R52

5-O-phosphono-D-ribose

Created:	2008-06-10
Last modified:	2011-06-04

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2 entries where R52 is found as a standalone ligand

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Chemical Details
Formal Charge	0
Atom Count	25
Chiral Atom Count	3
Bond Count	24
Aromatic Bond Count	0

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Chemical Component Summary
Name	5-O-phosphono-D-ribose
Systematic Name (OpenEye OEToolkits)	[(2R,3R,4R)-2,3,4-trihydroxy-5-oxo-pentyl] dihydrogen phosphate
Formula	C₅ H₁₁ O₈ P
Molecular Weight	230.11
Type	NON-POLYMER

Chemical Descriptors
Type	Program	Version	Descriptor
SMILES	ACDLabs	10.04	O=P(O)(O)OCC(O)C(O)C(O)C=O
SMILES	CACTVS	3.341	O[CH](CO[P](O)(O)=O)[CH](O)[CH](O)C=O
SMILES	OpenEye OEToolkits	1.5.0	C(C(C(C(C=O)O)O)O)OP(=O)(O)O
Canonical SMILES	CACTVS	3.341	O[C@H](CO[P](O)(O)=O)[C@@H](O)[C@@H](O)C=O
Canonical SMILES	OpenEye OEToolkits	1.5.0	C([C@H]([C@H]([C@H](C=O)O)O)O)OP(=O)(O)O
InChI	InChI	1.03	InChI=1S/C5H11O8P/c6-1-3(7)5(9)4(8)2-13-14(10,11)12/h1,3-5,7-9H,2H2,(H2,10,11,12)/t3-,4+,5-/m0/s1
InChIKey	InChI	1.03	PPQRONHOSHZGFQ-LMVFSUKVSA-N

Drug Info: DrugBank

DrugBank ID	DB02053
Name	Ribose-5-phosphate
Groups	experimental
Synonyms	5-O-phosphono-D-ribose Ribose-5-phosphate aldehydo-D-ribose 5-phosphate D-Ribose 5-phosphate
Categories	Carbohydrates Pentosephosphates Sugar Phosphates
CAS number	4151-19-3

Drug Targets

Name	Target Sequence	Pharmacological Action
Ribose-5-phosphate isomerase A	MERPLESYKKEAAHAAIAYVQDGMVVGLGTGSTARYAVLELARRLREGEL...	unknown
2-dehydro-3-deoxyphosphooctonate aldolase	MEKFLVIAGPCAIESEELLLKVGEEIKRLSEKFKEVEFVFKSSFDKANRS...	unknown
ADP-ribose pyrophosphatase	MGRVYYGGVERTYLYRGRILNLALEGRYEIVEHKPAVAVIALREGRMLFV...	unknown

Drug Info/Drug Targets: DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS. Nucleic Acids Res. 2011 Jan; 39 (Database issue):D1035-41. | PMID:21059682