidase A	MTIFQFPQDFMWGTATAAYQIEGAYQEDGRGLSIWDTFAHTPGKVFNGDN...	unknown
Cellulase B	MRTLRPQARAPRGLLAALGAVLAAFALVSSLVTAAAPAQADTTICEPFGT...	unknown
Lactase-phlorizin hydrolase	MELSWHVVFIALLSFSCWGSDWESDRNFISTAGPLTNDLLHNLSGLLGDQ...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682