LTN

L-TRYPTOPHANAMIDE

Created:	2002-08-08
Last modified:	2024-09-27

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3 entries where LTN is found as a standalone ligand1 entries where LTN is found in a polymer sequence

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Chemical Details
Formal Charge	0
Atom Count	28
Chiral Atom Count	1
Bond Count	29
Aromatic Bond Count	10

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Chemical Component Summary
Name	L-TRYPTOPHANAMIDE
Systematic Name (OpenEye OEToolkits)	(2S)-2-amino-3-(1H-indol-3-yl)propanamide
Formula	C₁₁ H₁₃ N₃ O
Molecular Weight	203.24
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=C(N)C(N)Cc2c1ccccc1nc2
SMILES	CACTVS	3.341	N[CH](Cc1c[nH]c2ccccc12)C(N)=O
SMILES	OpenEye OEToolkits	1.5.0	c1ccc2c(c1)c(c[nH]2)CC(C(=O)N)N
Canonical SMILES	CACTVS	3.341	N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Canonical SMILES	OpenEye OEToolkits	1.5.0	c1ccc2c(c1)c(c[nH]2)C[C@@H](C(=O)N)N
InChI	InChI	1.03	InChI=1S/C11H13N3O/c12-9(11(13)15)5-7-6-14-10-4-2-1-3-8(7)10/h1-4,6,9,14H,5,12H2,(H2,13,15)/t9-/m0/s1
InChIKey	InChI	1.03	JLSKPBDKNIXMBS-VIFPVBQESA-N

Drug Info: DrugBank

DrugBank ID	DB04537
Name	Tryptophanamide
Groups	experimental
Synonyms	(S)-alpha-Amino-1H-indole-3-propionamide Tryptophanamide L-tryptophanamide L-tryptophan amide
Categories	Amino Acids Amino Acids, Aromatic Amino Acids, Cyclic Amino Acids, Peptides, and Proteins
CAS number	20696-57-5

Drug Targets

Name	Target Sequence	Pharmacological Action	Actions
Tryptophan--tRNA ligase, cytoplasmic	MPNSEPASLLELFNSIATQGELVRSLKAGNASKDEIDSAVKMLVSLKMSY...	unknown
Tryptophan--tRNA ligase	MKTIFSGIQPSGVITIGNYIGALRQFVELQHEYNCYFCIVDQHAITVWQD...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682