HRG

L-HOMOARGININE

Created:	1999-12-16
Last modified:	2024-09-27

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7 entries where HRG is found as a standalone ligand15 entries where HRG is found in a polymer sequence

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Chemical Details
Formal Charge	0
Atom Count	29
Chiral Atom Count	1
Bond Count	28
Aromatic Bond Count	0

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Chemical Component Summary
Name	L-HOMOARGININE
Systematic Name (OpenEye OEToolkits)	(2S)-2-amino-6-carbamimidamido-hexanoic acid
Formula	C₇ H₁₆ N₄ O₂
Molecular Weight	188.228
Type	L-PEPTIDE LINKING

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C(O)C(N)CCCCNC(=[N@H])N
SMILES	CACTVS	3.341	N[CH](CCCCNC(N)=N)C(O)=O
SMILES	OpenEye OEToolkits	1.5.0	C(CCNC(=N)N)CC(C(=O)O)N
Canonical SMILES	CACTVS	3.341	N[C@@H](CCCCNC(N)=N)C(O)=O
Canonical SMILES	OpenEye OEToolkits	1.5.0	C(CCNC(=N)N)C[C@@H](C(=O)O)N
InChI	InChI	1.03	InChI=1S/C7H16N4O2/c8-5(6(12)13)3-1-2-4-11-7(9)10/h5H,1-4,8H2,(H,12,13)(H4,9,10,11)/t5-/m0/s1
InChIKey	InChI	1.03	QUOGESRFPZDMMT-YFKPBYRVSA-N

Drug Info: DrugBank

DrugBank ID	DB03974
Name	L-homoarginine
Groups	experimental
Synonyms	Homo-L-arginine L-homoarginine N6-amidino-Lysine N6-(Aminoiminomethyl)-L-lysine Homoarginine N6-amidino-L-Lysine
Categories	Amino Acids Amino Acids, Basic Amino Acids, Diamino Amino Acids, Peptides, and Proteins Arginine
CAS number	156-86-5

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Nitric oxide synthase, endothelial	MGNLKSVAQEPGPPCGLGLGLGLGLCGKQGPATPAPEPSRAPASLLPPAP...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682